Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Elsa Hernando"'
Autor:
Elsa Hernando, Valeria Capurro, Claudia Cossu, Michele Fiore, María García-Valverde, Vanessa Soto-Cerrato, Ricardo Pérez-Tomás, Oscar Moran, Olga Zegarra-Moran, Roberto Quesada
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Anion selective ionophores, anionophores, are small molecules capable of facilitating the transmembrane transport of anions. Inspired in the structure of natural product prodigiosin, four novel anionophores 1a-d, including a 1,2,3-triazole g
Externí odkaz:
https://doaj.org/article/fc47a172d0f34f89a359a289471393b9
Autor:
Ricardo Pérez-Tomás, Vanessa Soto-Cerrato, Roberto Quesada, Juan Moya, Margarida Fardilha, Ricard Ramos, Ananda M. Rodilla, David Martínez-García, Alberto Villanueva, Elsa Hernando, Luís Korrodi-Gregório, Pilar Manuel-Manresa
QIAGEN Cancer Drug Targets Array file containing the raw data (Ct information) for the qPCR of all the conditions (both A549 and SW900 cell lines).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c06cd0f1208d4cfbc3c64975b4d8318
https://doi.org/10.1158/1535-7163.22503079.v1
https://doi.org/10.1158/1535-7163.22503079.v1
Autor:
Ricardo Pérez-Tomás, Vanessa Soto-Cerrato, Roberto Quesada, Juan Moya, Margarida Fardilha, Ricard Ramos, Ananda M. Rodilla, David Martínez-García, Alberto Villanueva, Elsa Hernando, Luís Korrodi-Gregório, Pilar Manuel-Manresa
Supplementary Figures: Figure S1. Set of tambjamine analogues investigated; Figure S2. General reaction scheme; Figure S3. 1H NMR (DMSO-d6) of compound 3.HCl; Figure S4. 13C (DMSO-d6) of compound 3.HCl; Figure S5. HRMS (EI) of compound 3; Figure S6.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::036bd4924ebaac44e86048ffd32452c2
https://doi.org/10.1158/1535-7163.22503082
https://doi.org/10.1158/1535-7163.22503082
Autor:
Elsa Hernando, Saúl Vallejos, Félix C. García, Roberto Quesada, María García-Valverde, María Jesús Cabero, Miriam Trigo, José M. García, David Iturbe
Publikováno v:
Repositorio Institucional de la Universidad de Burgos (RIUBU)
instname
instname
We have developed a new extremely hydrophilic polymeric film suitable for the detection and quantification of chloride in human sweat directly on the skin. The film, or membrane, has chemically anchored 6-methoxyquinoline groups as chloride responsiv
Autor:
Ananda M. Rodilla, Alberto Villanueva, Margarida Fardilha, Pilar Manuel-Manresa, J. Moya, Elsa Hernando, Roberto Quesada, Luís Korrodi-Gregório, David Martínez-García, Ricard Ramos, Vanessa Soto-Cerrato, Ricardo Pérez-Tomás
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Repositorio Institucional de la Universidad de Burgos (RIUBU)
instname
Universidad de Barcelona
Repositorio Institucional de la Universidad de Burgos (RIUBU)
instname
Lung cancer has become the leading killer cancer worldwide, due to late diagnosis and lack of efficient anticancer drugs. We have recently described novel natural-derived tambjamine analogues that are potent anion transporters capable of disrupting c
Autor:
Eloisa Jantus-Lewintre, Víctor Fernández-Dueñas, Ricardo Pérez-Tomás, Pilar Manuel-Manresa, Roberto Quesada, Ananda M. Rodilla, Rosa Farràs, Silvia Calabuig-Fariñas, Alicia Martínez-Romero, Elsa Hernando, Kristoffer Sahlholm, María García-Valverde, Thomas Knöpfel, Francisco Ciruela, Vanessa Soto-Cerrato
Publikováno v:
Repositorio Institucional de la Universidad de Burgos (RIUBU)
instname
Dipòsit Digital de la UB
Universidad de Barcelona
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)
instname
Dipòsit Digital de la UB
Universidad de Barcelona
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)
