Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Elvira M.G. van Bommel"'
Publikováno v:
Pharmaceutical Research. 15:557-561
Purpose. The purpose of this study was to investigate the effect of the formulation parameters on the characteristics of dextran-based microspheres, prepared in an all-aqueous system.
Publikováno v:
International Journal of Pharmaceutics. 72:19-27
A mathematical model is presented with which acetaminophen release curves from the gradient matrix system (GMS) with different geometries (slabs and spheres) can be described. Diffusion is considered the rate-controlling step in the release process.
Publikováno v:
International journal of pharmaceutics. 183(1)
A novel procedure to prepare dextran microspheres, without the use of organic solvents was developed. The method is based on phase separation which occurs in aqueous solutions of PEG and methacrylated dextran (dexMA). After stirring this two phase sy