Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Elvira Haas"'
Autor:
Edouard Battegay, Elvira Haas, Katja Drägert, Indranil Bhattacharya, Michael N. Hall, Rok Humar
Publikováno v:
Biochemical and Biophysical Research Communications. 473:317-322
In adipose tissue mTOR complex 2 (mTORC2) contributes to the regulation of glucose/lipid metabolism and inflammatory molecule expression. Both processes display diurnal variations during the course of the day. RICTOR and mSIN1 are unique and essentia
Autor:
Katja Drägert, Edouard Battegay, Elvira Haas, Rok Humar, Ana Pérez Dominguez, Indranil Bhattacharya
Publikováno v:
Biochemical and Biophysical Research Communications. 461:287-292
Obesity involves hypoxic adipose tissue and low-grade chronic inflammation. We investigated the impact of hypoxia on inflammatory response to TNF-α in white and brown adipocytes. In response to TNF-α, the expression of the inducible enzymes iNOS an
Autor:
Matthias Barton, Martin Kretz, Corinne C Widmer, Indranil Bhattacharya, Alexa L. Mundy, Elvira Haas, Roberta Minotti, Regina Hofmann-Lehmann
Objective: Angiotensin II (Ang II), endothelin-1 (ET-1) and reactive oxygen species (ROS) have been implicated in the development of pathologic changes associated with obesity including hypertension and atherosclerosis. The aim of this study was to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed99dd6b603cc762158fec19c05b89bc
http://doc.rero.ch/record/290633/files/73-2-368.pdf
http://doc.rero.ch/record/290633/files/73-2-368.pdf
Autor:
Lukas Zimmerli, Marlen Damjanović, Michael N. Hall, Verena Albert, Emmanuel Contassot, Asami Hagiwara, Katja Drägert, Indranil Bhattacharya, Rok Humar, Elvira Haas, Edouard Battegay
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 33:2105-2111
Objective— Perivascular adipose tissue (PVAT) wraps blood vessels and modulates vasoreactivity by secretion of vasoactive molecules. Mammalian target of rapamycin complex 2 (mTORC2) has been shown to control inflammation and is expressed in adipose
Autor:
Elvira Haas, Edouard Battegay, Jürg Schwaller, Rok Humar, Thomas Walpen, Martin Peier, Ina Kalus
Publikováno v:
Cellular physiology and biochemistry : international journal of experimental cellular physiology bi
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
Background: PIM1 is a constitutively active serine-threonine kinase regulating cell survival and proliferation. Increased PIM1 expression has been correlated with cancer metastasis by facilitating migration and anti-adhesion. Endothelial cells play a
Autor:
Edouard Battegay, Fabio Aimi, Perparim Limani, Ina Kalus, Fabienne Lehner, Michael N. Hall, Markus A. Rüegg, Vinicius Gomes de Lima, Stavroula Georgiopoulou, Rok Humar, Nicole Lindenblatt, Elvira Haas, Alica Hegglin
Publikováno v:
Scientific Reports
To explore the general requirement of endothelial mTORC2 during embryonic and adolescent development, we knocked out the essential mTORC2 component Rictor in the mouse endothelium in the embryo, during adolescence and in endothelial cells in vitro. D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf930757687aec52d03aec28b07c6a1
https://edoc.unibas.ch/40079/
https://edoc.unibas.ch/40079/
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 27:1669-1672
Despite the clear-cut epidemiological evidence of protective effects of endogenous estrogens in premenopausal women,1,2 the results of randomized clinical trials using conjugated equine estrogens and medroxyprogesterone acetate instead of natural hor
Autor:
Roberta Minotti, Elvira Haas, Christoph Stettler, Indranil Bhattacharya, Huige Li, Matthias Barton, Tobias Traupe
Publikováno v:
Hypertension. 49:1364-1370
This study investigated the contribution of estrogen receptors (ERs) α and β for epicardial coronary artery function, vascular NO bioactivity, and superoxide (O 2 − ) formation. Porcine coronary rings were suspended in organ chambers and precontr
Autor:
Ulrike Held, Margarete Arras, Rok Humar, Elvira Haas, Przemyslaw Blyszczuk, Stavroula Georgiopoulou, Edouard Battegay, Indranil Bhattacharya, Petra Seebeck, Michael N. Hall, Katja Drägert, Giovanni Pellegrini, Steven A. Brown, Abdelhalim Azzi
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 66(2)
The mammalian target of rapamycin complex 2 (mTORC2) contains the essential protein RICTOR and is activated by growth factors. mTORC2 in adipose tissue contributes to the regulation of glucose and lipid metabolism. In the perivascular adipose tissue,
Autor:
Karin Moelling, Gabriela Burkard, Elvira Haas, Marc Schweneker, André S. Bachmann, Sven Zimmermann, Thorsten Fritzius, Jochen Heinrich, Magnus Bosse, Antje Caelers, Alexander D. Frey
Publikováno v:
Biochemical Journal. 399:9-20
WD (tryptophan-aspartic acid dipeptide)-repeat proteins play a central role in signal transduction cascades by co-ordinating the interaction of key signalling molecules. We identified a novel propeller-FYVE [domain identified in Fab1p, YOTB, Vac1p an