Development of Customizable Implementation Guides to Support Clinical Adoption of Pharmacogenomics: Experiences of the Implementing GeNomics In pracTicE (IGNITE) Network

Autor: Duong BQ, Arwood MJ, Hicks JK, Beitelshees AL, Franchi F, Houder JT, Limdi NA, Cook KJ, Owusu Obeng A, Petry N, Tuteja S, Elsey AR, Cavallari LH, Wiisanen K

Publikováno v: Pharmacogenomics and Personalized Medicine, Vol Volume 13, Pp 217-226 (2020)

Benjamin Q Duong,1 Meghan J Arwood,2 J Kevin Hicks,3 Amber L Beitelshees,4 Francesco Franchi,5 John T Houder,2 Nita A Limdi,6 Kelsey J Cook,7,8 Aniwaa Owusu Obeng,9 Natasha Petry,10 Sony Tuteja,11 Amanda R Elsey,2 Larisa H Cavallari,2 Kristin Wiisane

Externí odkaz: https://doaj.org/article/7e21adca8a2f4393a79bf71ddb7097df

Strategies to Integrate Genomic Medicine into Clinical Care: Evidence from the IGNITE Network.

Autor: Sperber NR; Duke Department of Population Health Sciences, Duke University School of Medicine, Durham, NC 27701, USA.; Durham VA Health Care System, Durham, NC 27705, USA.; Center for Applied Genomics & Precision Medicine, Duke University School of Medicine, Durham, NC 27708, USA., Dong OM; Center for Applied Genomics & Precision Medicine, Duke University School of Medicine, Durham, NC 27708, USA., Roberts MC; Division of Pharmaceutical Outcomes and Policy, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Dexter P; Regenstrief Institute, Indianapolis, Indiana University School of Medicine and Clem McDonald Center for Biomedical Informatics, Indianapolis, IN 46202, USA., Elsey AR; Center for Pharmacogenomics and Precision Medicine, Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, FL 32610, USA., Ginsburg GS; Center for Applied Genomics & Precision Medicine, Duke University School of Medicine, Durham, NC 27708, USA., Horowitz CR; Institute for Health Equity Research, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Johnson JA; Center for Pharmacogenomics and Precision Medicine, Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, FL 32610, USA., Levy KD; Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, 950 W. Walnut Street, Indianapolis, IN 46202, USA., Ong H; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Peterson JF; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Pollin TI; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Rakhra-Burris T; Center for Applied Genomics & Precision Medicine, Duke University School of Medicine, Durham, NC 27708, USA., Ramos MA; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Skaar T; Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, 950 W. Walnut Street, Indianapolis, IN 46202, USA., Orlando LA; Center for Applied Genomics & Precision Medicine, Duke University School of Medicine, Durham, NC 27708, USA.

Publikováno v: Journal of personalized medicine [J Pers Med] 2021 Jul 08; Vol. 11 (7). Date of Electronic Publication: 2021 Jul 08.

Design and Early Implementation Successes and Challenges of a Pharmacogenetics Consult Clinic.

Autor: Arwood MJ; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, 1345 Center Dr, Gainesville, FL 32603, USA.; Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, 1345 Center Dr, Gainesville, FL 32603, USA., Dietrich EA; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, 1345 Center Dr, Gainesville, FL 32603, USA., Duong BQ; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, 1345 Center Dr, Gainesville, FL 32603, USA.; Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, 1345 Center Dr, Gainesville, FL 32603, USA., Smith DM; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, 1345 Center Dr, Gainesville, FL 32603, USA.; Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, 1345 Center Dr, Gainesville, FL 32603, USA., Cook K; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, 1345 Center Dr, Gainesville, FL 32603, USA.; Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, 1345 Center Dr, Gainesville, FL 32603, USA., Elchynski A; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, 1345 Center Dr, Gainesville, FL 32603, USA.; Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, 1345 Center Dr, Gainesville, FL 32603, USA., Rosenberg EI; Division of General Internal Medicine, College of Medicine, University of Florida, 1329 SW 16th St, Gainesville, FL 32608, USA., Huber KN; Division of General Internal Medicine, College of Medicine, University of Florida, 1329 SW 16th St, Gainesville, FL 32608, USA., Nagoshi YL; Division of General Internal Medicine, College of Medicine, University of Florida, 1329 SW 16th St, Gainesville, FL 32608, USA., Wright A; Division of General Internal Medicine, College of Medicine, University of Florida, 1329 SW 16th St, Gainesville, FL 32608, USA., Budd JT; Division of General Internal Medicine, College of Medicine, University of Florida, 1329 SW 16th St, Gainesville, FL 32608, USA., Holland NP; Division of General Internal Medicine, College of Medicine, University of Florida, 1329 SW 16th St, Gainesville, FL 32608, USA., Maska E; Division of General Internal Medicine, College of Medicine, University of Florida, 1329 SW 16th St, Gainesville, FL 32608, USA., Panna D; Division of General Internal Medicine, College of Medicine, University of Florida, 1329 SW 16th St, Gainesville, FL 32608, USA., Elsey AR; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, 1345 Center Dr, Gainesville, FL 32603, USA.; Clinical and Translational Science Institute, University of Florida, 2004 Mowry Rd, Gainesville, FL 32610, USA., Cavallari LH; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, 1345 Center Dr, Gainesville, FL 32603, USA.; Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, 1345 Center Dr, Gainesville, FL 32603, USA., Wiisanen K; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, 1345 Center Dr, Gainesville, FL 32603, USA.; Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, 1345 Center Dr, Gainesville, FL 32603, USA., Johnson JA; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, 1345 Center Dr, Gainesville, FL 32603, USA.; Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, 1345 Center Dr, Gainesville, FL 32603, USA., Gums JG; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, 1345 Center Dr, Gainesville, FL 32603, USA.

