Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Elsalem, Lina"'
Autor:
Vinader, Victoria, Sadiq, Maria, Sutherland, Mark, Huang, M.Y., Loadman, Paul, Elsalem, Lina M.I., Shnyder, Steven, Cui, H.J., Afarinkia, Kamyar, Searcey, M., Patterson, Laurence H., Pors, Klaus
Yes
A deactivated alkene precursor (IC50=81 mu M) to the azinomycin epoxide natural product can be bioactivated by several cytochromes P450 (CYP) to generate antiproliferative metabolites with increased potency (IC50=1-30 mu M) in CHOwt cells. C
A deactivated alkene precursor (IC50=81 mu M) to the azinomycin epoxide natural product can be bioactivated by several cytochromes P450 (CYP) to generate antiproliferative metabolites with increased potency (IC50=1-30 mu M) in CHOwt cells. C
Externí odkaz:
http://hdl.handle.net/10454/9419
Autor:
Sheldrake, Helen M., Travica, S., Johansson, I., Loadman, Paul, Sutherland, Mark, Elsalem, Lina M.I., Illingworth, Nicola A., Cresswell, Alexander J., Reuillon, Tristan, Shnyder, Steven, Mkrtchian, S., Searcey, M., Ingelman-Sundberg, M., Patterson, Laurence H., Pors, Klaus
Yes
A library of duocarmycin bioprecursors based on the CPI and CBI scaffolds was synthesized and used to probe selective activation by cells expressing CYP1A1 and 2W1, CYPs known to be expressed in high frequency in some tumors. Several CPI-bas
A library of duocarmycin bioprecursors based on the CPI and CBI scaffolds was synthesized and used to probe selective activation by cells expressing CYP1A1 and 2W1, CYPs known to be expressed in high frequency in some tumors. Several CPI-bas
Externí odkaz:
http://hdl.handle.net/10454/9998
Autor:
Al-U’datt, Doa’a G.F., Alu’datt, Muhammad H., Tranchant, Carole C., Al-Dwairi, Ahmed, Al-shboul, Othman, Almajwal, Ali, Elsalem, Lina, Jaradat, Saied, Alzoubi, Karem H., Faleh, Belal G., Ahmed, Yaman B., Alqbelat, Jenan
Publikováno v:
In Biomedicine & Pharmacotherapy August 2023 164
Autor:
Elsalem, Lina M.I.
The aldehyde dehydrogenase (ALDH) superfamily is gaining momentum in regard to stem cell and cancer research. However, their regulation and expression in the cancer microenvironment is poorly understood. The aim of this work was to understand the rol
Externí odkaz:
http://hdl.handle.net/10454/11800
Serum Leptin Receptor and the rs1137101 Variant of the LEPR Gene Are Associated with Bladder Cancer.
Autor:
Alfaqih, Mahmoud A.1,2 (AUTHOR) mahmoudmaf@agu.edu.bh, Elsalem, Lina3 (AUTHOR) lmelsalem@just.edu.jo, Nusier, Mohamad2 (AUTHOR) kralmhidat10@sci.just.edu.jo, Mhedat, Khawla2 (AUTHOR) eyababneh@just.edu.jo, Khader, Yousef4 (AUTHOR) yskhader@just.edu.jo, Ababneh, Ebaa2 (AUTHOR)
Publikováno v:
Biomolecules (2218-273X). Oct2023, Vol. 13 Issue 10, p1498. 12p.
The aldehyde dehydrogenase (ALDH) superfamily is gaining momentum in regard to stem cell and cancer research. However, their regulation and expression in the cancer microenvironment is poorly understood. The aim of this work was to understand the rol
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.707684
Autor:
Al-Nabulsi, Anas A., Jaradat, Ziad W., Al Qudsi, Farah R., Elsalem, Lina, Osaili, Tareq M., Olaimat, Amin N., Esposito, Gennaro, Liu, Shao-Quan, Ayyash, Mutamed M.
Publikováno v:
In LWT 15 September 2022 167
Publikováno v:
In Annals of Medicine and Surgery February 2021 62:326-333
Publikováno v:
In Annals of Medicine and Surgery January 2021 61:126-131
Publikováno v:
In Heliyon December 2020 6(12)