Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Elsa C. Chan"'
Autor:
Asitha Balachandra, Elsa C. Chan, Joseph P. Paul, Sze Ng, Vicki Chrysostomou, Steven Ngo, Roshan Mayadunne, Peter van Wijngaarden
Publikováno v:
Drug Delivery, Vol 26, Iss 1, Pp 343-353 (2019)
Age-related macular degeneration (AMD) is a leading cause of vision loss, the treatment of which may require monthly intravitreal injections. This is a burden on patients and health services, and new delivery modalities that reduce injection frequenc
Externí odkaz:
https://doaj.org/article/71cad5ee3a36494ea07eaf442c9b38ff
Publikováno v:
Antioxidants, Vol 10, Iss 2, p 238 (2021)
Glaucoma is characterised by loss of retinal ganglion cells, and their axons and many pathophysiological processes are postulated to be involved. It is increasingly understood that not one pathway underlies glaucoma aetiology, but rather they occur a
Externí odkaz:
https://doaj.org/article/09b5455f43a04b93b26105ee6a743dba
Autor:
Manisha H. Shah, Elsa C. Chan, Nicole J. Van Bergen, Surinder S. Pandav, Sze Ng, Jonathan G. Crowston, Hitesh M. Peshavariya
Publikováno v:
Antioxidants, Vol 9, Iss 11, p 1126 (2020)
Collagen accumulation in sub-conjunctival tissue at the surgical wound is one of the major complications associated with glaucoma filtration surgery (GFS). This process often leads to unwanted fibrotic scar formation at the lesion site and dysfunctio
Externí odkaz:
https://doaj.org/article/26ff7808c89d4a67b4c2c06473943387
Publikováno v:
Redox Biology, Vol 2, Iss C, Pp 267-272 (2014)
Uncontrolled fibrosis in organs like heart, kidney, liver and lung is detrimental and may lead to end-stage organ failure. Currently there is no effective treatment for fibrotic disorders. Transforming growth factor (TGF)-β has a fundamental role in
Externí odkaz:
https://doaj.org/article/9506890eb9e2436ab81f259dc8c2b1cc
Publikováno v:
Cells, Vol 1, Iss 4, Pp 976-993 (2012)
In this review, we summarize advances in our understanding of redox-sensitive mechanisms that regulate adipogenesis. Current evidence indicates that reactive oxygen species may act to promote both the initiation of adipocyte lineage commitment of pre
Externí odkaz:
https://doaj.org/article/30fe0d9e2bcd49ac9e07b2c72186e9cf
Autor:
Selwyn M. Prea, Elsa C. Chan, Gregory J. Dusting, Algis J. Vingrys, Bang V. Bui, Guei-Sheung Liu
Publikováno v:
Journal of Ophthalmology, Vol 2015 (2015)
Age-related macular degeneration (AMD) is the leading cause of substantial and irreversible vision loss amongst elderly populations in industrialized countries. The advanced neovascular (or “wet”) form of the disease is responsible for severe and
Externí odkaz:
https://doaj.org/article/a1ed86332f234383bd82ad6b5fa6276a
Autor:
Han-En Tsai, Jian-Ching Wu, Mei-Lang Kung, Li-Feng Liu, Lai-Hsin Kuo, Hsiao-Mei Kuo, San-Cher Chen, Elsa C. Chan, Chieh-Shan Wu, Ming-Hong Tai, Guei-Sheung Liu
Publikováno v:
PLoS ONE, Vol 8, Iss 6 (2013)
Externí odkaz:
https://doaj.org/article/d80593705c2f404f994fe139487a23c4
Autor:
Jennifer C, Fan Gaskin, Roy C K, Kong, Manisha H, Shah, Amanda J, Edgley, Hitesh M, Peshavariya, Elsa C, Chan
Publikováno v:
Translational Vision Science & Technology. 11:18
Cytotoxic agents such as mitomycin C (MMC) are part of the mainstay treatment for limiting subconjunctival scarring following glaucoma filtration surgery (GFS). However, a safer antifibrotic therapy is clinically needed. The anti-scarring properties
Autor:
Elsa C. Chan, Joseph Paul, Sze Ng, Roshan T. A. Mayadunne, Steven Ngo, Asitha Indaka Balachandra, Peter van Wijngaarden, Vicki Chrysostomou
Publikováno v:
Drug Delivery, Vol 26, Iss 1, Pp 343-353 (2019)
Drug Delivery
Drug Delivery
Age-related macular degeneration (AMD) is a leading cause of vision loss, the treatment of which may require monthly intravitreal injections. This is a burden on patients and health services, and new delivery modalities that reduce injection frequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a5b4173496d990157d8e3eb224e12f
Publikováno v:
The American Journal of Pathology. 188:838-845
Transplant vasculopathy is one of the major causes of chronic rejection after solid organ transplantation. The pathogenic mechanisms of transplant vasculopathy are still poorly understood. Herein, we summarize current evidence suggesting that activat