Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Elsa C Chan"'
Autor:
Asitha Balachandra, Elsa C. Chan, Joseph P. Paul, Sze Ng, Vicki Chrysostomou, Steven Ngo, Roshan Mayadunne, Peter van Wijngaarden
Publikováno v:
Drug Delivery, Vol 26, Iss 1, Pp 343-353 (2019)
Age-related macular degeneration (AMD) is a leading cause of vision loss, the treatment of which may require monthly intravitreal injections. This is a burden on patients and health services, and new delivery modalities that reduce injection frequenc
Externí odkaz:
https://doaj.org/article/71cad5ee3a36494ea07eaf442c9b38ff
Publikováno v:
Antioxidants, Vol 10, Iss 2, p 238 (2021)
Glaucoma is characterised by loss of retinal ganglion cells, and their axons and many pathophysiological processes are postulated to be involved. It is increasingly understood that not one pathway underlies glaucoma aetiology, but rather they occur a
Externí odkaz:
https://doaj.org/article/09b5455f43a04b93b26105ee6a743dba
Autor:
Manisha H. Shah, Elsa C. Chan, Nicole J. Van Bergen, Surinder S. Pandav, Sze Ng, Jonathan G. Crowston, Hitesh M. Peshavariya
Publikováno v:
Antioxidants, Vol 9, Iss 11, p 1126 (2020)
Collagen accumulation in sub-conjunctival tissue at the surgical wound is one of the major complications associated with glaucoma filtration surgery (GFS). This process often leads to unwanted fibrotic scar formation at the lesion site and dysfunctio
Externí odkaz:
https://doaj.org/article/26ff7808c89d4a67b4c2c06473943387
Publikováno v:
Redox Biology, Vol 2, Iss C, Pp 267-272 (2014)
Uncontrolled fibrosis in organs like heart, kidney, liver and lung is detrimental and may lead to end-stage organ failure. Currently there is no effective treatment for fibrotic disorders. Transforming growth factor (TGF)-β has a fundamental role in
Externí odkaz:
https://doaj.org/article/9506890eb9e2436ab81f259dc8c2b1cc
Autor:
Elsa C Chan, Shyh-Ming Kuo, Anne M Kong, Wayne A Morrison, Gregory J Dusting, Geraldine M Mitchell, Shiang Y Lim, Guei-Sheung Liu
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149799 (2016)
Here, we describe a porous 3-dimensional collagen scaffold material that supports capillary formation in vitro, and promotes vascularization when implanted in vivo. Collagen scaffolds were synthesized from type I bovine collagen and have a uniform po
Externí odkaz:
https://doaj.org/article/a1722d3c9f8b4dffb0d1f740eed7a5c0
Publikováno v:
Cells, Vol 1, Iss 4, Pp 976-993 (2012)
In this review, we summarize advances in our understanding of redox-sensitive mechanisms that regulate adipogenesis. Current evidence indicates that reactive oxygen species may act to promote both the initiation of adipocyte lineage commitment of pre
Externí odkaz:
https://doaj.org/article/30fe0d9e2bcd49ac9e07b2c72186e9cf
Autor:
Selwyn M. Prea, Elsa C. Chan, Gregory J. Dusting, Algis J. Vingrys, Bang V. Bui, Guei-Sheung Liu
Publikováno v:
Journal of Ophthalmology, Vol 2015 (2015)
Age-related macular degeneration (AMD) is the leading cause of substantial and irreversible vision loss amongst elderly populations in industrialized countries. The advanced neovascular (or “wet”) form of the disease is responsible for severe and
Externí odkaz:
https://doaj.org/article/a1ed86332f234383bd82ad6b5fa6276a
Autor:
Jennifer C, Fan Gaskin, Roy C K, Kong, Manisha H, Shah, Amanda J, Edgley, Hitesh M, Peshavariya, Elsa C, Chan
Publikováno v:
Translational Vision Science & Technology. 11:18
Cytotoxic agents such as mitomycin C (MMC) are part of the mainstay treatment for limiting subconjunctival scarring following glaucoma filtration surgery (GFS). However, a safer antifibrotic therapy is clinically needed. The anti-scarring properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b238c7cf40b48b03019ad96c55ac70f
https://doi.org/10.1167/tvst.11.8.18
https://doi.org/10.1167/tvst.11.8.18
Autor:
Han-En Tsai, Jian-Ching Wu, Mei-Lang Kung, Li-Feng Liu, Lai-Hsin Kuo, Hsiao-Mei Kuo, San-Cher Chen, Elsa C Chan, Chieh-Shan Wu, Ming-Hong Tai, Guei-Sheung Liu
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59345 (2013)
Cutaneous malignant melanoma is the fastest increasing malignancy in humans. Hepatoma-derived growth factor (HDGF) is a novel growth factor identified from human hepatoma cell line. HDGF overexpression is correlated with poor prognosis in various typ
Externí odkaz:
https://doaj.org/article/07456c78a88b4cd1ae7842ccf0b5476b
Autor:
Hitesh M Peshavariya, Caroline J Taylor, Celeste Goh, Guei-Sheung Liu, Fan Jiang, Elsa C Chan, Gregory J Dusting
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60790 (2013)
The anti-inflammatory peptide annexin-1 binds to formyl peptide receptors (FPR) but little is known about its mechanism of action in the vasculature. Here we investigate the effect of annexin peptide Ac2-26 on NADPH oxidase activity induced by tumour
Externí odkaz:
https://doaj.org/article/b005069908414f9c9079d65e23a56208