Facilitated anion transport potentially represents a powerful tool to modulate various cellular functions. However, research into the biological effects of small molecule anionophores is still at an early stage. Here we have used two potent anionopho
Autor:
Roberto Quesada, Vanessa Soto-Cerrato, María García-Valverde, Oscar Moran, Valeria Capurro, Claudia Cossu, Olga Zegarra-Moran, Elsa Hernando, Michele Fiore, Ricardo Pérez-Tomás
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Repositorio Institucional de la Universidad de Burgos (RIUBU)
instname
Recercat. Dipósit de la Recerca de Catalunya
Scientific reports (Nature Publishing Group) 8 (2018). doi:10.1038/s41598-018-20708-3
info:cnr-pdr/source/autori:Hernando E, Capurro V, Cossu C, Fiore M, García-Valverde M, Soto-Cerrato V, Pérez-Tomás R, Moran O, Zegarra-Moran O, Quesada R/titolo:Small molecule anionophores promote transmembrane anion permeation matching CFTR activity/doi:10.1038%2Fs41598-018-20708-3/rivista:Scientific reports (Nature Publishing Group)/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:8
Dipòsit Digital de la UB
Universidad de Barcelona
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Repositorio Institucional de la Universidad de Burgos (RIUBU)
instname
Recercat. Dipósit de la Recerca de Catalunya
Scientific reports (Nature Publishing Group) 8 (2018). doi:10.1038/s41598-018-20708-3
info:cnr-pdr/source/autori:Hernando E, Capurro V, Cossu C, Fiore M, García-Valverde M, Soto-Cerrato V, Pérez-Tomás R, Moran O, Zegarra-Moran O, Quesada R/titolo:Small molecule anionophores promote transmembrane anion permeation matching CFTR activity/doi:10.1038%2Fs41598-018-20708-3/rivista:Scientific reports (Nature Publishing Group)/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:8
Dipòsit Digital de la UB
Universidad de Barcelona
Anion selective ionophores, anionophores, are small molecules capable of facilitating the transmembrane transport of anions. Inspired in the structure of natural product prodigiosin, four novel anionophores 1a-d, including a 1,2,3-triazole group, wer
Autor:
Victor Guallar, Pilar Manuel-Manresa, Roberto Quesada, Modesto Orozco, Ricardo Pérez-Tomás, Vanessa Soto-Cerrato, Elsa Hernando, Martin Kotev
Publikováno v:
Repositorio Institucional de la Universidad de Burgos (RIUBU)
instname
Dipòsit Digital de la UB
Universidad de Barcelona
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Combining computational modeling, de novo compound synthesis, and in vitro and cellular assays, we have performed an inhibition study against the enhancer of zeste homolog 2 (EZH2) histone-lysine N-methyltransferase. This enzyme is an important catal
Autor:
Elsa Hernando Santa Cruz
Publikováno v:
Repositorio Institucional de la Universidad de Burgos (RIUBU)
instname
instname
En la presente tesis se han sintetizado moléculas sencillas con capacidad para realizar la función que en la naturaleza realizan proteínas de membrana, esto es facilitar el transporte de aniones a través de membranas lipídicas, lo cual es un obj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fabafecaeaa004cfb8487c5ec49b95b
http://hdl.handle.net/10259/5889
http://hdl.handle.net/10259/5889
Autor:
Pilar Manuel-Manresa, Roberto Quesada, Ananda M. Rodilla, Luís Korrodi-Gregório, Ricardo Pérez-Tomás, Elsa Hernando, Vanessa Soto-Cerrato
Publikováno v:
Repositorio Institucional de la Universidad de Burgos (RIUBU)
instname
Recercat. Dipósit de la Recerca de Catalunya
Dipòsit Digital de la UB
Universidad de Barcelona
instname
Recercat. Dipósit de la Recerca de Catalunya
Dipòsit Digital de la UB
Universidad de Barcelona
Current pharmacological treatments for lung cancer show very poor clinical outcomes, therefore, the development of novel anticancer agents with innovative mechanisms of action is urgently needed. Cancer cells have a reversed pH gradient compared to n