Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Elvira P. Leites"'
Autor:
Elvira P. Leites, Vanessa A. Morais
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102869- (2024)
Externí odkaz:
https://doaj.org/article/20800f701c3c46eeb20a3e8f813f937a
Autor:
João Conde, Ruth A. Pumroy, Charlotte Baker, Tiago Rodrigues, Ana Guerreiro, Bárbara B. Sousa, Marta C. Marques, Bernardo P. de Almeida, Sohyon Lee, Elvira P. Leites, Daniel Picard, Amrita Samanta, Sandra H. Vaz, Florian Sieglitz, Maike Langini, Marc Remke, Rafael Roque, Tobias Weiss, Michael Weller, Yuhang Liu, Seungil Han, Francisco Corzana, Vanessa A. Morais, Cláudia C. Faria, Tânia Carvalho, Panagis Filippakopoulos, Berend Snijder, Nuno L. Barbosa-Morais, Vera Y. Moiseenkova-Bell, Gonçalo J. L. Bernardes
Publikováno v:
ACS Central Science, Vol 7, Iss 5, Pp 868-881 (2021)
Externí odkaz:
https://doaj.org/article/13e41edb1f1f40069a060c39b209935b
Publikováno v:
Cells, Vol 10, Iss 1395, p 1395 (2021)
Cells
Cells
Mitochondrial dysfunction has a fundamental role in the development of idiopathic and familiar forms of Parkinson’s disease (PD). The nuclear-encoded mitochondrial kinase PINK1, linked to familial PD, is responsible for diverse mechanisms of mitoch
Autor:
Berend Snijder, Francisco Corzana, Charlotte Baker, Claudia C. Faria, Amrita Samanta, Panagis Filippakopoulos, Nuno L. Barbosa-Morais, Marta C. Marques, João Conde, Daniel Picard, Marc Remke, Gonçalo J. L. Bernardes, Yuhang Liu, Tânia Carvalho, Ruth A. Pumroy, Florian Sieglitz, Sohyon Lee, Vera Y. Moiseenkova-Bell, Sandra H. Vaz, Bárbara B. Sousa, Rafael Roque, Bernardo P. de Almeida, Elvira P. Leites, Michael Weller, Seungil Han, Vanessa Alexandra Morais, Tobias Weiss, Tiago Rodrigues, Ana Guerreiro, Maike Langini
Publikováno v:
ACS Central Science
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
ACS Central Science, Vol 7, Iss 5, Pp 868-881 (2021)
ACS Central Science, 7 (5)
ACS central science
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
ACS Central Science, Vol 7, Iss 5, Pp 868-881 (2021)
ACS Central Science, 7 (5)
ACS central science
The use of computational tools to identify biological targets of natural products with anticancer properties and unknown modes of action is gaining momentum. We employed self-organizing maps to deconvolute the phenotypic effects of piperlongumine (PL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d11cc7bf34a63d2c20e06950f58cbf6
https://www.repository.cam.ac.uk/handle/1810/324869
https://www.repository.cam.ac.uk/handle/1810/324869
Publikováno v:
Biochemical and Biophysical Research Communications
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
© 2017 Published by Elsevier Inc.
Mitochondria have a pivotal role in the maintenance of cell homeostasis and survival. Mitochondria are involved in processes such as ATP production, reactive oxygen species production, apoptosis induction, calc
Mitochondria have a pivotal role in the maintenance of cell homeostasis and survival. Mitochondria are involved in processes such as ATP production, reactive oxygen species production, apoptosis induction, calc
Autor:
Ann Geens, Bart De Strooper, Patrik Verstreken, Thora Lohnau, Matteo Rossi, Christine Klein, Elvira P. Leites, Sarah-Maria Fendt, Melissa Vos, Claudia Böhm, Liesbeth Deaulmerie, Philip Seibler, Vanessa A. Morais, Aleksandar Rakovic, Katleen Craessaerts, Jef Swerts
Publikováno v:
The Journal of Cell Biology
Parkinson’s disease–causing mutations in PINK1 yield mitochondrial defects including inefficient electron transport between complex I and ubiquinone. Vos et al. show that genetic and pharmacological inhibition of fatty acid synthase bypass these
Publikováno v:
Cells, Vol 10, Iss 6, p 1395 (2021)
Mitochondrial dysfunction has a fundamental role in the development of idiopathic and familiar forms of Parkinson’s disease (PD). The nuclear-encoded mitochondrial kinase PINK1, linked to familial PD, is responsible for diverse mechanisms of mitoch
Externí odkaz:
https://doaj.org/article/701794bceb5f4a88985dacaae5416ba2