Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Els Goetghebeur"'
Autor:
Alfred Kipyegon Keter, Lutgarde Lynen, Alastair Van Heerden, Emily Wong, Klaus Reither, Els Goetghebeur, Bart K. M. Jacobs
Publikováno v:
PLoS ONE, Vol 18, Iss 3 (2023)
Diagnostic accuracy studies in pulmonary tuberculosis (PTB) are complicated by the lack of a perfect reference standard. This limitation can be handled using latent class analysis (LCA), assuming independence between diagnostic test results condition
Externí odkaz:
https://doaj.org/article/1de18e7f8b9840aba713205ec3cf1b85
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Polygenic risk scores (PRS) could potentially improve breast cancer screening recommendations. Before a PRS can be considered for implementation, it needs rigorous evaluation, using performance measures that can inform about its f
Externí odkaz:
https://doaj.org/article/edc3530cb55c4760b83756adf634b062
Autor:
Alfred Kipyegon Keter, Lutgarde Lynen, Alastair Van Heerden, Els Goetghebeur, Bart K.M. Jacobs
Publikováno v:
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, Vol 29, Iss , Pp 100331- (2022)
Background: In application studies of latent class analysis (LCA) evaluating imperfect diagnostic tests, residual dependence among the diagnostic tests still remain even after conditioning on the true disease status due to measured variables known to
Externí odkaz:
https://doaj.org/article/38ae567df1ae4f03958569ee7cc7d469
Autor:
Mathieu Spaas, Nora Sundahl, Eva Hulstaert, Vibeke Kruse, Sylvie Rottey, Daan De Maeseneer, Veerle Surmont, Annabel Meireson, Lieve Brochez, Dries Reynders, Els Goetghebeur, Robbe Van den Begin, Dirk Van Gestel, Vincent Renard, Piet Dirix, Pieter Mestdagh, Piet Ost
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background While the introduction of checkpoint inhibitors (CPIs) as standard of care treatment for various tumor types has led to considerable improvements in clinical outcome, the majority of patients still fail to respond. Preclinical dat
Externí odkaz:
https://doaj.org/article/e63e874a32664919a1b011b24efc5c07
Publikováno v:
BMJ Open, Vol 11, Iss 5 (2021)
Objective To evaluate the consistency of causal statements in observational studies published in The BMJ.Design Review of observational studies published in a general medical journal.Data source Cohort and other longitudinal studies describing an exp
Externí odkaz:
https://doaj.org/article/645891efef154255b6a5d06c712a5243
Autor:
Jimmy Van den Eynden, Tine Descamps, Els Delporte, Nancy H. C. Roosens, Sigrid C. J. De Keersmaecker, Vanessa De Wit, Joris Robert Vermeesch, Els Goetghebeur, Jean Tafforeau, Stefaan Demarest, Marc Van den Bulcke, Herman Van Oyen
Publikováno v:
Human Genomics, Vol 12, Iss 1, Pp 1-9 (2018)
Abstract Background National and international efforts like the 1000 Genomes Project are leading to increasing insights in the genetic structure of populations worldwide. Variation between different populations necessitates access to population-based
Externí odkaz:
https://doaj.org/article/61790fab15f54f909a204bbef0d23b5b
Autor:
Katrien De Wolf, Sylvie Rottey, Karim Vermaelen, Karel Decaestecker, Nora Sundahl, Lizzy De Lobel, Els Goetghebeur, Gert De Meerleer, Nicolaas Lumen, Valérie Fonteyne, Daan De Maeseneer, Piet Ost
Publikováno v:
Radiation Oncology, Vol 12, Iss 1, Pp 1-8 (2017)
Abstract Background The primary objective was to determine maximum tolerated radiation dose in patients with metastatic renal cell carcinoma on pazopanib treatment. Methods Treatment-naïve patients received pazopanib according to standard of care. S
Externí odkaz:
https://doaj.org/article/685cfaa7f347445d9a7e5a91558352c1
Autor:
Nora Sundahl, Katrien De Wolf, Sylvie Rottey, Karel Decaestecker, Daan De Maeseneer, Annabel Meireson, Els Goetghebeur, Valérie Fonteyne, Sofie Verbeke, Pieter De Visschere, Dries Reynders, Mireille Van Gele, Lieve Brochez, Piet Ost
Publikováno v:
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-9 (2017)
Abstract Background Current first-line standard of therapy for metastatic urothelial carcinoma is platinum-based combination chemotherapy. Pembrolizumab in phase III has demonstrated a promising overall response rate of 21.1% in patients with progres
Externí odkaz:
https://doaj.org/article/3b897c191b3b4860aea23e21cb164730
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153082 (2016)
When profiling hospital performance, quality inicators are commonly evaluated through hospital-specific adjusted means with confidence intervals. When identifying deviations from a norm, large hospitals can have statistically significant results even
Externí odkaz:
https://doaj.org/article/01d94c0b53124726ab59f8f58633414c
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e47112 (2012)
While many decisions rely on real time quantitative PCR (qPCR) analysis few attempts have hitherto been made to quantify bounds of precision accounting for the various sources of variation involved in the measurement process. Besides influences of mo
Externí odkaz:
https://doaj.org/article/ed2f73277d874663b9b531b524729474