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Antiplatelet activity of astaxanthin in control- and high cholesterol-fed rats mediated by down-regulation of P2Y 12 , inhibition of NF-κB, and increasing intracellular levels of cAMP.

Autor: Satti HH; Department of Pathology, College of Medicine, King Khalid University, Abha, Kingdom of Saudi Arabia.; Department of Pathology, University of Khartoum, Khartoum, Sudan., Khaleel EF; Department of Medical Physiology, College of Medicine, King Khalid University, Abha, Kingdom of Saudi Arabia.; Faculty of Medicine, Department of Medical Physiology, Cairo University, Cairo, Egypt., Badi RM; Department of Medical Physiology, College of Medicine, King Khalid University, Abha, Kingdom of Saudi Arabia.; Faculty of Medicine, Department of Physiology, University of Khartoum, Khartoum, Sudan., Elrefaie AO; Department of Pathology, College of Medicine, King Khalid University, Abha, Kingdom of Saudi Arabia.; National Liver Institute, Department of Pathology, Menoufyia University, Menoufyia, Egypt., Mostafa DG; Department of Medical Physiology, College of Medicine, King Khalid University, Abha, Kingdom of Saudi Arabia.; Faculty of Medicine, Department of Medical Physiology, Assiut University, Assiut, Egypt.

Publikováno v: Platelets [Platelets] 2021 May 19; Vol. 32 (4), pp. 469-478. Date of Electronic Publication: 2020 May 07.