Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Elsa Zacco"'
Autor:
Eleonora Perego, Sabrina Zappone, Francesco Castagnetti, Davide Mariani, Erika Vitiello, Jakob Rupert, Elsa Zacco, Gian Gaetano Tartaglia, Irene Bozzoni, Eli Slenders, Giuseppe Vicidomini
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Biomolecular condensates serve as membrane-less compartments within cells, concentrating proteins and nucleic acids to facilitate precise spatial and temporal orchestration of various biological processes. The diversity of these processes an
Externí odkaz:
https://doaj.org/article/7529e259296b4e6d894425d6ea688614
Autor:
Giacomo Parisi, Roberta Piacentini, Alessio Incocciati, Alessandra Bonamore, Alberto Macone, Jakob Rupert, Elsa Zacco, Mattia Miotto, Edoardo Milanetti, Gian Gaetano Tartaglia, Giancarlo Ruocco, Alberto Boffi, Lorenzo Di Rienzo
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2024)
The development of methods able to modulate the binding affinity between proteins and peptides is of paramount biotechnological interest in view of a vast range of applications that imply designed polypeptides capable to impair or favour Protein-Prot
Externí odkaz:
https://doaj.org/article/7a5d138e1b4c4cc189f2c031fc731c96
Autor:
Roberto Giambruno, Elsa Zacco, Camilla Ugolini, Andrea Vandelli, Logan Mulroney, Manfredi D’Onghia, Bianca Giuliani, Elena Criscuolo, Matteo Castelli, Nicola Clementi, Massimo Clementi, Nicasio Mancini, Tiziana Bonaldi, Stefano Gustincich, Tommaso Leonardi, Gian Gaetano Tartaglia, Francesco Nicassio
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102052- (2023)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a positive single-stranded RNA virus, engages in complex interactions with host cell proteins throughout its life cycle. While these interactions enable the host to recognize and inhibit v
Externí odkaz:
https://doaj.org/article/6eb7df49e017486c8f0fe36a0099dc99
Autor:
Elsa Zacco, Owen Kantelberg, Edoardo Milanetti, Alexandros Armaos, Francesco Paolo Panei, Jenna Gregory, Kiani Jeacock, David J. Clarke, Siddharthan Chandran, Giancarlo Ruocco, Stefano Gustincich, Mathew H. Horrocks, Annalisa Pastore, Gian Gaetano Tartaglia
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Here, the authors generated an artificial RNA molecule, or aptamer, specific for the Amyotrophic Lateral Sclerosis protein TDP-43. By interacting avidly with its target, the aptamer can be exploited to track TDP-43 phase transition in vitro and in ce
Externí odkaz:
https://doaj.org/article/313504fc94a146ba963e22a3b9d3a822
Autor:
Paola Valentini, Bianca Pierattini, Elsa Zacco, Damiano Mangoni, Stefano Espinoza, Natalie A. Webster, Byron Andrews, Piero Carninci, Gian Gaetano Tartaglia, Luca Pandolfini, Stefano Gustincich
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 1092-1102 (2022)
SINEUPs are a novel class of natural and synthetic non-coding antisense RNA molecules able to increase the translation of a target mRNA. They present a modular organization comprising an unstructured antisense target-specific domain, which sets the s
Externí odkaz:
https://doaj.org/article/a464e6b7573848c49f5c81e1322c029f
Autor:
Giulia Milordini, Elsa Zacco, Matthew Percival, Rita Puglisi, Fabrizio Dal Piaz, Pierandrea Temussi, Annalisa Pastore
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Epidemiological evidence shows an increased risk for developing Alzheimer’s disease in people affected by diabetes, a pathology associated with increased hyperglycemia. A potential factor that could explain this link could be the role that sugars m
Externí odkaz:
https://doaj.org/article/dbb8bf2807dc4df296c157a1221b80b8
Autor:
Greta Grassmann, Mattia Miotto, Lorenzo Di Rienzo, Federico Salaris, Beatrice Silvestri, Elsa Zacco, Alessandro Rosa, Gian Gaetano Tartaglia, Giancarlo Ruocco, Edoardo Milanetti
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1905 (2021)
Many of the molecular mechanisms underlying the pathological aggregation of proteins observed in neurodegenerative diseases are still not fully understood. Among the aggregate-associated diseases, Amyotrophic Lateral Sclerosis (ALS) is of relevant im
Externí odkaz:
https://doaj.org/article/d2767e5b90004e139239c213c04cd631
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 11, Pp 2215-2216 (2021)
Externí odkaz:
https://doaj.org/article/c8acd4efbee849ebbd4b5247c493092d
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
The TAR DNA-binding protein 43 (TDP-43) is a nucleic acid-binding protein implicated in gene regulation and RNA processing and shuffling. It is a ribonuclear protein that carries out most of its functions by binding specific nucleic acid sequences wi
Externí odkaz:
https://doaj.org/article/1a610858909f416d8095d89d633f3ce4
Autor:
Esther Llop, Ana Ardá, Elsa Zacco, Roisin O’Flaherty, María-Salud García-Ayllón, Massimo Aureli, Moran Frenkel-Pinter, Celso A. Reis, Ole K. Greiner-Tollersrud, Inmaculada Cuchillo-Ibáñez
Publikováno v:
Glycoconjugate Journal. 39:579-586
The Cost Action “Innovation with glycans: new frontiers from synthesis to new biological targets” (INNOGLY) hosted the Workshop “Neuroglycoproteins in health and disease”, in Alicante, Spain, on March 2022. This event brought together an euro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::724405a1b40679ce18db4b6cf1987877
https://doi.org/10.1007/s10719-022-10078-4
https://doi.org/10.1007/s10719-022-10078-4