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pro vyhledávání: '"Elva E. Joya"'
Autor:
Lavinia M. Sherrill, Elva E. Joya, AnnMarie Walker, Anuradha Roy, Yousef M. Alhammad, Moriama Atobatele, Sarah Wazir, George Abbas, Patrick Keane, Junlin Zhuo, Anthony K.L. Leung, David K. Johnson, Lari Lehtiö, Anthony R. Fehr, Dana Ferraris
Publikováno v:
bioRxiv
A series of amino acid based7H-pyrrolo[2,3-d]pyrimidines were designed and synthesized to discern the structure activity relationships against the SARS-CoV-2 nsp3 macrodomain (Mac1), an ADP-ribosylhydrolase that is critical for coronavirus replicatio