Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Elsa C Chan"'
Autor:
Elsa C Chan, Shyh-Ming Kuo, Anne M Kong, Wayne A Morrison, Gregory J Dusting, Geraldine M Mitchell, Shiang Y Lim, Guei-Sheung Liu
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149799 (2016)
Here, we describe a porous 3-dimensional collagen scaffold material that supports capillary formation in vitro, and promotes vascularization when implanted in vivo. Collagen scaffolds were synthesized from type I bovine collagen and have a uniform po
Externí odkaz:
https://doaj.org/article/a1722d3c9f8b4dffb0d1f740eed7a5c0
Autor:
Han-En Tsai, Jian-Ching Wu, Mei-Lang Kung, Li-Feng Liu, Lai-Hsin Kuo, Hsiao-Mei Kuo, San-Cher Chen, Elsa C Chan, Chieh-Shan Wu, Ming-Hong Tai, Guei-Sheung Liu
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59345 (2013)
Cutaneous malignant melanoma is the fastest increasing malignancy in humans. Hepatoma-derived growth factor (HDGF) is a novel growth factor identified from human hepatoma cell line. HDGF overexpression is correlated with poor prognosis in various typ
Externí odkaz:
https://doaj.org/article/07456c78a88b4cd1ae7842ccf0b5476b
Autor:
Hitesh M Peshavariya, Caroline J Taylor, Celeste Goh, Guei-Sheung Liu, Fan Jiang, Elsa C Chan, Gregory J Dusting
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60790 (2013)
The anti-inflammatory peptide annexin-1 binds to formyl peptide receptors (FPR) but little is known about its mechanism of action in the vasculature. Here we investigate the effect of annexin peptide Ac2-26 on NADPH oxidase activity induced by tumour
Externí odkaz:
https://doaj.org/article/b005069908414f9c9079d65e23a56208
Publikováno v:
Redox Biology, Vol 2, Iss C, Pp 267-272 (2014)
Uncontrolled fibrosis in organs like heart, kidney, liver and lung is detrimental and may lead to end-stage organ failure. Currently there is no effective treatment for fibrotic disorders. Transforming growth factor (TGF)-β has a fundamental role in
Externí odkaz:
https://doaj.org/article/9506890eb9e2436ab81f259dc8c2b1cc
Autor:
Jennifer C, Fan Gaskin, Roy C K, Kong, Manisha H, Shah, Amanda J, Edgley, Hitesh M, Peshavariya, Elsa C, Chan
Publikováno v:
Translational Vision Science & Technology. 11:18
Cytotoxic agents such as mitomycin C (MMC) are part of the mainstay treatment for limiting subconjunctival scarring following glaucoma filtration surgery (GFS). However, a safer antifibrotic therapy is clinically needed. The anti-scarring properties
Autor:
Elsa C. Chan, Joseph Paul, Sze Ng, Roshan T. A. Mayadunne, Steven Ngo, Asitha Indaka Balachandra, Peter van Wijngaarden, Vicki Chrysostomou
Publikováno v:
Drug Delivery, Vol 26, Iss 1, Pp 343-353 (2019)
Drug Delivery
Drug Delivery
Age-related macular degeneration (AMD) is a leading cause of vision loss, the treatment of which may require monthly intravitreal injections. This is a burden on patients and health services, and new delivery modalities that reduce injection frequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a5b4173496d990157d8e3eb224e12f
Publikováno v:
The American Journal of Pathology. 188:838-845
Transplant vasculopathy is one of the major causes of chronic rejection after solid organ transplantation. The pathogenic mechanisms of transplant vasculopathy are still poorly understood. Herein, we summarize current evidence suggesting that activat
Publikováno v:
Antioxidants, Vol 10, Iss 238, p 238 (2021)
Antioxidants
Antioxidants
Glaucoma is characterised by loss of retinal ganglion cells, and their axons and many pathophysiological processes are postulated to be involved. It is increasingly understood that not one pathway underlies glaucoma aetiology, but rather they occur a
Autor:
Elsa C. Chan, Gregory J. Dusting, Jian-Ching Wu, Han-En Tsai, Ming-Hong Tai, Chieh-Shan Wu, Guei-Sheung Liu
Publikováno v:
Free Radical Biology and Medicine. 162:175
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Corneal injury that occurs after burning with alkali initiates wound-healing processes, including inflammation, neovascularization, and fibrosis. Excessive reactions to injury can reduce corneal transparency and thereby compromise vision. The