Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Els J. Klooster"'
Autor:
Annemarie Voorberg-van der Wel, Anne-Marie Zeeman, Sandra M van Amsterdam, Alexander van den Berg, Els J Klooster, Shiroh Iwanaga, Chris J Janse, Geert-Jan van Gemert, Robert Sauerwein, Niels Beenhakker, Gerrit Koopman, Alan W Thomas, Clemens H M Kocken
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54888 (2013)
A major challenge for strategies to combat the human malaria parasite Plasmodium vivax is the presence of hypnozoites in the liver. These dormant forms can cause renewed clinical disease after reactivation through unknown mechanisms. The closely rela
Externí odkaz:
https://doaj.org/article/f1865318bbbf4b1086ea7ef35ce6a2d2
Autor:
Lars C Vermaat, Nicole van der Werff, Ivonne G. Nieuwenhuis, Annemarie Voorberg-van der Wel, Anne-Marie Zeeman, Clemens H. M. Kocken, Onny Klop, Els J. Klooster
Publikováno v:
Analytical Chemistry
Efforts to eradicate Plasmodium vivax malaria are hampered by the presence of hypnozoites, persisting stages in the liver that can reactivate after prolonged periods of time enabling further transmission and causing renewed disease. Large-scale drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f106f42c01a250f8850a814278cf8dc
https://pubmed.ncbi.nlm.nih.gov/32267675
https://pubmed.ncbi.nlm.nih.gov/32267675
Autor:
Els J. Klooster, Oliver Simon, Thierry T. Diagana, Suresh B. Lakshminarayana, Bryan K. S. Yeung, Anne-Marie Zeeman, Christophe Bodenreider, Robert W. Sauerwein, Ravinder Reddy Kondreddi, Nicole van der Werff, Annemarie Voorberg-van der Wel, Clemens H. M. Kocken
Publikováno v:
Antimicrobial Agents and Chemotherapy, 60, 2858-63
Antimicrobial Agents and Chemotherapy, 60, 5, pp. 2858-63
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, 60, 5, pp. 2858-63
Antimicrobial Agents and Chemotherapy
Two Plasmodium PI4 kinase (PI4K) inhibitors, KDU691 and LMV599, were selected for in vivo testing as causal prophylactic and radical-cure agents for Plasmodium cynomolgi sporozoite-infected rhesus macaques, based on their in vitro activity against li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da49d49b4ab2d12cc4ee915c8120a035
https://doi.org/10.1128/aac.03080-15
https://doi.org/10.1128/aac.03080-15
Autor:
Thierry T. Diagana, Florian Nigsch, Tewis Bouwmeester, Els J. Klooster, Binesh Shrestha, Guglielmo Roma, Erika L. Flannery, Sven Schuierer, Anne-Marie Zeeman, Jetsumon Sattabongkot, Vorada Chuenchob, Niwat Kangwanrangsan, Annemarie Voorberg-van der Wel, Walter Carbone, Devendra Kumar Gupta, Nicole L Bertschi, Ivonne G. Nieuwenhuis, Bart W. Faber, Martin Beibel, Clemens H. M. Kocken, Nicole van der Werff, Sebastian A. Mikolajczak, Judith Knehr, Sam O. Hofman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43497f241e189e0f046e41d97c2dac8f
https://doi.org/10.7554/elife.41081.025
https://doi.org/10.7554/elife.41081.025
Autor:
Florian Nigsch, Thierry T. Diagana, Els J. Klooster, Devendra Kumar Gupta, Tewis Bouwmeester, Bart W. Faber, Guglielmo Roma, Binesh Shrestha, Anne-Marie Zeeman, Niwat Kangwanrangsan, Vorada Chuenchob, Judith Knehr, Sven Schuierer, Sebastian A. Mikolajczak, Erika L. Flannery, Nicole L Bertschi, Walter Carbone, Ivonne G. Nieuwenhuis, Jetsumon Sattabongkot, Sam O. Hofman, Martin Beibel, Nicole van der Werff, Annemarie Voorberg-van der Wel, Clemens H. M. Kocken
Publikováno v:
eLife, Vol 7 (2018)
Relapses of Plasmodium dormant liver hypnozoites compromise malaria eradication efforts. New radical cure drugs are urgently needed, yet the vast gap in knowledge of hypnozoite biology impedes drug discovery. We previously unraveled the transcriptome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f76ef075ad806bd83864fccde564a40
https://elifesciences.org/articles/41081
https://elifesciences.org/articles/41081
Autor:
Els J. Klooster, Robert W. Sauerwein, David Plouffe, Kelli L. Kuhen, Anne-Marie Zeeman, Geert-Jan van Gemert, Alan W. Thomas, Rachel Borboa, Clemens H. M. Kocken, Elizabeth A. Winzeler, Brice Campo, Kerstin Gagaring, Richard Glynne, Edmond J. Remarque, Sandra M. van Amsterdam, Adrian J. F. Luty, Annemarie Voorberg-van der Wel, Advait Nagle, Bryan K. S. Yeung, Zhong Chen, Jason Roland, Case W. McNamara, Thierry T. Diagana, Alexander van den Berg, Arnab K. Chatterjee, Didier Leroy
Publikováno v:
Antimicrobial Agents and Chemotherapy, 58, 1586-95
Antimicrobial Agents and Chemotherapy; Vol 58
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, 58, 3, pp. 1586-95
Antimicrobial agents and chemotherapy, vol 58, iss 3
Antimicrobial Agents and Chemotherapy; Vol 58
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, 58, 3, pp. 1586-95
Antimicrobial agents and chemotherapy, vol 58, iss 3
Preventing relapses of Plasmodium vivax malaria through a radical cure depends on use of the 8-aminoquinoline primaquine, which is associated with safety and compliance issues. For future malaria eradication strategies, new, safer radical curative co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4e4c0443476d14226de728c1d2b8ab4
http://hdl.handle.net/2066/138513
http://hdl.handle.net/2066/138513