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pro vyhledávání: '"Elvira Peit"'
Autor:
Elvira Peit, Kodandaramireddy Nalapareddy, Michael R. Speicher, Eva M. Hoffmann, Hans A. Kestler, Anna C. Obenauf, Esther Danenberg, K. Lenhard Rudolph, Yvonne Begus-Nahrmann, Nick Barker, André Lechel, Peter Schirmacher, Falk Schlaudraff, Birgit Liss, Hans Clevers
Publikováno v:
Nature Genetics, 41(10), 1138-1143. Nature Publishing Group
Telomere dysfunction limits the proliferative capacity of human cells and induces organismal aging by activation of p53 and p21. Although deletion of p21 elongates the lifespan of telomere-dysfunctional mice, a direct analysis of p53 in telomere-rela