Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Elso Manghisi"'
Publikováno v:
Tetrahedron. 51:8121-8134
A strategy for the preparation of 4,4-disubstituted-3-amino-2-azetidinones, which are useful intermediates for the synthesis of analogues of monosulfactam Tigemonam, was developed. It employs D-serine as chiral starting material and involves, as key
Publikováno v:
Tetrahedron. 50:11967-11982
A new efficient entry into cis monobactams starting from β -hydroxyesters is reported. This preparation is based on the stereoselective “electrophilic amination” of β-hydroxyester dianions and on Miller's biomimetic synthesis of the β-lactam n
Autor:
Elso Manghisi, Giuseppe Cascio, Enrica Narisano, Luca Banfi, Renata Riva, Chiara Ghiron, Giuseppe Guanti
Publikováno v:
Tetrahedron. 50:11983-11994
Both enantiomers of 4-p-anisyloxy-3-hydroxybutanoates 4 have been prepared in high e.e. by reduction of the corresponding β-ketoesters or β-ketocarboxylates with immobilized fermenting baker's yeast. The utility of these new chiral building blocks
Publikováno v:
ChemInform. 26
A new efficient entry into cis monobactams starting from β -hydroxyesters is reported. This preparation is based on the stereoselective “electrophilic amination” of β-hydroxyester dianions and on Miller's biomimetic synthesis of the β-lactam n
Autor:
Luca Banfi, Chiara Ghiron, Giuseppe Guanti, Giuseppe Cascio, Elso Manghisi, Renata Riva, Enrica Narisano
Publikováno v:
ChemInform. 26
Both enantiomers of 4-p-anisyloxy-3-hydroxybutanoates 4 have been prepared in high e.e. by reduction of the corresponding β-ketoesters or β-ketocarboxylates with immobilized fermenting baker's yeast. The utility of these new chiral building blocks
Publikováno v:
ChemInform. 26
Autor:
Giuseppe Cascio, R. Sperning, Giuseppe Satta, Grazia Angela Morandotti, Elso Manghisi, Renata Riva, Giuseppe Guanti
Publikováno v:
ChemInform. 29
A new series of monobactam derivatives, bearing unsubstituted or N-monosubstituted sulfamoyloxymethyl groups in position 4 was synthesized either in racemic or in optically active form. Their in vitro antibacterial activity was tested in comparison w
Autor:
R. Sperning, Grazia Angela Morandotti, Giuseppe Cascio, Giuseppe Satta, Renata Riva, Elso Manghisi, Giuseppe Guanti
Publikováno v:
Farmaco (Societa chimica italiana : 1989). 53(3)
A new series of monobactam derivatives, bearing unsubstituted or N-monosubstituted sulfamoyloxymethyl groups in position 4 was synthesized either in racemic or in optically active form. Their in vitro antibacterial activity was tested in comparison w
Publikováno v:
ChemInform. 21
A series of new 4-aryl-5-[omega-(4-aryl-1-piperazinyl)alkyl]-2(3H)- oxazolones was synthesized and tested for neuroleptic activity in mice and rats. Several compounds exhibited interesting neuroleptic activity with very low liability to the extrapyra
Publikováno v:
Journal of Heterocyclic Chemistry. 25:943-947
A new route to 2-substituted-2,3-dihydro-2-hydroxymethyl-1,4-benzodioxins 3 based on the reaction of α-(2-hydroxyphenoxy)alkylketones 1 with dimethylsulphoxonium methylide in dimethylsulphoxide is reported. Besides the desired compounds 3, the isome