Výsledky vyhledávání - "Elvia Padilla"

Discovery of GlyT2 Inhibitors Using Structure-Based Pharmacophore Screening and Selectivity Studies by FEP+ Calculations

Autor: Filip Fratev, Ashley Bryan Lopez, Suman Sirimulla, Elvia Padilla, Manuel Miranda-Arango

Publikováno v: ACS Med Chem Lett

[Image: see text] In recent years, mammalian Glycine transporter 2 (GlyT2) has emerged as a promising target for the development of compounds against chronic pain states. In our current work, we discovered a new set of promising hits that inhibit the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3664aa09a99af2877842e7d0e271ad78
https://pubmed.ncbi.nlm.nih.gov/31223446

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Discovery of New Classes of Glycine transporter 2 (GlyT2) Inhibitors and Study of GlyT2 Selectivity by Combination of Novel Structural Based Virtual Screening Approach and Free Energy Perturbation (FEP+) Calculations

Autor: Elvia Padilla, Manuel Miranda-Arango, Filip Fratev, Suman Sirimulla

In recent years, the mammalian GlyT2 transporter have emerged as a promising target for the development of anti-chronic pain agents. In our current work, we discovered a new set of promising hits that inhibit the glycine transport at nano and micromo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59af17ffbfded3478d5a58f87d3d4563
https://doi.org/10.1101/510487

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Elektronická kniha

Las Tejanas : 300 Years of History

Autor: Teresa Palomo Acosta, Ruthe Winegarten

Winner, Texas Reference Source Award, Reference Round Table, Texas Library Association, 2003 T.R. Fehrenbach Award, Texas Historical Commission, 2004 Since the early 1700s, women of Spanish/Mexican origin or descent have played a central, if often un

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