Výsledky vyhledávání

Surface plasmon resonance imaging coupled to on-chip mass spectrometry: a new tool to probe protein-GAG interactions

Autor: Cédric Przybylski, Els Saesen, Régis Daniel, Hugues Lortat-Jacob, Florence Gonnet

Publikováno v: Analytical and Bioanalytical Chemistry
Analytical and Bioanalytical Chemistry, 2020, ⟨10.1007/s00216-019-02267-2⟩
Analytical and Bioanalytical Chemistry, Springer Verlag, 2020, ⟨10.1007/s00216-019-02267-2⟩

A biosensor device for the detection and characterization of protein-glycosaminoglycan interactions is being actively sought and constitutes the key to identifying specific carbohydrate ligands, an important issue in glycoscience. Mass spectrometry (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf381dd25fc2b7f7dd6fe43c86049ca
https://doi.org/10.1007/s00216-019-02267-2

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Discrimination of deletion to point cytokine mutants based on an array of cross-reactive receptors mimicking protein recognition by heparan sulfate

Autor: David Bonnaffé, Yulia N Sergeeva, Hugues Lortat-Jacob, Evelyne Gout, Maria Genua, Martial Billon, Els Saesen, Arnaud Buhot, Laurie-Amandine Garçon, Christine Le Narvor, Rabia Sadir, Thierry Livache, Benjamin Musnier, Yanxia Hou

Publikováno v: Analytical and Bioanalytical Chemistry
Analytical and Bioanalytical Chemistry, Springer Verlag, In press, ⟨10.1007/s00216-021-03516-z⟩
Analytical and Bioanalytical Chemistry, Springer Verlag, 2021, ⟨10.1007/s00216-021-03516-z⟩
Analytical and Bioanalytical Chemistry, 2022, 414, pp.551-559. ⟨10.1007/s00216-021-03516-z⟩

International audience; Differential sensing of proteins based on cross-reactive arrays and pattern recognition is a promising technique for the detection and identification of proteins. In this study, a rational biomimetic strategy has been used to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e01ba3777d95ec6e75da3c1c40aa8e45
https://hal.archives-ouvertes.fr/hal-03340313/document

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On-line capillary isoelectric focusing hyphenated to native electrospray ionization mass spectrometry for the characterization of interferon-γ and variants

Autor: Mehdi Prull-Janssen, Hugues Lortat-Jacob, Cédric Przybylski, Els Saesen, Anne Varenne, Meriem Mokaddem, Régis Daniel, Florence Gonnet

Publikováno v: Analyst
Analyst, Royal Society of Chemistry, 2015, 140 (2), pp.543-550. ⟨10.1039/c4an01305k⟩
Analyst, 2015, 140 (2), pp.543-550. ⟨10.1039/c4an01305k⟩

International audience; The on-line hyphenation of Capillary IsoElectric Focusing (CIEF) with ElectroSpray Ionization Mass Spectrometry (ESI/MS) has been carried out in a non-denaturing detection mode at the CIEF-MS interface. This CIEF-MS coupling m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4bb8af2aaf7df756930e09411bf3756
https://hal.archives-ouvertes.fr/hal-01096701

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Insights into the mechanism by which interferon-γ basic amino acid clusters mediate protein binding to heparan sulfate

Autor: Aline Thomas, Rabia Sadir, Els Saesen, Damien Maurin, Stéphane Sarrazin, Anne Imberty, Cédric Laguri, Hugues Lortat-Jacob

Publikováno v: Journal of the American Chemical Society
Journal of the American Chemical Society, American Chemical Society, 2013, 135 (25), pp.9384-90. ⟨10.1021/ja4000867⟩
Journal of the American Chemical Society, 2013, 135 (25), pp.9384-90. ⟨10.1021/ja4000867⟩
Journal of the American Chemical Society, American Chemical Society, 2013, pp.9384-9390

International audience; The extensive functional repertoire of heparin and heparan sulfate, which relies on their ability to interact with a large number of proteins, has recently emerged. To understand the forces that drive such interactions the bin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449e88cf77d9bcda731b948ebb242572
https://pubmed.ncbi.nlm.nih.gov/23734709

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Continuous evolution profiles for electronic-tongue-based analysis

Autor: Yanxia Hou, Dayane Tada Batista, Roberto Calemczuk, Jamal Koubachi, Maria Genua, David Bonnaffé, Thierry Livache, Hugues Lortat-Jacob, Cédric Laguri, Pauline Fornarelli, Els Saesen, Arnaud Buhot

Publikováno v: Angewandte Chemie International Edition
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2012, 51 (41), pp.10394-8. ⟨10.1002/anie.201205346⟩
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2012, 51 (41), pp.10394-10398. ⟨10.1002/anie.201205346⟩
Angewandte Chemie International Edition, 2012, 51 (41), pp.10394-10398. ⟨10.1002/anie.201205346⟩

Conventional biosensors and biochips rely on a “lock-andkey” recognition principle, for which specific ligands, such as aptamers, antibodies, or mimetics are needed. In contrast, electronic nose/tongue devices (eN/eT) use the differential binding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea148883a37cc0122e4712fc8497230
https://hal.archives-ouvertes.fr/hal-00871193

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