Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Els Ampe"'
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Akademický článek
First‐in‐human development of a pharmacodynamic biomarker for PAC1 receptor antagonists using intradermal injections of maxadilan
Autor: Heleen Marynissen, Linde Buntinx, Dorien Bamps, Marleen Depre, Els Ampe, Anne Van Hecken, Kristin Gabriel, Steve Sands, Gabriel Vargas, Jan de Hoon
Publikováno v: Clinical and Translational Science, Vol 15, Iss 8, Pp 1968-1977 (2022)
Abstract Maxadilan, a potent vasodilator peptide, selectively activates the PAC1 receptor, a promising target for migraine therapy. Therefore, maxadilan has been suggested as a tool to study the pharmacodynamics (PDs) of PAC1 receptor antagonists. Th
Externí odkaz: https://doaj.org/article/5f31137aa46647bc88467882c8d81c9b
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2
Akademický článek
Co-creation with research participants to inform the design of electronic informed consent
Autor: Evelien De Sutter, David Geerts, Pascal Borry, Kristien Coteur, Dorien Bamps, Heleen Marynissen, Els Ampe, Els Geenens, Marleen Depré, Isabelle Huys
Publikováno v: Digital Health, Vol 8 (2022)
Objective This study aimed to provide recommendations for a personalized electronic informed consent interface that is adapted to research participants’ needs and could enable a longitudinal interaction between the participants and the research tea
Externí odkaz: https://doaj.org/article/275a31dc12574d1384db75d79a135ed1
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3
Pharmacokinetics of Oral Rebaudioside A in Patients with Type 2 Diabetes Mellitus and Its Effects on Glucose Homeostasis: A Placebo-Controlled Crossover Trial
Autor: Caroline Simoens, Koenraad Philippaert, Caroline Wuyts, Séverine Goscinny, Els Van Hoeck, Joris Van Loco, Jaak Billen, Jan de Hoon, Els Ampe, Roman Vangoitsenhoven, Ann Mertens, Rudi Vennekens, Bart Van der Schueren
Publikováno v: European Journal of Drug Metabolism and Pharmacokinetics. 47:827-839
Background and Objectives Rebaudioside A, a steviol glycoside, is deglycosylated by intestinal microflora prior to the absorption of steviol and conjugation to steviol glucuronide. While glucose-lowering properties are observed for rebaudioside A in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5596e6cf72d14809bfd178f88ce3b687
https://doi.org/10.1007/s13318-022-00792-7
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6
Implementation of a protocol for administration of vancomycin by continuous infusion: pharmacokinetic, pharmacodynamic and toxicological aspects
Autor: Els Ampe, Jean-Daniel Hecq, Bénédicte Delaere, Paul M. Tulkens, Youri Glupczynski
Publikováno v: International Journal of Antimicrobial Agents. 41:439-446
Optimising antibiotic administration is critical when dealing with pathogens with reduced susceptibility. Vancomycin activity is dependent on the area under the concentration-time curve over 24 h at steady-state divided by the minimum inhibitory conc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d7bb7b4eaa2bf8cfec8d15a06b5203
https://doi.org/10.1016/j.ijantimicag.2013.01.009
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8
Correlation between free and total vancomycin serum concentrations in patients treated for Gram-positive infections
Autor: Karine Berthoin, Els Ampe, Stéphane Carryn, Paul M. Tulkens
Publikováno v: International Journal of Antimicrobial Agents
International Journal of Antimicrobial Agents, Elsevier, 2009, 34 (6), pp.555. ⟨10.1016/j.ijantimicag.2009.08.005⟩
International audience; Routine therapeutic drug monitoring (TDM) reports only total vancomycin (VAN) concentrations, although protein binding varies and it is generally accepted that only free VAN is active. The aims of this study were to examine th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e19eb2f332fbb4d85a6af26e8005029
https://hal.archives-ouvertes.fr/hal-00556360/file/PEER_stage2_10.1016%2Fj.ijantimicag.2009.08.005.pdf
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