Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Els Hermans"'
Autor:
Enrico Radaelli, Els Hermans, Lorna Omodho, Annick Francis, Sara Vander Borght, Jean-Christophe Marine, Joost van den Oord, Frédéric Amant
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0124974 (2015)
Patient-derived tumor xenograft (PDTX) approach is nowadays considered a reliable preclinical model to study in vivo cancer biology and therapeutic response. NOD scid and Il2rg-deficient mice represent the "gold standard" host for the generation of P
Externí odkaz:
https://doaj.org/article/b25ad4c198764e30a714a0e1b857842d
Spontaneous early-onset neurodegeneration in the brainstem and spinal cord of NSG, NOG, and NXG mice
Autor:
Giovanni Finesso, Elinor Willis, James Carmine Tarrant, Matthew Lanza, Justin Sprengers, Jillian Verrelle, Esha Banerjee, Els Hermans, Charles-Antoine Assenmacher, Enrico Radaelli
Publikováno v:
Veterinary Pathology. 60:374-383
The spectrum of background, incidental, and experimentally induced lesions affecting NSG and NOG mice has been the subject of intense investigation. However, comprehensive studies focusing on the spontaneous neuropathological changes of these immunoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2af03a6f75b7074f3576cdee24f49a59
https://doi.org/10.1177/03009858231151403
https://doi.org/10.1177/03009858231151403
Autor:
Frédéric Amant, Tjalling Bosse, Philippe Moerman, Els Hermans, Ellen Gommé, Debby Thomas, Godelieve Verbist, Miriam Mints, Eva Wardelmann, Michael R. Mallmann, Leonardus F. Massuger, Ronald P. Zweemer, Carole Mestdagh, Maciej Stukan, Helga B. Salvesen, Farid Moinfar, Johannes Haybaeck, Olli Carpén, Jutta Huvila, Pavel Dundr, Michal Zikan, Mariël Brinkhuis, Roy P.M. Kruitwagen, Koen Van de Vijver, Angel Garcia-Jimenez, Eva Colas, Natalja ter Haar, Jone Trovik, An Coosemans, Daniela Annibali, Tine Cuppens
Supplementary methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46457c14e4483f936f1f05889c8a5b82
https://doi.org/10.1158/1078-0432.22466286
https://doi.org/10.1158/1078-0432.22466286
Autor:
Frédéric Amant, Tjalling Bosse, Philippe Moerman, Els Hermans, Ellen Gommé, Debby Thomas, Godelieve Verbist, Miriam Mints, Eva Wardelmann, Michael R. Mallmann, Leonardus F. Massuger, Ronald P. Zweemer, Carole Mestdagh, Maciej Stukan, Helga B. Salvesen, Farid Moinfar, Johannes Haybaeck, Olli Carpén, Jutta Huvila, Pavel Dundr, Michal Zikan, Mariël Brinkhuis, Roy P.M. Kruitwagen, Koen Van de Vijver, Angel Garcia-Jimenez, Eva Colas, Natalja ter Haar, Jone Trovik, An Coosemans, Daniela Annibali, Tine Cuppens
Combination of the mTORC1/2 inhibitor TAK-228 and the PI3K-α inhibitor alpelisib inhibits EMC041 tumor growth to the same extent as BEZ235
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f70365631ceb41f03592fce7015de85
https://doi.org/10.1158/1078-0432.22466289
https://doi.org/10.1158/1078-0432.22466289
Autor:
Frédéric Amant, Tjalling Bosse, Philippe Moerman, Els Hermans, Ellen Gommé, Debby Thomas, Godelieve Verbist, Miriam Mints, Eva Wardelmann, Michael R. Mallmann, Leonardus F. Massuger, Ronald P. Zweemer, Carole Mestdagh, Maciej Stukan, Helga B. Salvesen, Farid Moinfar, Johannes Haybaeck, Olli Carpén, Jutta Huvila, Pavel Dundr, Michal Zikan, Mariël Brinkhuis, Roy P.M. Kruitwagen, Koen Van de Vijver, Angel Garcia-Jimenez, Eva Colas, Natalja ter Haar, Jone Trovik, An Coosemans, Daniela Annibali, Tine Cuppens
Immunohistochemistry stainings of potential targets.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4086f6cbeb5ee0efad5a0a276e4729b8
https://doi.org/10.1158/1078-0432.22466298.v1
https://doi.org/10.1158/1078-0432.22466298.v1
Autor:
Frédéric Amant, Tjalling Bosse, Philippe Moerman, Els Hermans, Ellen Gommé, Debby Thomas, Godelieve Verbist, Miriam Mints, Eva Wardelmann, Michael R. Mallmann, Leonardus F. Massuger, Ronald P. Zweemer, Carole Mestdagh, Maciej Stukan, Helga B. Salvesen, Farid Moinfar, Johannes Haybaeck, Olli Carpén, Jutta Huvila, Pavel Dundr, Michal Zikan, Mariël Brinkhuis, Roy P.M. Kruitwagen, Koen Van de Vijver, Angel Garcia-Jimenez, Eva Colas, Natalja ter Haar, Jone Trovik, An Coosemans, Daniela Annibali, Tine Cuppens
High-grade endometrial stromal sarcoma with YMHAE/NUTM2A/B fusion and cyclin D1 expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96a9961790ab493ec157a3a7ebdb3768
