Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Elvira Alfaro-Arnedo"'
Autor:
Patricia Pérez-Matute, Icíar P. López, María Íñiguez, Emma Recio-Fernández, Raquel Torrens, Sergio Piñeiro-Hermida, Elvira Alfaro-Arnedo, Luong Chau, Christina Walz, Andreas Hoeflich, José A. Oteo, José G. Pichel
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
ObjectiveWe aimed to investigate the short and long-term metabolic consequences of IGF1R systemic gene deficiency in mice.MethodsUBC-CreERT2, Igf1rfl/fl mutant mice were used to suppress IGF1R signaling in adult tissues by inducing postnatal generali
Externí odkaz:
https://doaj.org/article/d487c97cd50643339ffa6225129c7e2c
Autor:
Elvira Alfaro-Arnedo, Icíar P. López, Sergio Piñeiro-Hermida, Álvaro C. Ucero, Francisco J. González-Barcala, Francisco J. Salgado, José G. Pichel
Publikováno v:
Biomedicines, Vol 10, Iss 4, p 733 (2022)
In the original article [...]
Externí odkaz:
https://doaj.org/article/69a94a3ae23a4e8cb2a0229ed47bc2b4
Autor:
Elvira Alfaro-Arnedo, Icíar P. López, Sergio Piñeiro-Hermida, Álvaro C. Ucero, Francisco J. González-Barcala, Francisco J. Salgado, José G. Pichel
Publikováno v:
Biomedicines, Vol 9, Iss 8, p 912 (2021)
Background: Asthma is a chronic lung disease characterized by reversible airflow obstruction, airway hyperresponsiveness (AHR), mucus overproduction and inflammation. Although Insulin-like growth factor 1 receptor (IGF1R) was found to be involved in
Externí odkaz:
https://doaj.org/article/6f9f70010fbb421d90ef8f772e6d3392
Autor:
Sergio Piñeiro-Hermida, Icíar P. López, Elvira Alfaro-Arnedo, Raquel Torrens, María Iñiguez, Lydia Alvarez-Erviti, Carlos Ruíz-Martínez, José G. Pichel
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract IGF1R (Insulin-like Growth Factor 1 Receptor) is a tyrosine kinase with pleiotropic cellular functions. IGF activity maintains human lung homeostasis and is implicated in pulmonary diseases such as cancer, ARDS, COPD, asthma and fibrosis. He
Externí odkaz:
https://doaj.org/article/3b2793cee94e4995ba43123296da8895
Autor:
Sergio Piñeiro-Hermida, Elvira Alfaro-Arnedo, Joshua A Gregory, Raquel Torrens, Carlos Ruíz-Martínez, Mikael Adner, Icíar P López, José G Pichel
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0190159 (2017)
Asthma is a chronic inflammatory disease characterized by bronchial hyperresponsiveness, mucus overproduction and airway remodeling. Notably, we have recently demonstrated that insulin-like growth factor 1 receptor (IGF1R) deficiency in mice attenuat
Externí odkaz:
https://doaj.org/article/af15676d209e4d1a9ee47fddd1eea8b3
Autor:
Elvira Alfaro-Arnedo, Icíar P. López, Sergio Piñeiro-Hermida, Marta Canalejo, Carolina Gotera, Jesús Javier Sola, Alejandra Roncero, Germán Peces-Barba, Carlos Ruíz-Martínez, José G. Pichel
Publikováno v:
Oncogene. 41:3625-3639
Given the long-term ineffectiveness of current therapies and late-stage diagnoses, lung cancer is a leading cause of malignant diseases. Tumor progression is influenced by cancer cell interactions with the tumor microenvironment (TME). Insulin-like g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5411a0a79b7c9b83837e44f23f45af97
https://doi.org/10.1038/s41388-022-02376-w
https://doi.org/10.1038/s41388-022-02376-w
Autor:
Laura Fernández-Blanco, Maria J. Calzada, Sandra Pérez-Rial, David Labrousse-Arias, Javier Sevilla-Montero, Icíar P. López, José G. Pichel, Gema Mondejar-Parreño, Germán Peces-Barba, Angel Cogolludo, Bianca Barreira, Elvira Alfaro-Arnedo, Victor I. Peinado, Cintia Fernández-Pérez
Publikováno v:
American Journal of Respiratory and Critical Care Medicine
Rationale: Cigarette smoke is considered the chief leading cause of chronic obstructive pulmonary disease (COPD). Its impact on the progressive deterioration of airways has been extensively studied...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::654600b15a4e4a6a21ed59b72f9b00c7
https://doi.org/10.1164/rccm.201911-2238oc
https://doi.org/10.1164/rccm.201911-2238oc
Autor:
José Manuel García Pichel, Icíar P. López, Sergio Piñeiro-Hermida, Marta Canalejo, Carolina Gotera, Jesús J. Sola, Alejandra Roncero, Germán Peces-Barba, Carlos Ruíz-Martínez, Elvira Alfaro-Arnedo
Publikováno v:
Molecular pathology and functional genomics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5a07c35ec846e24a92c59198a333b0e
https://doi.org/10.1183/23120541.lsc-2022.42
https://doi.org/10.1183/23120541.lsc-2022.42
Autor:
Carolina Gotera, Alejandra Roncero, Andreas Hoeflich, Christine Höflich, Elvira Alfaro-Arnedo, Germán Peces Barba, Iciar Paula Lopez Garcia, José G. Pichel, Alfredo Urtubia, Carlos Ruíz-Martínez, Marta Canalejo
Publikováno v:
Monitoring airway disease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e21131ce8c193d2f54357406d8b032e
https://doi.org/10.1183/13993003.congress-2021.pa1952
https://doi.org/10.1183/13993003.congress-2021.pa1952
Autor:
Jorge A. Pino, Icíar P. López, Elvira Alfaro-Arnedo, Gema Mondejar-Parreño, Germán Peces-Barba, Javier Sevilla-Montero, Sandra Pérez-Rial, José G. Pichel, C Fernández-Pérez, Bianca Barreira, L Fernández-Blanco, Angel Cogolludo, David Labrousse-Arias, M J Calzada Garcia, Victor I. Peinado
Publikováno v:
Pulmonary hypertension.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcbf626559bc1b0bb51937402e0c66dc
https://doi.org/10.1183/13993003.congress-2021.pa589
https://doi.org/10.1183/13993003.congress-2021.pa589