Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Elsie M. B. Sorensen"'
Autor:
Elsie M. B. Sorensen
Publikováno v:
Toxicology Letters. 45:101-110
Morphometric analysis was used to quantitate indomethacin-induced morphological changes in primary cultures of neonatal rat hepatocytes by comparison with standard assessments of functional integrity (i.e. enzyme release, urea levels, and dye exclusi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d70591c99bb1d05e88d4b37471dcacc
https://doi.org/10.1016/0378-4274(89)90164-1
https://doi.org/10.1016/0378-4274(89)90164-1
Autor:
Thomas L. Bauer, Elsie M. B. Sorensen
Publikováno v:
Environmental Pollution Series A, Ecological and Biological. 34:357-366
To monitor the biological impact of chronic, low-level selenium exposure, redear sunfish Lepomis microlophus were collected from various locations in Martin Lake which had received discharges of selenium-containing wastes from an electrical generatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbe0d467d83a604e9c00c4db38081aee
https://doi.org/10.1016/0143-1471(84)90113-2
https://doi.org/10.1016/0143-1471(84)90113-2
Autor:
Elsie M. B. Sorensen
Publikováno v:
Toxicology Letters. 34:277-286
This study was undertaken to quantitate morphological changes in primary cultures of liver cells exposed to benoxaprofen and to compare morphological assessments with standard assessments of functional integrity. Rat hepatocytes were exposed for 12 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::992116437b0ba7d4f1c471abd49d9d9d
https://doi.org/10.1016/0378-4274(86)90220-1
https://doi.org/10.1016/0378-4274(86)90220-1
Publikováno v:
Journal of Tissue Culture Methods. 9:11-17
Steady-state fluorescence polarization of 1,6-diphenyl-1,3,5-hexatriene (DPH) incorporated into plasma membranes of parenchymal hepatocytes provides a simple method of monitoring the immediate interactions of divalent cations with these membranes. Ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40ecf5e6df73270d47b1c503b1a38fdd
https://doi.org/10.1007/bf01666039
https://doi.org/10.1007/bf01666039
Publikováno v:
Bulletin of Environmental Contamination and Toxicology. 22:617-624
In previous work to increase the effectiveness of unesterified DTPA for removal of actinides, the dibutyl ester of DTPA (Bu/sub 2/DTPA) was synthesized. Because this molecule has a reduced charge and increased lipid solubility compared to either EDTA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb5df4266733d23aae650025e0f91a02
https://doi.org/10.1007/bf02026997
https://doi.org/10.1007/bf02026997
Autor:
Daniel Acosta, Elsie M. B. Sorensen
Publikováno v:
Journal of Toxicology and Environmental Health. 16:425-440
Primary cultures of intact, functional heptocytes were used to compare the relative toxicity of four nonsteroid antiinflammatory agents (NSAID)--benoxaprofen, orpanoxin, aspirin, and ibuprofen--with that of indomethacin. The relative toxicity of thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01670f99d9a5713535c33797ba137d05
https://doi.org/10.1080/15287398509530752
https://doi.org/10.1080/15287398509530752
Publikováno v:
Archives of Environmental Contamination and Toxicology. 11:469-473
Adult green sunfish were exposed to aqueous solutions of arsenic as sodium arsenate and sacrificed at regular intervals for morphological and analytical procedures including scanning transmission electron microscopy (STEM), electron probe X-ray micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d984722e69cf24ea772868ddb513c914
https://doi.org/10.1007/bf01056074
https://doi.org/10.1007/bf01056074
Publikováno v:
Toxicology Letters. 25:319-326
The fluidity of plasma membranes was assessed by steady-state fluorescence polarization of 1,6-diphenyl-1,3,5-hexatriene (DPH), a fluorescent probe. The presence of increasing concentrations of calcium (Ca) (0.5–4 mM), cadmium (Cd) (50–500 μM),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de29471d9889c268e6f49779554ff78
https://doi.org/10.1016/0378-4274(85)90214-0
https://doi.org/10.1016/0378-4274(85)90214-0
Autor:
Elsie M. B. Sorensen, Daniel Acosta
Publikováno v:
Toxicology Letters. 27:73-82
Primary cultures of rat hepatocytes were exposed to several concentrations of erythromycin estolate (EE). Hepatotoxicity was evaluated using lactate dehydrogenase (LDH) leakage and morphometric analysis of representative populations of cells examined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f4e7d215c9a848c3ba11f0f9283a877
https://doi.org/10.1016/0378-4274(85)90122-5
https://doi.org/10.1016/0378-4274(85)90122-5
Comparison of Dantrolene Sodium with Erythromycin Estolate Using Primary Cultures of Rat Hepatocytes
Autor:
Daniel Acosta, Elsie M. B. Sorensen
Publikováno v:
Drug and Chemical Toxicology. 8:219-237
Using primary cultures of parenchymal hepatocytes as a model system, the cytotoxic potential of dantrolene sodium (DS) was compared with that of erythromycin estolate (EE)--a known hepatotoxin. Parallel morphological and functional comparisons were m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e15369ed4faa84bc80619af3883b471
https://doi.org/10.3109/01480548509038647
https://doi.org/10.3109/01480548509038647