Inherited variants affecting RNA editing may contribute to ovarian cancer susceptibility: results from a large-scale collaboration

Autor: John McLaughlin, Hanna Yang, Francesmary Modugno, Jennifer B. Permuth, Diana Eccles, Agnieszka Dansonka-Mieszkowska, Matthias W. Beckmann, Elizabeth M. Poole, Pamela J. Thompson, Maria Bisogna, Ellen L. Goode, Michelle A.T. Hildebrandt, Paul D.P. Pharoah, Zhihua Chen, Lambertus A. Kiemeney, Madalene Earp, Claus Høgdall, Jin Q. Cheng, Xifeng Wu, Aleksandra Gentry-Maharaj, Jenny Chang-Claude, Stacey J. Winham, Jan Lubinski, Andrew Berchuck, Valerie McGuire, Els Van Niewenhuyse, Arto Leminen, Ralf Bützow, Susan J. Ramus, Angela Brooks-Wilson, Joseph H. Rothstein, Argyrios Ziogas, Ignace Vergote, Ian G. Campbell, Steven A. Narod, Daniel W. Cramer, Simon A. Gayther, Diether Lambrechts, Heli Nevanlinna, Harvey A. Risch, Alice S. Whittemore, Lene Lundvall, Jolanta Lissowska, Kunle Odunsi, Kathryn L. Terry, Y. Ann Chen, Jacek Gronwald, Leon F.A.G. Massuger, Alvaro N.A. Monteiro, Louise A. Brinton, Marc T. Goodman, Celeste Leigh Pearce, Roberta B. Ness, Peter A. Fasching, Joseph L. Kelley, Linda E. Kelemen, Yurii B. Shvetsov, Elisa V. Bandera, Susanne K. Kjaer, Joellen M. Schildkraut, Graham G. Giles, Georgia Chenevix-Trench, Irene Orlow, Weiva Sieh, Liisa M. Pelttari, Catherine M. Phelan, Melissa Moffitt, Brett M. Reid, Jenny Lester, Adriaan Vanderstichele, Linda S. Cook, Usha Menon, Dong Liang, Brooke L. Fridley, Mary Anne Rossing, Julie M. Cunningham, Thilo Dörk, Douglas A. Levine, Shelley S. Tworoger, Allan Jensen, Thomas A. Sellers, Hoda Anton-Culver, Nhu D. Le, Honglin Song, Anna H. Wu, Kirsten B. Moysich, Line Bjørge, Sara H. Olson, Lynne R. Wilkens, Iain A. McNeish, Tanja Pejovic, Florian Heitz, Beth Y. Karlan, Natalia Bogdanova, Jennifer A. Doherty, Robert P. Edwards, Jolanta Kupryjanczyk, Nicolas Wentzensen, Karen H. Lu, Estrid Høgdall

Publikováno v: Oncotarget, 7, 45, pp. 72381-72394
Oncotarget, 7, 72381-72394
Oncotarget

RNA editing in mammals is a form of post-transcriptional modification in which adenosine is converted to inosine by the adenosine deaminases acting on RNA (ADAR) family of enzymes. Based on evidence of altered ADAR expression in epithelial ovarian ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec3722969270bcd1e3dcfe299f2752a
https://doi.org/10.18632/oncotarget.10546