Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Elsebeth Andersen"'
Autor:
Christian Beerli, Thai Than, Joanne Joergensen, Andrea Florineth, Gisbert Weckbecker, Anette Von Matt, Christos Papageorgiou, Xaver Borer, Elsebeth Andersen, Gretty Rihs, Christoph Heusser, Max H. Schreier, Katrin Wagner
Publikováno v:
Journal of Medicinal Chemistry. 44:1986-1992
The prevention of xenograft rejection is substantially dependent on inhibiting antibodies (Ab) produced by B-cells independently of T-cell signals (TI-1). Due to their ubiquitous biochemical mechanisms of action, the immunosuppressants currently empl
Publikováno v:
Neuroscience Letters. 263:65-68
Most cases of early onset familial Alzheimer's disease (FAD) involve mutations in presenilins (PS1 and PS2) genes. The C-terminal portion of PS2 is a homologue with an apoptosis-linked gene (ALG-3). To characterise the role of PS1 in apoptosis, we ov
Autor:
Hans Peter Weber, Valerie Hungerford, Elsebeth Andersen, Francis Bitch, Christos Papageorgiou, Max H. Schreier, Rainer Albert, Michel Lemaire, Philipp Floersheim
Publikováno v:
Journal of Medicinal Chemistry. 41:3530-3538
T-cell immunosuppressant-based therapies efficiently control early graft rejection in allotransplantation settings. They fail, however, to prevent those rejection events which are mediated by transplant-induced antibody (Ab) responses such as those i
Autor:
Peter Hiestand, Max H. Schreier, Elsebeth Andersen, Roland H. Wenger, Valérie F. J. Quesniaux, Götz Baumann, Gerhard Zenke
Publikováno v:
Annals of the New York Academy of Sciences. 685:330-335
Despite the successful clinical application of the immunosuppressive drug cyclosporin A (CsA, Sandimmun), its precise mechanism of action in the process of T cell activation remains elusive. CsA binds to the high-affinity cytosolic receptor cyclophil
Autor:
Philipp Floersheim, Rainer Albert, Max H. Schreier, Valerie Hungerford, Elsebeth Andersen, C Papageorgiou, M Zurini
Publikováno v:
Transplantation Proceedings. 33:2263-2265
Autor:
Rainer Albert, Elsebeth Andersen, Michel Lemaire, Hans Peter Weber, Francis Bitch, Christos Papageorgiou, Philipp Floersheim, Valerie Hungerford, Max H. Schreier
Publikováno v:
ChemInform. 29
T-cell immunosuppressant-based therapies efficiently control early graft rejection in allotransplantation settings. They fail, however, to prevent those rejection events which are mediated by transplant-induced antibody (Ab) responses such as those i
Autor:
Roland H. Wenger, Peter Hiestand, Elsebeth Andersen, Götz Baumann, Gerhard Zenke, Max H. Schreier, Valérie F. J. Quesniaux
Publikováno v:
Journal of Autoimmunity. 5:67-72
The immunosuppressive drug cyclosporin A (CsA, Sandimmun, SIM) is currently being evaluated in a variety of autoimmune disorders with some remarkable successes. Despite the wide empiric application of CsA, the precise mechanism of action of this drug
Autor:
Elsebeth Andersen, Ulrike Strittmatter, R. Tees, Hans P. Kocher, Gerhard Zenke, Max H. Schreier, Barbara Fagg
Publikováno v:
Journal of Immunoassay. 12:185-206
A sensitive and specific two-site ELISA was developed for human granulocyte—macrophage colony-stimulating factor (huGM-CSF) based on monoclonal antibodies (mAbs) which have been selected for high affinities and different epitope specificities. Usin
Autor:
Max H. Schreier, Christos Papageorgiou, Valerie Hungerford, Hellmut Knecht, Elsebeth Andersen, Rainer Albert
Publikováno v:
Bioorganicmedicinal chemistry letters. 8(16)
A library of thioamide derivatives of leflunomide 1a and of its bioactive metabolite 1b has been synthesised on solid phase. Thus, para-substituted phenylacetic acids were coupled to TentaGel and were subsequently reacted with aromatic isothiocyanate
Autor:
Elsebeth Andersen, Götz Baumann, Thomas Schäfer, Frank Brombacher, Claude Tschopp, Kurt Bürki, Ulrike Weissenstein
Publikováno v:
International immunology. 6(2)
A transgenic mouse system has been established to follow the pattern of IL-2 expression at the level of single T cells. This was achieved by introducing a human IL-2 promoter-driven reporter gene (Escherichia coli lacZ) into the germline of mice and