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of 11
pro vyhledávání: '"Elsie M. Allen"'
Autor:
Sharon Wilson, Charles D. Howell, Elsie M. Allen, Paul C. Kuo, Lynt B. Johnson, Jacqueline Laurin, Archana Shetty
Publikováno v:
Transplantation. 69:2451-2454
BACKGROUND Thirty-five percent to 80% of cirrhotic patients have impaired glucose tolerance (IGT) or diabetes mellitus (DM). Diabetic cirrhotics have higher morbidity and mortality than nondiabetics. Therefore, it would be worthwhile to determine whe
Publikováno v:
Autoimmunity. 32:229-240
Cytokines modulate the course of autoimmunity, but their role in the evolution of spontaneous disease is unclear. This study compared the cytokine kinetics of T cell cultures from thyroiditis (LT)-prone NB line BB/Wor rats with those of Wistar (Wis)
Autor:
Stephen T. Bartlett, Elsie M. Allen
Publikováno v:
Transplantation. 68:25-30
Background: BB/Wor rats develop spontaneous autoimmune insulin-requiring diabetes mellitus and lymphocytic thyroiditis (LT). Our investigations examined the effect of the thyroid-specific agents, iodine and methimazole (MMI) on thyroid graft survival
Autor:
Elsie M. Allen, Lewis E. Braverman
Publikováno v:
Endocrinology. 127:1613-1616
Excess iodine has been associated with an increased incidence of lymphocytic thyroiditis (LT) in the BB/W rat, obese strain chicken, and hamster. The spontaneous incidence of LT in the Buffalo (Buf) rat is increased by neonatal thymectomy. In the pre
Autor:
Wen Chi Hsueh, Paul W. Ladenson, Braxton D. Mitchell, Mona M. Sabra, Toni I. Pollin, Alan R. Shuldiner, Kristi D. Silver, Elsie M. Allen
Publikováno v:
The Journal of clinical endocrinology and metabolism. 88(3)
Autoimmune thyroiditis (AITD) is a common disorder characterized by circulating antibodies to epitopes of thyroid tissue and hypothyroidism (Hashimoto's thyroiditis or AITD-hypothyroidism), although many subjects with AITD are euthyroid. Current evid
Autor:
Elsie M. Allen
Publikováno v:
Journal of endocrinological investigation. 16(4)
In genetically predisposed individuals, autoimmune lymphocytic thyroiditis (LT) is potentiated by excess dietary iodine (I). There have been data which suggest that oxidative stress may have a role in iodine-induced LT. These in vivo studies were und
Publikováno v:
Acta Endocrinologica. 116:S70-S76
Spontaneous LT and elevated serum anti-Tg occur in the diabetes prone BB/W rat, but thyroid function is essentially normal in the rats with LT. Prolonged low dose MMI decreases the incidence of LT in BB/W rats. The administration of excess iodine beg
Autor:
Sharon Alex, Walter Reinhardt, Appel Michael C, Lewis E. Braverman, Terri L. Paul, Elsie M. Allen, Yong-Nian Yang
Publikováno v:
Endocrinology. 122:1179-1181
Chronic L-thyroxine administration (6 micrograms/100g BW, ip, daily) for 2 or 3 months suppressed serum TSH concentrations and decreased both the incidence of spontaneous lymphocytic thyroiditis (LT) and the serum levels of anti-thyroglobulin (anti-T
Publikováno v:
Endocrinology. 118(5)
It has been suggested that the incidence of Hashimoto's thyroiditis is increased in the presence of high iodide intake. The diabetes-prone BB/W rat develops spontaneous histological autoimmune lymphocytic thyroiditis (LT) without functional hypothyro
Publikováno v:
Endocrinology. 121(2)
We have recently reported that iodine administration (0.05% iodine in drinking water) to weanling, diabetes mellitus- and lymphocytic thyroiditis (LT)-prone Biobreeding Worcester (BB/W) rats strikingly increases the incidence of LT without occurrence