Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Eloy F. Robles"'
Autor:
Eloy F. Robles, Maria Mena-Varas, Laura Barrio, Sara V. Merino-Cortes, Péter Balogh, Ming-Qing Du, Takashi Akasaka, Anton Parker, Sergio Roa, Carlos Panizo, Idoia Martin-Guerrero, Reiner Siebert, Victor Segura, Xabier Agirre, Laura Macri-Pellizeri, Beatriz Aldaz, Amaia Vilas-Zornoza, Shaowei Zhang, Sarah Moody, Maria Jose Calasanz, Thomas Tousseyn, Cyril Broccardo, Pierre Brousset, Elena Campos-Sanchez, Cesar Cobaleda, Isidro Sanchez-Garcia, Jose Luis Fernandez-Luna, Ricardo Garcia-Muñoz, Esther Pena, Beatriz Bellosillo, Antonio Salar, Maria Joao Baptista, Jesús Maria Hernandez-Rivas, Marcos Gonzalez, Maria Jose Terol, Joan Climent, Antonio Ferrandez, Xavier Sagaert, Ari M. Melnick, Felipe Prosper, David G. Oscier, Yolanda R. Carrasco, Martin J. S. Dyer, Jose A. Martinez-Climent
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
The homeobox NKX2 family of transcriptional factors has been shown to regulate fundamental developmental processes. Here, the authors show that NKX2-3 is a bona fideoncogenic driver in marginal-zone B-cell lymphoma and that it promotes lymphomagenesi
Externí odkaz:
https://doaj.org/article/8577d51efbf14e6384756140937ba872
Autor:
Jon Celay, Teresa Lozano, Axel R. Concepcion, Elena Beltrán, Francesc Rudilla, María José García-Barchino, Eloy F. Robles, Obdulia Rabal, Irene de Miguel, Carlos Panizo, Noelia Casares, Julen Oyarzabal, Jesús Prieto, Juan F. Medina, Juan José Lasarte, José Ángel Martínez-Climent
Publikováno v:
Haematologica, Vol 103, Iss 6 (2018)
Regulatory T (Treg) cells can weaken antitumor immune responses, and inhibition of their function appears to be a promising therapeutic approach in cancer patients. Mice with targeted deletion of the gene encoding the Cl−/HCO3− anion exchanger AE
Externí odkaz:
https://doaj.org/article/25a1ce682baf49a699ef7d52c130573e
Autor:
Francesca Rapino, Eloy F. Robles, Jose A. Richter-Larrea, Eric M. Kallin, Jose A. Martinez-Climent, Thomas Graf
Publikováno v:
Cell Reports, Vol 3, Iss 4, Pp 1153-1163 (2013)
Earlier work demonstrated that the transcription factor C/EBPα can convert immature and mature murine B lineage cells into functional macrophages. Testing >20 human lymphoma and leukemia B cell lines, we found that most can be transdifferentiated at
Externí odkaz:
https://doaj.org/article/ebef9f95d9b541daab913c4c1d5ee4cf
Autor:
Francesca Rapino, Eloy F. Robles, Jose A. Richter-Larrea, Eric M. Kallin, Jose A. Martinez-Climent, Thomas Graf
Publikováno v:
Cell Reports, Vol 19, Iss 6, p 1281 (2017)
Externí odkaz:
https://doaj.org/article/63f4a2615d3b4f398a0b464634493f4b
Autor:
Raquel Malumbres, Vicente Fresquet, Jose Roman-Gomez, Miriam Bobadilla, Eloy F. Robles, Giovanna G. Altobelli, M.ª José Calasanz, Erlend B. Smeland, Maria Angela Aznar, Xabier Agirre, Vanesa Martin-Palanco, Felipe Prosper, Izidore S. Lossos, Jose A. Martinez-Climent
Publikováno v:
Haematologica, Vol 96, Iss 7 (2011)
Background LMO2 is highly expressed at the most immature stages of lymphopoiesis. In T-lymphocytes, aberrant LMO2 expression beyond those stages leads to T-cell acute lymphoblastic leukemia, while in B cells LMO2 is also expressed in germinal center
Externí odkaz:
https://doaj.org/article/5617bccc3c094e54a13ca3cdccc7b302
Autor:
