Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Elvira Immacolata Parrotta"'
Autor:
Stefania Scalise, Clara Zannino, Valeria Lucchino, Michela Lo Conte, Vittorio Abbonante, Giorgia Lucia Benedetto, Mariangela Scalise, Antonio Gambardella, Elvira Immacolata Parrotta, Giovanni Cuda
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Prolonged febrile seizures (FS) in children are linked to the development of temporal lobe epilepsy (MTLE). The association between these two pathologies may be ascribed to the long-term effects that FS exert on neural stem cells, negatively
Externí odkaz:
https://doaj.org/article/312ac296e2f2429caa9049a45606b587
Autor:
Costanza Maria Cristiani, Luana Scaramuzzino, Andrea Quattrone, Elvira Immacolata Parrotta, Giovanni Cuda, Aldo Quattrone
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 6882 (2024)
Clinical differentiation of progressive supranuclear palsy (PSP) from Parkinson’s disease (PD) is challenging due to overlapping phenotypes and the late onset of specific atypical signs. Therefore, easily assessable diagnostic biomarkers are highly
Externí odkaz:
https://doaj.org/article/de56818cba5b4dbc9c04b10db5671cd2
Autor:
Mariangela Scalise, Fabiola Marino, Luca Salerno, Teresa Mancuso, Donato Cappetta, Antonella Barone, Elvira Immacolata Parrotta, Annalaura Torella, Domenico Palumbo, Pierangelo Veltri, Antonella De Angelis, Liberato Berrino, Francesco Rossi, Alessandro Weisz, Marcello Rota, Konrad Urbanek, Bernardo Nadal-Ginard, Daniele Torella, Eleonora Cianflone
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Scalise et al. examine the mRNAome and miRNAome of cardiomyocytes differentiated from murine adult cardiac stem cells (CSCs). Their results show that the differentiation process follows a trajectory of miRNA/mRNA expression that resembles that of adu
Externí odkaz:
https://doaj.org/article/3cd4564e0a304741913001dfdd3c1641
Autor:
Valeria Lucchino, Luana Scaramuzzino, Stefania Scalise, Michela Lo Conte, Clara Zannino, Giorgia Lucia Benedetto, Umberto Aguglia, Edoardo Ferlazzo, Giovanni Cuda, Elvira Immacolata Parrotta
Publikováno v:
Cells, Vol 11, Iss 21, p 3491 (2022)
Unverricht-Lundborg disease (ULD), also known as progressive myoclonic epilepsy 1 (EPM1), is a rare autosomal recessive neurodegenerative disorder characterized by a complex symptomatology that includes action- and stimulus-sensitive myoclonus and to
Externí odkaz:
https://doaj.org/article/6d6a8c7fef864716addbdb6e971790c6
Autor:
Valeria Lucchino, Luana Scaramuzzino, Stefania Scalise, Katia Grillone, Michela Lo Conte, Claudia Esposito, Umberto Aguglia, Edoardo Ferlazzo, Nicola Perrotti, Paola Malatesta, Elvira Immacolata Parrotta, Giovanni Cuda
Publikováno v:
Stem Cell Research, Vol 53, Iss , Pp 102329- (2021)
Unverricht-Lundborg disease (ULD) is an inherited form of progressive myoclonus epilepsy caused by mutations in the gene encoding Cystatin B (CSTB), an inhibitor of lysosomal proteases. The most common mutation described in ULD patients is an unstabl
Externí odkaz:
https://doaj.org/article/2cda4cafb2f6426f83e831cd6607d212
Autor:
Stefania Scalise, Clara Zannino, Valeria Lucchino, Michela Lo Conte, Luana Scaramuzzino, Pierangelo Cifelli, Tiziano D’Andrea, Katiuscia Martinello, Sergio Fucile, Eleonora Palma, Antonio Gambardella, Gabriele Ruffolo, Giovanni Cuda, Elvira Immacolata Parrotta
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1075 (2022)
Mutations in SCN1A gene, encoding the voltage-gated sodium channel (VGSC) NaV1.1, are widely recognized as a leading cause of genetic febrile seizures (FS), due to the decrease in the Na+ current density, mainly affecting the inhibitory neuronal tran
Externí odkaz:
https://doaj.org/article/4bda5b3dc42a4f45a71703891618758f
Autor:
Stefania Scalise, Luana Scaramuzzino, Valeria Lucchino, Claudia Esposito, Paola Malatesta, Katia Grillone, Nicola Perrotti, Giovanni Cuda, Elvira Immacolata Parrotta
Publikováno v:
Stem Cell Research, Vol 49, Iss , Pp 102083- (2020)
Here, we described the generation of human induced pluripotent stem cell lines (hiPSCs) from fibroblasts isolated by punch biopsies of two siblings carrying inherited mutation (c.434 T > C) in the SCN1A gene, encoding for the neuronal voltage gated s
Externí odkaz:
https://doaj.org/article/1e27504d898d498da44ee1e5ea86caf7
Autor:
Luana Scaramuzzino, Valeria Lucchino, Stefania Scalise, Michela Lo Conte, Clara Zannino, Alessandro Sacco, Flavia Biamonte, Elvira Immacolata Parrotta, Francesco Saverio Costanzo, Giovanni Cuda
Publikováno v:
Cells, Vol 10, Iss 9, p 2431 (2021)
Embryonic stem cells (ESCs) are pluripotent cells with indefinite self-renewal ability and differentiation properties. To function properly and maintain genomic stability, ESCs need to be endowed with an efficient repair system as well as effective r
Externí odkaz:
https://doaj.org/article/64953880bb5046bfb1d5536397ff0e23
Autor:
Elvira Immacolata Parrotta, Anna Procopio, Stefania Scalise, Claudia Esposito, Giovanni Nicoletta, Gianluca Santamaria, Maria Teresa De Angelis, Tatjana Dorn, Alessandra Moretti, Karl-Ludwig Laugwitz, Francesco Montefusco, Carlo Cosentino, Giovanni Cuda
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 2004 (2021)
Arrhythmogenic Right Ventricular cardiomyopathy (ARVC) is an inherited cardiac muscle disease linked to genetic deficiency in components of the desmosomes. The disease is characterized by progressive fibro-fatty replacement of the right ventricle, wh
Externí odkaz:
https://doaj.org/article/52db38db11b846f6ab8ce57bd37bec86
Autor:
Eleonora Cianflone, Donato Cappetta, Teresa Mancuso, Jolanda Sabatino, Fabiola Marino, Mariangela Scalise, Michele Albanese, Alessandro Salatino, Elvira Immacolata Parrotta, Giovanni Cuda, Antonella De Angelis, Liberato Berrino, Francesco Rossi, Bernardo Nadal-Ginard, Daniele Torella, Konrad Urbanek
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 7927 (2020)
The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) exert pleiotropic effects on cardiac cell biology which are not yet fully understood. Here we tested whether statin treatment affects resident endogenous cardiac stem/
Externí odkaz:
https://doaj.org/article/f521dd1c01c64166b61811ec4382512b