Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Elton P. Hudson"'
Autor:
Emil Sporre, Jan Karlsen, Karen Schriever, Johannes Asplund-Samuelsson, Markus Janasch, Linnéa Strandberg, Anna Karlsson, David Kotol, Luise Zeckey, Ilaria Piazza, Per-Olof Syrén, Fredrik Edfors, Elton P. Hudson
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract Metabolite-level regulation of enzyme activity is important for microbes to cope with environmental shifts. Knowledge of such regulations can also guide strain engineering for biotechnology. Here we apply limited proteolysis-small molecule m
Externí odkaz:
https://doaj.org/article/2c6980d3398e4e32bbf83c4737c7e657
Autor:
Lun Yao, Kiyan Shabestary, Sara M. Björk, Johannes Asplund-Samuelsson, Haakan N. Joensson, Michael Jahn, Elton P. Hudson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Developing cyanobacteria as CO2-neutral cell factories relies on the knowledge of the regulation mechanisms for growth and metabolism. Here, the authors develop an inducible CRISPRi gene repression library in Synechocystis sp. PCC 6803 and screens ge
Externí odkaz:
https://doaj.org/article/b347e4caadcb4489961c56c34a9c1a76
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Metabolically engineered cyanobacteria have the potential to mitigate anthropogenic CO2 emissions by converting CO2 into renewable fuels and chemicals. Yet, better understanding of metabolic regulation in cyanobacteria is required to develop more pro
Externí odkaz:
https://doaj.org/article/ffb04a73f6e64d8c8ae78536cd898db7
Publikováno v:
Life, Vol 11, Iss 11, p 1198 (2021)
The use of the versatile cyanobacterial extracellular polymeric substances (EPS) for biotechnological/biomedical applications implies an extensive knowledge of their biosynthetic pathways to improve/control polymer production yields and characteristi
Externí odkaz:
https://doaj.org/article/fe1c7722ca9f44368f281ae8ff61104e
Autor:
Kiyan Shabestary, Elton P. Hudson
Publikováno v:
Metabolic Engineering Communications, Vol 3, Iss , Pp 216-226 (2016)
Chemical and fuel production by photosynthetic cyanobacteria is a promising technology but to date has not reached competitive rates and titers. Genome-scale metabolic modeling can reveal limitations in cyanobacteria metabolism and guide genetic engi
Externí odkaz:
https://doaj.org/article/8b8c9d8efa50469e86b38ad0deba0db7
Publikováno v:
mSystems, Vol 3, Iss 5 (2018)
ABSTRACT Cyanobacteria experience both rapid and periodic fluctuations in light and inorganic carbon (Ci) and have evolved regulatory mechanisms to respond to these, including extensive posttranscriptional gene regulation. We report the first genome-
Externí odkaz:
https://doaj.org/article/a5a6adac20c646c099f0e0ba91b2cceb
Autor:
Michael Jahn, Vital Vialas, Jan Karlsen, Gianluca Maddalo, Fredrik Edfors, Björn Forsström, Mathias Uhlén, Lukas Käll, Elton P. Hudson
Publikováno v:
Cell Reports, Vol 25, Iss 2, Pp 478-486.e8 (2018)
Summary: Cyanobacteria must balance separate demands for energy generation, carbon assimilation, and biomass synthesis. We used shotgun proteomics to investigate proteome allocation strategies in the model cyanobacterium Synechocystis sp. PCC 6803 as
Externí odkaz:
https://doaj.org/article/7e1da3912e534cb2a5fbc7ac557d174e
Autor:
Markus Janasch, Nick Crang, Johannes Asplund-Samuelsson, Emil Sporre, Manuel Bruch, Arvid Gynnå, Michael Jahn, Elton P. Hudson
Publikováno v:
Metabolic Engineering. 73:256-269
The chemolithotroph Cupriavidus necator H16 is known as a natural producer of the bioplastic-polymer PHB, as well as for its metabolic versatility to utilize different substrates, including formate as the sole carbon and energy source. Depending on t
Autor:
Elton P. Hudson
Publikováno v:
Seminars in Cell & Developmental Biology.
Publikováno v:
ACS synthetic biology. 11(9)
Establishing various synthetic biology tools is crucial for the development of cyanobacteria for biotechnology use, especially tools that allow for precise and markerless genome editing in a time-efficient manner. Here, we describe a riboswitch-induc