Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Elvis Cuevas"'
Autor:
Zahra Kolahchi, Nicholas Henkel, Mahmoud A. Eladawi, Emma C. Villarreal, Prathik Kandimalla, Anna Lundh, Robert E. McCullumsmith, Elvis Cuevas
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8485 (2024)
Two-thirds of Americans with Alzheimer’s disease are women, indicating a profound variance between the sexes. Variances exist between the sexes in the age and intensity of the presentation, cognitive deficits, neuroinflammatory factors, structural
Externí odkaz:
https://doaj.org/article/6d9ce41528ad4425807c39755f7262c0
Publikováno v:
Toxicology Reports, Vol 9, Iss , Pp 806-813 (2022)
The pathophysiology underlying the loss of dopaminergic neurons in Parkinson’s disease (PD) is unclear. A gap of knowledge in the molecular and cellular events leading to degeneration of the nigrostriatal DA system is a major barrier to the develop
Externí odkaz:
https://doaj.org/article/659cd74f08e64897b54d3a68fe7918d1
Autor:
Paola Flores-Rodríguez, B. Berenice Campa-Córdoba, Marely Bravo-Muñoz, Miguel Ángel Ontiveros-Torres, Mar Pacheco-Herrero, Luis O Soto-Rojas, Linda Garcés-Ramírez, Ricardo Apátiga-Pérez, Nabil Itzi Luna-Viramontes, José Francisco Montiel-Sosa, Ignacio Villanueva-Fierro, José Luna-Muñoz, Elvis Cuevas, Fidel de la Cruz
Publikováno v:
Metabolic Brain Disease. 37:39-50
Alzheimer's disease (AD) is clinically characterized by a progressive loss of cognitive functions and short-term memory. AD patients present two distinctive neuropathological lesions: neuritic plaques and neurofibrillary tangles (NFTs), constituted o
Publikováno v:
Brain, Behavior, and Immunity
Highlights • SARS-CoV-2 may infect immature olfactory sense neurons. • Olfactory sense neurons and the blood brain barrier may allow infection of the brain. • The distribution of ACE2, or novel cellular entry proteins, will limit viral spread.
Tauroursodeoxycholic acid (TUDCA) is neuroprotective in a chronic mouse model of Parkinson’s disease
Autor:
Sumit Sarkar, Aida G Guzman Lopez, Srinivasulu Chigurupati, Susan M. Burks, Nancy P. Gomez-Crisostomo, Bonnie L. Robinson, Claudia Escudero-Lourdes, Joseph P. Hanig, James Raymick, Sherry A. Ferguson, Elvis Cuevas
Publikováno v:
Nutritional Neuroscience. 25:1374-1391
Parkinson's disease (PD) is a progressive motor disease of unknown etiology. Although neuroprotective ability of endogenous bile acid, tauroursodeoxycholic acid (TUDCA), shown in various diseases, including an acute model of PD,the potential therapeu
Publikováno v:
Neuroscience. 440:48-55
Alzheimer's disease (AD) pathology is characterized by amyloid plaques containing amyloid beta (Aβ) peptides, neurofibrillary tangles containing hyperphosphorylated tau protein, and neuronal loss. In addition, Aβ deposition in brain microvessels, k
Autor:
Iris N Serratos, Pilar Castellanos, Nina Pastor, César Millán-Pacheco, Daniel Rembao, Ruy Pérez-Montfort, Nallely Cabrera, Francisco Reyes-Espinosa, Paulina Díaz-Garrido, Ambar López-Macay, Karina Martínez-Flores, Alberto López-Reyes, Aurora Sánchez-García, Elvis Cuevas, Abel Santamaria
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120221 (2015)
The receptor for advanced glycation end products (RAGE) is a pattern-recognition receptor involved in neurodegenerative and inflammatory disorders. RAGE induces cellular signaling upon binding to a variety of ligands. Evidence suggests that RAGE up-r
Externí odkaz:
https://doaj.org/article/c2c05799de3241249d12296d41def1f5
Publikováno v:
Molecular Neurobiology. 57:32-40
One of the most abundant proteins expressed in the brain, 14-3-3 comprises about 1% of the brain's total soluble proteins. The 14-3-3 isoforms bind to specific phosphoserine- and phosphothreonine-containing motifs found on a variety of signaling prot
Autor:
Elvis Cuevas, Susan M. Burks, Sumit Sarkar, Syed F. Ali, Hector Rosas-Hernandez, Aida Guzman, Syed Z. Imam, Manuel A. Ramirez-Lee
Publikováno v:
Metabolic Brain Disease. 34:1365-1374
The amyloid β-peptide (Aβ) is transported across the blood-brain barrier (BBB) by binding with the receptor for advanced glycation end products (RAGE). Previously, we demonstrated that the Aβ fraction 25–35 (Aβ25–35) increases RAGE expression
Autor:
Merle G. Paule, Syed Z. Imam, Waqar Majeed, Claudia Escudero-Lourdes, Shawn E. Bourdo, Syed F. Ali, Hector Rosas-Hernandez, Susan M. Lantz, Elvis Cuevas, Alexandru S. Biris, Manuel A. Ramirez-Lee
Publikováno v:
Journal of Applied Toxicology. 39:966-973
Graphene-based nanomaterials hold the potential to be used in a wide variety of applications, including biomedical devices. Pristine graphene (PG) is an un-functionalized, defect-free type of graphene that could be used as a material for neural inter