Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Elvira T. Derbyshire"'
Autor:
Ksenija Slavic, Amanda Tattersall, Sanjeev Krishna, Henry M. Staines, Elvira T. Derbyshire, Henri Vial
Publikováno v:
Trends in Parasitology. 26:284-296
Mammalian transport proteins are essential components of cellular function that have been very successfully exploited as drug targets. Over the past few years, a small but increasing number of Plasmodium transport proteins have been validated as bein
Publikováno v:
Molecular and Biochemical Parasitology
Here we have investigated the inhibitory properties of green tea catechins on the Plasmodium falciparum hexose transporter (PfHT), the Babesia bovis hexose transporter 1 (BboHT1) and the mammalian facilitative glucose transporters, GLUT1 and GLUT5, e
Autor:
Henry M. Staines, Elvira T. Derbyshire, Catarina A. Marques, Maria M. Mota, Miguel Prudêncio, Sanjeev Krishna
Publikováno v:
Cellular Microbiology
Parasite infection can lead to alterations in the permeability of host plasma membranes. Presented here is the first demonstration that this phenomenon occurs in Plasmodium-infected liver cells. Using the whole-cell patch-clamp technique, volume-regu
Autor:
Elvira T. Derbyshire, Charles J. Woodrow, Christophe Morin, Erik de Vries, Sanjeev Krishna, Henry M. Staines, Frits Franssen
Publikováno v:
Molecular and Biochemical Parasitology
Babesia are tick-transmitted haemoprotozoan parasites that infect cattle, with an estimated 500 million at risk worldwide. Here, two predicted hexose transporters (BboHT1 and 2) have been identified within the Babesia bovis genome. BboHT1, having 40%
Autor:
Patrick Verloo, Ajay Pillai, Henry M. Staines, Abdulnaser Alkhalil, Sanjay A. Desai, Florian Lang, Richard J.W. Allen, Serge Thomas, Sherin J. Rouhani, Kempaiah Rayavara, Kevin J. Saliba, Eugene K. Oteng, Hugo R. de Jonge, Elvira T. Derbyshire, Kiaran Kirk, Godfrey Lisk, Stéphane Egée, Tsione Solomon, Stephan M. Huber, Hagai Ginsburg, David R.C. Hill, Crystal Shen
Publikováno v:
International Journal for Parasitology
International Journal for Parasitology, Elsevier, 2007, 37 (5), pp.475-82. ⟨10.1016/j.ijpara.2006.12.013⟩
International Journal for Parasitology, 2007, 37 (5), pp.475-82. ⟨10.1016/j.ijpara.2006.12.013⟩
International Journal for Parasitology, 37(5), 475-482. Elsevier Ltd.
International Journal for Parasitology, Elsevier, 2007, 37 (5), pp.475-82. ⟨10.1016/j.ijpara.2006.12.013⟩
International Journal for Parasitology, 2007, 37 (5), pp.475-82. ⟨10.1016/j.ijpara.2006.12.013⟩
International Journal for Parasitology, 37(5), 475-482. Elsevier Ltd.
International audience; The altered permeability characteristics of erythrocytes infected with malaria parasites have been a source of interest for over 30 years. Recent electrophysiological studies have provided strong evidence that these changes re
Autor:
Robert E. Sinden, Elvira T. Derbyshire, Christophe Morin, Henry M. Staines, Michael J. Delves, Ursula Straschil, Rita Tewari, Maria M. Mota, Zhengyao Xu, Arthur M. Talman, Ksenija Slavic, Sanjeev Krishna, Miguel Prudêncio
Publikováno v:
Antimicrobial Agents and Chemotherapy; Vol 55
During blood infection, malarial parasites use d -glucose as their main energy source. The Plasmodium falciparum hexose transporter (PfHT), which mediates the uptake of d -glucose into parasites, is essential for survival of asexual blood-stage paras
Publikováno v:
Malaria Journal; Vol 10
Malaria Journal
Malaria Journal, Vol 10, Iss 1, p 165 (2011)
Malaria Journal
Malaria Journal, Vol 10, Iss 1, p 165 (2011)
Glucose is the primary source of energy and a key substrate for most cells. Inhibition of cellular glucose uptake (the first step in its utilization) has, therefore, received attention as a potential therapeutic strategy to treat various unrelated di