Design, synthesis, and biological evaluation of new pyrazoloquinazoline derivatives as dual COX-2/5-LOX inhibitors.

Autor: Shaaban MA; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt., Kamal AM; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.; Department of Organic Chemistry, Faculty of Pharmacy, October University for Modern Science and Arts (MSA), Giza, Egypt., Faggal SI; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt., Farag NA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Misr International University, Cairo, Egypt., Aborehab NM; Department of Biochemistry, Faculty of Pharmacy, October University for Modern Science and Arts (MSA), Giza, Egypt., Elsahar AE; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, Egypt., Mohamed KO; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.

Publikováno v: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2020 Nov; Vol. 353 (11), pp. e2000027. Date of Electronic Publication: 2020 Jul 21.