Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Elsayed M. Abdelwhab"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract As immunohistochemistry is valuable for determining tissue and cell tropism of avian influenza viruses (AIV), but time-consuming, an artificial intelligence-based workflow was developed to automate the AIV antigen quantification. Organ sampl
Externí odkaz:
https://doaj.org/article/d30b247122d045829a6b3d904d51f520
Autor:
Luise Hohensee, David Scheibner, Alexander Schäfer, Holly Shelton, Thomas C. Mettenleiter, Angele Breithaupt, Anca Dorhoi, Elsayed M. Abdelwhab, Ulrike Blohm
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-17 (2024)
Abstract Avian influenza viruses (AIV) of the H7N7 subtype are enzootic in the wild bird reservoir in Europe, cause infections in poultry, and have sporadically infected humans. The non-structural protein PB1-F2 is encoded in a second open frame in t
Externí odkaz:
https://doaj.org/article/fe4ccd2d89884908bf60643b5731c604
Publikováno v:
Virulence, Vol 15, Iss 1 (2024)
The economic losses caused by high pathogenicity (HP) avian influenza viruses (AIV) in the poultry industry worldwide are enormous. Although chickens and turkeys are closely related Galliformes, turkeys are thought to be a bridging host for the adapt
Externí odkaz:
https://doaj.org/article/dee406db2ab44e96944529e5ae0f8102
Autor:
Luise Hohensee, David Scheibner, Christine Luttermann, Holly Shelton, Anca Dorhoi, Elsayed M. Abdelwhab, Ulrike Blohm
Publikováno v:
Virus Research, Vol 349, Iss , Pp 199444- (2024)
Avian influenza viruses (AIV) pose a continuous challenge to global health and economy. While countermeasures exist to control outbreaks in poultry, the persistent circulation of AIV in wild aquatic and shorebirds presents a significant challenge to
Externí odkaz:
https://doaj.org/article/94ac0699234b4f198847010dcc06f20c
Autor:
Marcel Gischke, Ola Bagato, Angele Breithaupt, David Scheibner, Claudia Blaurock, Melina Vallbracht, Axel Karger, Beate Crossley, Jutta Veits, Eva Böttcher-Friebertshäuser, Thomas C. Mettenleiter, Elsayed M. Abdelwhab
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 666-678 (2021)
To date, only low pathogenic (LP) H5 and H7 avian influenza viruses (AIV) have been observed to naturally shift to a highly pathogenic (HP) phenotype after mutation of the monobasic hemagglutinin (HA) cleavage site (HACS) to polybasic motifs. The LPA
Externí odkaz:
https://doaj.org/article/6ce905d0851a4206b81dab801d2c15f7
Publikováno v:
Viruses, Vol 15, Iss 4, p 980 (2023)
Influenza viruses belong to the family Orthomyxoviridae with a negative-sense, single-stranded segmented RNA genome. They infect a wide range of animals, including humans. From 1918 to 2009, there were four influenza pandemics, which caused millions
Externí odkaz:
https://doaj.org/article/d1a3d14c164b41e1a98a999bc577fd5d
Autor:
Claudia Blaurock, Ulrike Blohm, Christine Luttermann, Julia Holzerland, David Scheibner, Alexander Schäfer, Allison Groseth, Thomas C. Mettenleiter, Elsayed M. Abdelwhab
Publikováno v:
Emerging Microbes and Infections, Vol 10, Iss 1, Pp 1760-1776 (2021)
Avian influenza viruses (AIV) H5N8 clade 2.3.4.4 pose a public health threat but the viral factors relevant for its potential adaptation to mammals are largely unknown. The non-structural protein 1 (NS1) of influenza viruses is an essential interfero
Externí odkaz:
https://doaj.org/article/c436e6b0a5fb428c811db2df35764c38
Publikováno v:
BMC Veterinary Research, Vol 15, Iss 1, Pp 1-7 (2019)
Abstract Background There is paucity of data on the virulence of highly pathogenic (HP) avian influenza viruses (AIV) H7 in ducks compared to HPAIV H5. Here, the virulence of HPAIV H7N1 (designated H7N1-FPV34 and H7N1-It99) and H7N7 (designated H7N7-
Externí odkaz:
https://doaj.org/article/4aa6b550b58b4bc7b37dcf8214d85972
Autor:
Ahmed H. Salaheldin, Ahmed R. Elbestawy, Abdelkader M. Abdelkader, Hesham A. Sultan, Awad A. Ibrahim, Hatem S. Abd El-Hamid, Elsayed M. Abdelwhab
Publikováno v:
Viruses, Vol 14, Iss 7, p 1431 (2022)
The global spread of avian influenza virus (AIV) of clade 2.3.4.4b since 2016 has caused severe losses in wild birds and poultry and has posed a risk for the infection of mammals including humans. The vaccination of poultry has been used to limit the
Externí odkaz:
https://doaj.org/article/dea38175a8d94b2ea08963e7e964c910
Autor:
Annika Graaf, Reiner Ulrich, Pavlo Maksimov, David Scheibner, Susanne Koethe, Elsayed M. Abdelwhab, Thomas C. Mettenleiter, Martin Beer, Timm Harder
Publikováno v:
Emerging Microbes and Infections, Vol 7, Iss 1, Pp 1-12 (2018)
Abstract Highly pathogenic avian influenza virus (HPAIV) infection in poultry caused devastating mortality and economic losses. HPAIV of subtypes H5 and H7 emerge from precursor viruses of low pathogenicity (LP) by spontaneous mutation associated wit
Externí odkaz:
https://doaj.org/article/d188cc9cf5da4e2b8c0d77866c0fe0fa