Výsledky vyhledávání - "Els A van der Wouden"

Does Angiotensin (1-7) Contribute to the Antiproteinuric Effect of ACE-inhibitors?

Autor: Leo E. Deelman, Dick de Zeeuw, Els A van der Wouden, Frans Boomsma, Anton J.M. Roks, Robert H. Henning

Publikováno v: Journal of the Renin-Angiotensin-Aldosterone System, Vol 6 (2005)
Journal of the Renin-Angiotensin-Aldosterone System, 6(2), 96-101. SAGE Publications Ltd
Journal of the Renin-Angiotensin-Aldosterone System, 6(2), 96-101

Angiotensin-converting enzyme inhibitors (ACE-I) reduce proteinuria and protect the kidney in proteinuric renal disease. During ACE-I therapy, circulating levels of angiotensin (1-7) [Ang (1-7)] are increased. As cardiac and renal protective effects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f176f6d1cfd42ba6d16df111ae8b07b
https://doi.org/10.3317/jraas.2005.016

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Approaches and methods in gene therapy for kidney disease

Autor: Els A van der Wouden, Dick de Zeeuw, Leo E. Deelman, Robert H. Henning, Maria Sandovici

Publikováno v: Journal of Pharmacological and Toxicological Methods, 50(1), 13-24

Renal gene therapy may offer new strategies to treat diseases of native and transplanted kidneys. Several experimental techniques have been developed and employed using nonviral, viral, and cellular vectors. The most efficient vector for in vivo tran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4a10a91fe6fbea7c86439bbcf6a1d6
https://hdl.handle.net/11370/2678a12e-602f-44e0-a351-6d0b74f6a76e

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Targeting of doxorubicin to the urinary bladder of the rat shows increased cytotoxicity in the bladder urine combined with an absence of renal toxicity

Autor: Frits Moolenaar, Dick de Zeeuw, Els A van der Wouden, M Haas, Paul E. de Jong, Dirk K. F. Meijer, Angela Elsinga

Publikováno v: Journal of Drug Targeting, 10(1), 81-89. TAYLOR & FRANCIS LTD

Targeting of anti-tumor drugs to the urinary bladder for the treatment of bladder carcinoma may be useful, since these agents generally have a low degree of urinary excretion and are highly toxic elsewhere in the body. The anti-tumor drug doxorubicin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e215e842be4088b95fd1082628ead82c
https://research.rug.nl/en/publications/2d020014-fe39-47a1-9ad8-7a234c6d0e9e

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Extracorporeal elimination in acute valproate intoxication

Autor: Angela Dekkers, David H Tjan, Hannah M E Kruis, Els A van der Wouden, Geert W Feith, Ingeborg M. van Geijlswijk

Publikováno v: BMJ Case Reports, pp. 10.1136/bcr.06.2008.0337-10.1136/bcr.06.2008.0337
BMJ Case Reports, 10.1136/bcr.06.2008.0337-10.1136/bcr.06.2008.0337
STARTPAGE=10.1136/bcr.06.2008.0337;ENDPAGE=10.1136/bcr.06.2008.0337;ISSN=1757-790X;TITLE=BMJ Case Reports

Severe poisoning with valproate may result in coma and death. The management of valproate intoxication is principally supportive. Valproate is scarcely excreted renally and is mainly protein bound and, therefore, not considered to be amenable for ext

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9777b4f27aca2d10c059d55ebe9c18b
https://hdl.handle.net/2066/80711

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TGF-beta Inhibits Ang II-Induced MAPK p44/42 Signaling in Vascular Smooth Muscle Cells by Ang II Type 1 Receptor Downregulation

Autor: Kumar Sharma, Vincent Pelgrom, Bernadet D. M. Meijering, Els A van der Wouden, Robert H. Henning, Leo E. Deelman

Publikováno v: Journal of vascular research, 46(5), 459-468. KARGER
Journal of Vascular Research, 46, 5, pp. 459-68
Journal of Vascular Research, 46, 459-68

Vascular changes in diabetes are characterized by reduced vasoconstriction and vascular remodeling. Previously, we demonstrated that TGF-β1 impairs Ang II-induced contraction through reduced calcium mobilization. However, the effect of TGF-β1 on An

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aaac7f18c2ae6bbebbf258e0555e0ce
https://research.rug.nl/en/publications/b432d5d3-268b-4ddb-8544-0ed7ec6ce54e

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The role of angiotensin(1-7) in renal vasculature of the rat

Autor: Richard P. E. van Dokkum, Leo E. Deelman, Robert H. Henning, Anton J.M. Roks, Dick de Zeeuw, Peter Ochodnický, Els A van der Wouden

Publikováno v: Journal of Hypertension, 24(10), 1971-1978. LIPPINCOTT WILLIAMS & WILKINS
Journal of hypertension, 24(10), 1971-1978. Lippincott Williams and Wilkins

Objective Angiotensin(1-7) is an active component of the renin-angiotensin-aldosterone system. Its exact role in renal vascular function is unclear. We therefore studied the effects of angiotensin(1-7) on the renal vasculature in vitro and in vivo.Me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e9908b62f416c1798171d2ad6a57d2e
https://pubmed.ncbi.nlm.nih.gov/16957547

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