Publikováno v: Journal of clinical medicine [J Clin Med] 2020 Jul 17; Vol. 9 (7). Date of Electronic Publication: 2020 Jul 17.

CYP2D6-guided opioid therapy improves pain control in CYP2D6 intermediate and poor metabolizers: a pragmatic clinical trial.

Autor: Smith DM; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA., Weitzel KW; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA.; Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, FL, USA., Elsey AR; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA.; Clinical and Translational Science Institute, University of Florida, Gainesville, FL, USA., Langaee T; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA.; Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, FL, USA., Gong Y; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA.; Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, FL, USA., Wake DT; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA., Duong BQ; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA., Hagen M; Division of General Internal Medicine, College of Medicine, University of Florida, Gainesville, FL, USA., Harle CA; Department of Health Policy and Management, Indiana University, Indianapolis, IN, USA., Mercado E; Department of Community Health and Family Medicine, College of Medicine, University of Florida, Gainesville, FL, USA., Nagoshi Y; Division of General Internal Medicine, College of Medicine, University of Florida, Gainesville, FL, USA., Newsom K; University of Florida Health Pathology Laboratories, Gainesville, FL, USA., Wright A; Division of General Internal Medicine, College of Medicine, University of Florida, Gainesville, FL, USA., Rosenberg EI; Division of General Internal Medicine, College of Medicine, University of Florida, Gainesville, FL, USA., Starostik P; University of Florida Health Pathology Laboratories, Gainesville, FL, USA.; Department of Pathology, Immunology & Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA., Clare-Salzler MJ; University of Florida Health Pathology Laboratories, Gainesville, FL, USA., Schmidt SO; Department of Community Health and Family Medicine, College of Medicine, University of Florida, Gainesville, FL, USA., Fillingim RB; Clinical and Translational Science Institute, University of Florida, Gainesville, FL, USA.; Department of Community Dentistry and Behavioral Science, College of Dentistry, Gainesville, FL, USA., Johnson JA; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA.; Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, FL, USA.; Clinical and Translational Science Institute, University of Florida, Gainesville, FL, USA., Cavallari LH; Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA. lcavallari@cop.ufl.edu.; Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, FL, USA. lcavallari@cop.ufl.edu.; Clinical and Translational Science Institute, University of Florida, Gainesville, FL, USA. lcavallari@cop.ufl.edu.

Publikováno v: Genetics in medicine : official journal of the American College of Medical Genetics [Genet Med] 2019 Aug; Vol. 21 (8), pp. 1842-1850. Date of Electronic Publication: 2019 Jan 23.

Clinical implementation of rapid CYP2C19 genotyping to guide antiplatelet therapy after percutaneous coronary intervention.

Autor: Cavallari LH; Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, FL, USA. lcavallari@cop.ufl.edu.; Center for Pharmacogenomics, University of Florida, Gainesville, FL, USA. lcavallari@cop.ufl.edu.; Clinical and Translational Science Institute, University of Florida, Gainesville, FL, USA. lcavallari@cop.ufl.edu., Franchi F; Division of Cardiology, Department of Medicine, University of Florida, Jacksonville, FL, USA., Rollini F; Division of Cardiology, Department of Medicine, University of Florida, Jacksonville, FL, USA., Been L; Division of Cardiology, Department of Medicine, University of Florida, Jacksonville, FL, USA., Rivas A; Division of Cardiology, Department of Medicine, University of Florida, Jacksonville, FL, USA., Agarwal M; Division of Cardiology, Department of Medicine, University of Florida, Jacksonville, FL, USA., Smith DM; Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, FL, USA.; Center for Pharmacogenomics, University of Florida, Gainesville, FL, USA., Newsom K; University of Florida Health Pathology Laboratories, Gainesville, FL, USA., Gong Y; Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, FL, USA.; Center for Pharmacogenomics, University of Florida, Gainesville, FL, USA., Elsey AR; Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, FL, USA.; Clinical and Translational Science Institute, University of Florida, Gainesville, FL, USA., Starostik P; University of Florida Health Pathology Laboratories, Gainesville, FL, USA.; Department of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL, USA., Johnson JA; Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, FL, USA.; Center for Pharmacogenomics, University of Florida, Gainesville, FL, USA.; Clinical and Translational Science Institute, University of Florida, Gainesville, FL, USA., Angiolillo DJ; Division of Cardiology, Department of Medicine, University of Florida, Jacksonville, FL, USA.

Publikováno v: Journal of translational medicine [J Transl Med] 2018 Apr 11; Vol. 16 (1), pp. 92. Date of Electronic Publication: 2018 Apr 11.