Ari Melnick, Jose A. Martinez-Climent, Oscar Blanco, Eloy F. Robles, Jose I. Martinez-Ferrandis, Alvaro Martínez-Baztan, Davide Bagnara, Jon Celay, Maria-Jose Garcia-Barchino, Stephen Meier, Diego Alignani, Carlos Panizo, Thomas MacCarthy, Ainara Sagardoy, Marien Pascual, Xavier Sagaert, Sandra Hervas-Stubbs, Maria Mena-Varas, Sergio Roa, Karen L. Bunting, Noelia Casares, Juan José Lasarte, Elizabeth Guruceaga
Publikováno v:
Blood
Refractory or relapsed diffuse large B-cell lymphoma (DLBCL) often associates with the activated B-cell-like (ABC) subtype and genetic alterations that drive constitutive NF-κB activation and impair B-cell terminal differentiation. Here, we show tha
Autor:
Felipe Prosper, Ana Balanzategui, María José Larrayoz, Miguel A. Piris, Jose A. Martinez-Climent, Shuhua Yi, Sebastian Böttcher, Ken H. Young, María José Calasanz, Victor Segura, Antonio Martinez, Blanca Gonzalez-Farre, Marta Larrayoz, Cristina Jimenez, Davide Rossi, Jesús F. San Miguel, Jesús M. Hernández-Rivas, Julie Morscio, María José García-Barchino, Mingzhi Zhang, María Eugenia Sarasquete, Thomas Tousseyn, Marcos González, Alberto Orfao, Zijun Y. Xu-Monette, Santiago Montes-Moreno, Noemi Puig-Moron, Jon Celay, Miguel Alcoceba, Idoia Rodriguez, Xavier Sagaert, Bruno Paiva, Eloy F. Robles, Carlos Panizo, Gianluca Gaidano, Jianyong Li, Ricardo García-Muñoz, Sergio Roa, Vicente Fresquet, M. Rabasa
Publikováno v:
The Journal of Pathology. 245:61-73
The increased risk of Richter transformation (RT) in patients with chronic lymphocytic leukaemia (CLL) due to Epstein-Barr virus (EBV) reactivation during immunosuppressive therapy with fludarabine other targeted agents remains controversial. Among 3
Autor:
María J. Delgado, María J. Torres, Emilio Bueno, Eloy F. Robles, Eulogio J. Bedmar, Tino Krell, Socorro Mesa
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Expression of the Bradyrhizobium japonicum napEDABC, nirK and norCBQD denitrification genes requires low oxygen (O2) tension and nitrate (NO3−), through a regulatory network comprised of two coordinated cascades, FixLJ-FixK2-NnrR and RegSR-NifA. To
Autor:
Maria J, García-Barchino, Maria E, Sarasquete, Carlos, Panizo, Julie, Morscio, Antonio, Martinez, Miguel, Alcoceba, Vicente, Fresquet, Blanca, Gonzalez-Farre, Bruno, Paiva, Ken H, Young, Eloy F, Robles, Sergio, Roa, Jon, Celay, Marta, Larrayoz, Davide, Rossi, Gianluca, Gaidano, Santiago, Montes-Moreno, Miguel A, Piris, Ana, Balanzategui, Cristina, Jimenez, Idoia, Rodriguez, Maria J, Calasanz, Maria J, Larrayoz, Victor, Segura, Ricardo, Garcia-Muñoz, Maria P, Rabasa, Shuhua, Yi, Jianyong, Li, Mingzhi, Zhang, Zijun Y, Xu-Monette, Noemi, Puig-Moron, Alberto, Orfao, Sebastian, Böttcher, Jesus M, Hernandez-Rivas, Jesus San, Miguel, Felipe, Prosper, Thomas, Tousseyn, Xavier, Sagaert, Marcos, Gonzalez, Jose A, Martinez-Climent
Publikováno v:
The Journal of pathology. 245(1)
The increased risk of Richter transformation (RT) in patients with chronic lymphocytic leukaemia (CLL) due to Epstein-Barr virus (EBV) reactivation during immunosuppressive therapy with fludarabine other targeted agents remains controversial. Among 3
Autor:
Jose A. Martinez-Climent, Béla Kajtár, Eloy F. Robles, Zoltán Kellermayer, Haruko Hayasaka, Péter Balogh, Diána Simon
Publikováno v:
International Reviews of Immunology. 35:489-502
Despite their functional similarities, peripheral lymphoid tissues are remarkably different according to their developmental properties and structural characteristics, including their specified vasculature. Access of leukocytes to these organs critic