Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Elshimaa M. N. Abdelhafez"'
Autor:
Aya Soudi, Onur Bender, Ismail Celik, Amer Ali Abd El-Hafeez, Rumeysa Dogan, Arzu Atalay, Eslam B. Elkaeed, Aisha A. Alsfouk, Elshimaa M. N. Abdelhafez, Omar M. Aly, Wolfgang Sippl, Taha F. S. Ali
Publikováno v:
Pharmaceuticals, Vol 17, Iss 5, p 659 (2024)
Protein kinases regulate cellular activities and make up over 60% of oncoproteins and proto-oncoproteins. Among these kinases, FLT3 is a member of class III receptor tyrosine kinase family which is abundantly expressed in individuals with acute leuke
Externí odkaz:
https://doaj.org/article/56f37112a74842d3a69e8d674c6d9fe3
Autor:
Samar A. El-Kalyoubi, Hesham A. M. Gomaa, Elshimaa M. N. Abdelhafez, Mohamed Ramadan, Fatimah Agili, Bahaa G. M. Youssif
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 716 (2023)
The investigation of novel EGFR and BRAFV600E dual inhibitors is intended to serve as targeted cancer treatment. Two sets of purine/pteridine-based derivatives were designed and synthesized as EGFR/BRAFV600E dual inhibitors. The majority of the compo
Externí odkaz:
https://doaj.org/article/04089e050b4e41e8bbe9bf17f6281d12
Autor:
Ashraf A. Aly, Stefan Bräse, Alaa A. Hassan, Nasr K. Mohamed, Lamiaa E. Abd El-Haleem, Martin Nieger, Nesrin M. Morsy, Mohammed B. Alshammari, Mahmoud A. A. Ibrahim, Elshimaa M. N. Abdelhafez
Publikováno v:
Molecules, Vol 25, Iss 23, p 5569 (2020)
Three new series of paracyclophanyl-dihydronaphtho[2,3-d]thiazoles and paracyclophanyl-thiazolium bromides were designed, synthesized, and characterized by their spectroscopic data, along with X-ray analysis. One-dose assay results of anticancer acti
Externí odkaz:
https://doaj.org/article/9b2e66ca32ae4cb29cca92863f5ab49c
Autor:
Essmat M. El-Sheref, Ashraf A. Aly, Mohammed B. Alshammari, Alan B. Brown, Sara Mohamed Naguib Abdel-Hafez, Walaa Yehia Abdelzaher, Stefan Bräse, ElShimaa M. N. Abdelhafez
Publikováno v:
Molecules, Vol 25, Iss 21, p 5057 (2020)
A series of novel 1,2,3-triazoles hybridized with two quinolin-2-ones, was designed and synthesized through click reactions. The structures of the synthesized compounds were elucidated by NMR, IR, and mass spectra in addition to elemental analysis. T
Externí odkaz:
https://doaj.org/article/61db7afaa2ec412388ba8fb8bb73cb8f
Autor:
Ashraf A Aly, Stefan Bräse, Alaa A. Hassan, Nasr K. Mohamed, Lamiaa E. Abd El-Haleem, Martin Nieger, Nesrin M. Morsy, Elshimaa M. N. Abdelhafez
Publikováno v:
Molecules, Vol 25, Iss 13, p 3089 (2020)
A new series of methyl 2-(2-(4′-[2.2]paracyclophanyl)-hydrazinylidene)-3-substituted-4-oxothiazolidin-5-ylidene)acetates 3a–f were synthesized from the reaction of paracyclophanyl-acylthiosemicarbazides 2a–f with dimethyl acetylenedicarboxylate
Externí odkaz:
https://doaj.org/article/4b57b26bfde943308653d4096fbd462b
Autor:
Asmaa H. Mohamed, Sara M. Mostafa, Ashraf A. Aly, Alaa A. Hassan, Esraa M. Osman, AbdElAziz A. Nayl, Alan B. Brown, Elshimaa M. N. Abdelhafez
Publikováno v:
RSC Advances. 13:14631-14640
In an attempt to develop effective and safe antibacterial agents, thiazinanones bearing the quinolone scaffold were prepared by reaction of the corresponding (quinolinylmethylene)hydrazinecarbothioamides with 2,3-diphenylcycloprop-2-enone.
Autor:
Muhamad Mustafa, Yaser A. Mostafa, Atef E. Abd Elbaky, Mahmoud Mohamed, Dalia Abdelhamid, ElShimaa M. N. Abdelhafez, Omar Aly
Publikováno v:
Octahedron Drug Research.