Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Elpetra P. M. Timmermans-Sprang"'
Autor:
Marit F. van denBerg, Nicole Bechmann, Hans S. Kooistra, Monique E. vanWolferen, Elpetra P. M. Timmermans‐Sprang, Mirko Peitzsch, Sara Galac
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 5, Pp 2415-2424 (2024)
Abstract Background In humans with pheochromocytomas (PCCs), targeted metabolomics is used to determine the catecholamine phenotype or to uncover underlying pathogenic variants in tricarboxylic acid (TCA) cycle genes such as succinate dehydrogenase s
Externí odkaz:
https://doaj.org/article/d5bceac4709040d7a514d59aecc5b2f3
Autor:
Marit F. van den Berg, Hans S. Kooistra, Guy C. M. Grinwis, Stefano Nicoli, Stefania Golinelli, Lisa Stammeleer, Monique E. van Wolferen, Elpetra P. M. Timmermans-Sprang, Maurice M. J. M. Zandvliet, Frank G. van Steenbeek, Sara Galac
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
Pheochromocytomas and paragangliomas (PPGLs) are neuroendocrine tumors arising from the chromaffin cells in the adrenal medulla and extra-adrenal paraganglia, respectively. Local invasion, concurrent disorders, and metastases prevent surgical removal
Externí odkaz:
https://doaj.org/article/ca944eb626eb4e2cbd95c12dc7d0b599
Autor:
Karin Sanders, Anouk Veldhuizen, Hans S. Kooistra, Adri Slob, Elpetra P. M. Timmermans-Sprang, Frank M. Riemers, Sylvie Daminet, Federico Fracassi, Sebastiaan A. van Nimwegen, Björn P. Meij, Sara Galac
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
Canine Cushing's syndrome (hypercortisolism) can be caused by a pituitary tumor (pituitary-dependent hypercortisolism; PDH) or a cortisol-secreting adrenocortical tumor (csACT). For both cases, non-invasive biomarkers that could pre-operatively predi
Externí odkaz:
https://doaj.org/article/269ddf2aae4b4e2c8678a767f0a369a1
Autor:
Gayathri Thevi Selvarajah, Floor A. S. Bonestroo, Elpetra P. M. Timmermans Sprang, Jolle Kirpensteijn, Jan A. Mol
Publikováno v:
BMC Veterinary Research, Vol 13, Iss 1, Pp 1-8 (2017)
Abstract Background Quantitative PCR (qPCR) is a common method for quantifying mRNA expression. Given the heterogeneity present in tumor tissues, it is crucial to normalize target mRNA expression data using appropriate reference genes that are stably
Externí odkaz:
https://doaj.org/article/b3d24503881643bb86c2cca190fa8b3d
Autor:
Adri Slob, Anouk Veldhuizen, Hans S. Kooistra, Federico Fracassi, Sylvie Daminet, Elpetra P. M. Timmermans-Sprang, Sara Galac, Karin Sanders, Björn P. Meij, Sebastiaan A. van Nimwegen, Frank M. Riemers
Canine Cushing’s syndrome (hypercortisolism) can be caused by a pituitary tumor (pituitary-dependent hypercortisolism; PDH) or a cortisol-secreting adrenocortical tumor (csACT). For both cases, noninvasive biomarkers that could pre-operatively pred
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::437192f7e82b7caa1dfba930664dfc13
https://doi.org/10.1101/2021.08.17.456598
https://doi.org/10.1101/2021.08.17.456598
Autor:
Ana Gracanin, Elpetra P M Timmermans-Sprang, Monique E van Wolferen, Nagesha A S Rao, Juraj Grizelj, Silvijo Vince, Eva Hellmen, Jan A Mol
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98698 (2014)
Pet dogs very frequently develop spontaneous mammary tumors and have been suggested as a good model organism for breast cancer research. In order to obtain an insight into underlying signaling mechanisms during canine mammary tumorigenesis, in this s
Externí odkaz:
https://doaj.org/article/0e0f2de4802c4d708ebb819d82d38b54
Publikováno v:
Thyroid. 12:571-575
The etiopathogenesis of feline thyrotoxicosis is unknown. The transmembrane part (gene codons 480-640) of the thyrotropin receptor (TSHR) gene of hyperthyroid cats has already been investigated for the presence of stimulating mutations. No mutations
Publikováno v:
Domestic animal endocrinology. 34(4)
The gene encoding growth hormone (GH) is expressed not only in the pituitary but also in a variety of non-pituitary tissues. In the female dog, progestins are known to stimulate GH expression in the mammary gland. In order to investigate the regulati
Autor:
Ilse K, van Vonderen, Hans S, Kooistra, Elpetra P M, Timmermans-Sprang, Björn P, Meij, Ad, Rijnberk
Publikováno v:
Journal of veterinary internal medicine. 18(6)
Common disorders of water homeostasis leading to polyuria include a variety of endocrine, metabolic, and renal disturbances. After exclusion of most of these conditions, the diagnostic dilemma of differentiating between central diabetes insipidus, pr
Autor:
Elpetra P. M. Timmermans-Sprang, Jan A. Mol, Jolle Kirpensteijn, Gerard R. Rutteman, Irma S Lantinga-van Leeuwen, Evert van Garderen
Publikováno v:
Molecular and cellular endocrinology. 197(1-2)
The indirect growth-promoting action of pituitary-derived growth hormone (GH) on skeletal growth is thought to be mediated by systemically released insulin-like growth factor-I (IGF-I) and by locally produced IGF-I. The aim of the present study was t