Výsledky vyhledávání - "Elton Zvinavashe"

Use of category approaches, read-across and (Q)SAR: General considerations

Autor: Grace Patlewicz, Ewan D. Booth, Christa Hennes, Elton Zvinavashe, Etje Hulzebos, Nicholas Ball

Publikováno v: Regulatory Toxicology and Pharmacology. 67:1-12

Read-across has generated much attention since it may be used as an alternative approach for addressing the information requirements under regulatory programmes, notably the EU’s REACH regulation. Read-across approaches are conceptually accepted by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d35b6db5720588c214e3d369ca136f06
https://doi.org/10.1016/j.yrtph.2013.06.002

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Quantitative structure-activity relationship modeling of the toxicity of organothiophosphate pesticides to Daphnia magna and Cyprinus carpio

Autor: Jacques Vervoort, Albertinka J. Murk, Ivonne M.C.M. Rietjens, Tamas Griff, Tingting Du, Elton Zvinavashe, Hans H. J. van den Berg, Ans E. M. F. Soffers

Publikováno v: Chemosphere, 75(11), 1531-1538
Chemosphere 75 (2009) 11

Within the REACH regulatory framework in the EU, quantitative structure-activity relationships (QSAR) models are expected to help reduce the number of animals used for experimental testing. The objective of this study was to develop QSAR models to de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd16cb9098b916252c2f65d17ae16df
https://doi.org/10.1016/j.chemosphere.2009.01.081

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On the number of EINECS compounds that can be covered by (Q)SAR models for acute toxicity

Autor: Ivonne M.C.M. Rietjens, Albertinka J. Murk, Elton Zvinavashe

Publikováno v: Toxicology Letters, 184(1), 67-72
Toxicology Letters 184 (2009) 1

The new EU legislation for managing chemicals called REACH aims to fill in gaps in toxicity information that exist for the chemicals listed on the European Inventory of Existing Chemical Substances (EINECS). REACH advocates the use of alternatives to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff3e718baa86ab95374bc5c8b70af055
https://research.wur.nl/en/publications/on-the-number-of-einecs-compounds-that-can-be-covered-by-qsar-mod

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QSAR models for predicting in vivo aquatic toxicity of chlorinated alkanes to fish

Autor: Elton Zvinavashe, Albertinka J. Murk, Ivonne M.C.M. Rietjens, Andreas Freidig, Ans E. M. F. Soffers, Hans van den Berg, Jacques Vervoort

Publikováno v: Chemical Research in Toxicology, 21(3), 739-745
Chemical Research in Toxicology 21 (2008) 3
Chemical Research in Toxicology, 3, 21, 739-745

Quantitative structure-activity relationship (QSAR) models are expected to play a crucial role in reducing the number of animals to be used for toxicity testing resulting from the adoption of the new European Union chemical control system called Regi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cdd3dd1332812f575889d7d5ed4a7f8
https://pubmed.ncbi.nlm.nih.gov/18254607

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Quantum chemistry based quantitative structure-activity relationships for modeling the (sub)acute toxicity of substituted mononitrobenzenes in aquatic systems

Autor: Jacques Vervoort, Elton Zvinavashe, Andreas Freidig, Albertinka J. Murk, Ans E. M. F. Soffers, Ivonne M.C.M. Rietjens

Publikováno v: Environmental toxicology and chemistry. 25(9)

Fifteen experimental literature data sets on the acute toxicity of substituted nitrobenzenes to algae (Scenedesmus obliquus, Chlorella pyrenoidosa, C. vulgaris), daphnids (Daphnia magna, D. carinata), fish (Cyprinus carpio, Poecilia reticulata), prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7aa6ed1eadb56270d73e803e2b81d4
https://pubmed.ncbi.nlm.nih.gov/16986785

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Disruption of thyroid hormone-mediated Xenopus laevis tadpole tail tip regression by hexabromocyclododecane (HBCD) and 2,2',3,3',4,4',5,5',6-nona brominated diphenyl ether (BDE206)

Autor: John Furlow, Merijn Schriks, Albertinka J. Murk, Elton Zvinavashe

Publikováno v: Chemosphere, 65(10), 1904-1908
Chemosphere 65 (2006) 10

Thyroid hormone regulates amphibian metamorphosis, including the transformation of a tadpole into a froglet and regression of the tail. Xenopus laevis tadpole tail tips in organ culture ( ex vivo ) undergo regression when exposed to 3,3′,5-triiodo-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d2a6053794be54212bfac09f25b61e9
https://research.wur.nl/en/publications/disruption-of-thyroid-hormone-mediated-xenopus-laevis-tadpole-tai

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