Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Elona Kolpakova-Hart"'
Autor:
Bin Li, Hyunjin Shin, Georgy Gulbekyan, Olga Pustovalova, Yuri Nikolsky, Andrew Hope, Marina Bessarabova, Matthew Schu, Elona Kolpakova-Hart, David Merberg, Andrew Dorner, William L Trepicchio
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130700 (2015)
Development of drug responsive biomarkers from pre-clinical data is a critical step in drug discovery, as it enables patient stratification in clinical trial design. Such translational biomarkers can be validated in early clinical trial phases and ut
Externí odkaz:
https://doaj.org/article/ff7240e562214215af66645a587a6a86
Publikováno v:
Orthodontics & Craniofacial Research. 15:148-158
Objectives To investigate the anatomy of the mouse palate, the midpalatal suture, and the cellular characteristics in the sutures before and immediately after midpalatal suture expansion.
Autor:
Jing Zhou, Bjorn R. Olsen, Tatiana Y. Besschetnova, Jagesh V. Shah, Elona Kolpakova-Hart, Yinghua Guan
Publikováno v:
Current Biology. 20(2):182-187
SummaryThe primary cilium acts as a transducer of extracellular stimuli into intracellular signaling [1, 2]. Its regulation, particularly with respect to length, has been defined primarily by genetic experiments and human disease states in which mole
Publikováno v:
Bone. 44:1121-1133
Mechanical stress is known to modulate postnatal skeletal growth and development. However, the mechanisms underlying the mechanotransduction are not fully understood. Polycystin-1 (PC1) is a promising candidate among proteins that may play a role in
Autor:
Naomi Fukai, Claudia M. Nicolae, Bjorn R. Olsen, Brandeis McBratney-Owen, Jing Zhou, Elona Kolpakova-Hart, Bo Hou
Publikováno v:
Developmental Biology. 321(2):407-419
In vertebrates, coordinated embryonic and postnatal growth of the craniofacial bones and the skull base is essential during the expansion of the rostrum and the brain. Identification of molecules that regulate skull growth is important for understand
Publikováno v:
Developmental Biology. 309:273-284
Hedgehog signaling plays an essential role in patterning of the vertebrate skeleton. Here we demonstrate that conditional inactivation of the Kif3a subunit of the kinesin-2 intraflagellar transport motor in mesenchymal skeletal progenitor cells resul
Autor:
Hyunjin Shin, Bin Li, Olga Pustovalova, David Merberg, Andrew Hope, Marina Bessarabova, Elona Kolpakova-Hart, Andrew Dorner, Georgy Gulbekyan, Matthew Schu, Yuri Nikolsky, William L. Trepicchio
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 6, p e0130700 (2015)
PLoS ONE, Vol 10, Iss 6, p e0130700 (2015)
Development of drug responsive biomarkers from pre-clinical data is a critical step in drug discovery, as it enables patient stratification in clinical trial design. Such translational biomarkers can be validated in early clinical trial phases and ut
Publikováno v:
Matrix biology : journal of the International Society for Matrix Biology. 27(6)
Here we report on the severe defects in renal epithelium induced by the transgenic Col2-Cre line used previously for skeletal tissue-specific gene targeting. We demonstrate that conditional ablation of the Kif3a or Pkd1 genes encoding primary cilium/