https://doi.org/10.1158/1078-0432.22466292
https://doi.org/10.1158/1078-0432.22466292
Autor:
Carol J. Bult, Atul J. Butte, Helen Parkinson, Marcel Kool, Stefan M. Pfister, Frédéric Amant, S. John Weroha, Alana Welm, David M. Weinstock, Robert J. Wechsler-Reya, Emilie Vinolo, Livio Trusolino, Je Kyung Seong, Oscar M. Rueda, Daniel S. Peeper, James M. Olson, Steven B. Neuhauser, Enzo Medico, Jeremy Mason, K.C. Kent Lloyd, Michael T. Lewis, Tin O. Khor, Kristel Kemper, Jos Jonkers, Peter J. Houghton, Els Hermans, Melissa A. Haendel, Danielle Greenawalt, Neal C. Goodwin, Kristopher K. Frese, Stephane Ferretti, Yvonne A. Evrard, Olivier Duchamp, James H. Doroshow, Jonathan R. Dry, Heidi Dowst, Dominic A. Clark, Amanda L. Christie, Carlos Caldas, Annette T. Byrne, Matthew H. Brush, Alejandra Bruna, Andrea Bertotti, Debra M. Krupke, Dale A. Begley, Patrick Dunn, Jeffrey A. Wiser, Zhiping Gu, Sebastian Brabetz, Mark A. Murakami, Giorgio Inghirami, Theodore Goldstein, Nathalie Conte, Terrence F. Meehan
Patient-derived tumor xenograft (PDX) mouse models have emerged as an important oncology research platform to study tumor evolution, mechanisms of drug response and resistance, and tailoring chemotherapeutic approaches for individual patients. The la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0373627dabe0ae72d83c81ddf8478d17
https://doi.org/10.1158/0008-5472.c.6510291.v1
https://doi.org/10.1158/0008-5472.c.6510291.v1
Autor:
Frédéric Amant, Tjalling Bosse, Philippe Moerman, Els Hermans, Ellen Gommé, Debby Thomas, Godelieve Verbist, Miriam Mints, Eva Wardelmann, Michael R. Mallmann, Leonardus F. Massuger, Ronald P. Zweemer, Carole Mestdagh, Maciej Stukan, Helga B. Salvesen, Farid Moinfar, Johannes Haybaeck, Olli Carpén, Jutta Huvila, Pavel Dundr, Michal Zikan, Mariël Brinkhuis, Roy P.M. Kruitwagen, Koen Van de Vijver, Angel Garcia-Jimenez, Eva Colas, Natalja ter Haar, Jone Trovik, An Coosemans, Daniela Annibali, Tine Cuppens
Purpose: Uterine sarcomas are rare and heterogeneous tumors characterized by an aggressive clinical behavior. Their high rates of recurrence and mortality point to the urgent need for novel targeted therapies and alternative treatment strategies. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29504c2dc4024fc362457e1b48aad8c9
https://doi.org/10.1158/1078-0432.c.6526281
https://doi.org/10.1158/1078-0432.c.6526281
Autor:
Carol J. Bult, Atul J. Butte, Helen Parkinson, Marcel Kool, Stefan M. Pfister, Frédéric Amant, S. John Weroha, Alana Welm, David M. Weinstock, Robert J. Wechsler-Reya, Emilie Vinolo, Livio Trusolino, Je Kyung Seong, Oscar M. Rueda, Daniel S. Peeper, James M. Olson, Steven B. Neuhauser, Enzo Medico, Jeremy Mason, K.C. Kent Lloyd, Michael T. Lewis, Tin O. Khor, Kristel Kemper, Jos Jonkers, Peter J. Houghton, Els Hermans, Melissa A. Haendel, Danielle Greenawalt, Neal C. Goodwin, Kristopher K. Frese, Stephane Ferretti, Yvonne A. Evrard, Olivier Duchamp, James H. Doroshow, Jonathan R. Dry, Heidi Dowst, Dominic A. Clark, Amanda L. Christie, Carlos Caldas, Annette T. Byrne, Matthew H. Brush, Alejandra Bruna, Andrea Bertotti, Debra M. Krupke, Dale A. Begley, Patrick Dunn, Jeffrey A. Wiser, Zhiping Gu, Sebastian Brabetz, Mark A. Murakami, Giorgio Inghirami, Theodore Goldstein, Nathalie Conte, Terrence F. Meehan
A figure showing the process of generating and using PDX models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e07c88d40f7248397f4cc8053bf7da
https://doi.org/10.1158/0008-5472.22419099
https://doi.org/10.1158/0008-5472.22419099
Autor:
Frédéric Amant, Tjalling Bosse, Philippe Moerman, Els Hermans, Ellen Gommé, Debby Thomas, Godelieve Verbist, Miriam Mints, Eva Wardelmann, Michael R. Mallmann, Leonardus F. Massuger, Ronald P. Zweemer, Carole Mestdagh, Maciej Stukan, Helga B. Salvesen, Farid Moinfar, Johannes Haybaeck, Olli Carpén, Jutta Huvila, Pavel Dundr, Michal Zikan, Mariël Brinkhuis, Roy P.M. Kruitwagen, Koen Van de Vijver, Angel Garcia-Jimenez, Eva Colas, Natalja ter Haar, Jone Trovik, An Coosemans, Daniela Annibali, Tine Cuppens
Supplementary tables and figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696a528a2115d35f5032cb9ae4f9fd62
https://doi.org/10.1158/1078-0432.22466304.v1
https://doi.org/10.1158/1078-0432.22466304.v1