A Thyroid Genetic Classifier Correctly Predicts Benign Nodules with Indeterminate Cytology: Two Independent, Multicenter, Prospective Validation Trials

Autor: Milagros Bracamonte, Elsa Bruce, Marcela Lagos, Antonieta Solar, Félix Vasquez, Naifa L. Busaidy, Miren Osorio, Augusto León, Hernán Tala, René E Díaz, Luis Marín, Tatiana Arias, John Stewart, Emad Kandil, Giovanna Miranda, Jesús Véliz, Alice Tang, Dina Schachter, Eleonora Horvath, Jiang Wang, José Carlos de Miguel Domínguez, Marcela Henríquez, Carmen Franco, Juan Carlos Roa, Paul H. Graham, Mark Zafereo, Hernán E. González, Nicolás Droppelman, Christina S. Kong, Lisa A. Orloff, Maite Lobos, F. Christopher Holsinger, Natalia Mena, Bryan McIver, Patricia Arroyo, Pedro Pineda, Soledad Loyola, David L. Steward, Nelson Wohllk, Francisco Cruz, Michelle A. Williams, Elizabeth G. Grubbs, Eufrosina Traipe, Sergio Vargas-Salas, Francisco Medina

Publikováno v: Thyroid

Background: Although most thyroid nodules with indeterminate cytology are benign, in most of the world, surgery remains as the most frequent diagnostic approach. We have previously reported a 10-gene thyroid genetic classifier, which accurately predi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::689d7ca4e93171276fff7dd3eecadbb0
https://pubmed.ncbi.nlm.nih.gov/31910118

Oral administration of recombinant Neisseria meningitidis PorA genetically fused to H. pylori HpaA antigen increases antibody levels in mouse serum, suggesting that PorA behaves as a putative adjuvant

Autor: Daniel A. Soto, Elsa Bruce, Macarena Mosqueira, Aurora E Maldonado, Magaly J Barrientos, Ricardo A Manzo, Paul R. Harris, Jorge Touma, Anastasia Avila, Abel E. Vasquez, Alejandro Venegas

Publikováno v: Human Vaccines & Immunotherapeutics

The Neisseria meningitidis outer membrane protein PorA from a Chilean strain was purified as a recombinant protein. PorA mixed with AbISCO induced bactericidal antibodies against N. meningitidis in mice. When PorA was fused to the Helicobacter pylori

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa7b245b7256a0dff5e2da208b182b20
https://pubmed.ncbi.nlm.nih.gov/25750999

Cloning and comparison of ten gene sequences of a Chilean H. pylori strain with other H. pylori strains revealed higher variability for VacA and CagA virulence factors

Autor: Elsa Bruce, Angelica Medina-Selby, Ilse Müller, Patricio Martı́nez, Arturo Yudelevich, Patricio Opazo, Pablo Valenzuela, Alejandro Venegas, Jose Luis Palacios, Marta Mancilla

Publikováno v: BIOLOGICAL RESEARCH
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Biological Research v.35 n.1 2002
SciELO Chile
Biological Research, Volume: 35, Issue: 1, Pages: 67-84, Published: 2002
Biological Research, Vol 35, Iss 1, Pp 67-84 (2002)

We have cloned and sequenced ten Helicobacter pylori genes from a Chilean strain (CH-CTX1) including: a cytotoxin VacA fragment, a CagA fragment (A17), a species-specific protein (TsaA), urease subunits (UreA, UreB), a flagellin subunit (FlaB), heat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd70bf3fdd513c34386ed3040bd7943e
https://pubmed.ncbi.nlm.nih.gov/12125208