Výsledky vyhledávání - "Eloise M Walker"

Akademický článek

Phosphodiesterase beta is the master regulator of cAMP signalling during malaria parasite invasion.

Autor: Christian Flueck, Laura G Drought, Andrew Jones, Avnish Patel, Abigail J Perrin, Eloise M Walker, Stephanie D Nofal, Ambrosius P Snijders, Michael J Blackman, David A Baker

Publikováno v: PLoS Biology, Vol 17, Iss 2, p e3000154 (2019)

Cyclic nucleotide signalling is a major regulator of malaria parasite differentiation. Phosphodiesterase (PDE) enzymes are known to control cyclic GMP (cGMP) levels in the parasite, but the mechanisms by which cyclic AMP (cAMP) is regulated remain en

Externí odkaz: https://doaj.org/article/f2dfa91a00fe4670be575d3637a30657

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Cyclic nucleotide signalling in malaria parasites

Autor: David A. Baker, Laura G. Drought, Christian Flueck, Stephanie D. Nofal, Avnish Patel, Maria Penzo, Eloise M. Walker

Publikováno v: Open Biology, Vol 7, Iss 12 (2017)

The cyclic nucleotides 3′, 5′-cyclic adenosine monophosphate (cAMP) and 3′, 5′-cyclic guanosine monophosphate (cGMP) are intracellular messengers found in most animal cell types. They usually mediate an extracellular stimulus to drive a chang

Externí odkaz: https://doaj.org/article/18f7548d2de1411f809790675d5bf748

Zobrazit plný text záznamu

Monocytes and Macrophages in Alpha-1 Antitrypsin Deficiency

Autor: Elizabeth Sapey, Kylie B. R. Belchamber, Eloise M Walker, Robert A. Stockley

Publikováno v: International Journal of Chronic Obstructive Pulmonary Disease. 15:3183-3192

Alpha-1 antitrypsin deficiency (AATD) is a genetic condition characterised by low circulating levels of alpha-1 antitrypsin (AAT), a serine proteinase inhibitor. The most common deficiency variants are the S and Z mutations, which cause the accumulat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::28d2d108702015f8d4fddb2a93c9e22f
https://doi.org/10.2147/copd.s276792

Zobrazit plný text záznamu

SARS-CoV-2 seroprevalence and asymptomatic viral carriage in healthcare workers: a cross-sectional study

Publikováno v: Thorax

ObjectiveTo determine the rates of asymptomatic viral carriage and seroprevalence of SARS-CoV-2 antibodies in healthcare workers.DesignA cross-sectional study of asymptomatic healthcare workers undertaken on 24/25 April 2020.SettingUniversity Hospita

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd27dd511f0616b3ed2ed8baf05196f
https://doi.org/10.1136/thoraxjnl-2020-215414

Zobrazit plný text záznamu

New Pharmacological Tools to Target Leukocyte Trafficking in Lung Disease

Autor: Michael J. Hughes, Kylie B. R. Belchamber, Elizabeth Sapey, Daniella A Spittle, Eloise M Walker

Publikováno v: Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)

Infection and inflammation of the lung results in the recruitment of non-resident immune cells, including neutrophils, eosinophils and monocytes. This swift response should ensure clearance of the threat and resolution of stimuli which drive inflamma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d0e5ea76923dfa9c9e00a44fa58bb59
http://europepmc.org/articles/PMC8334730

Zobrazit plný text záznamu

Mitigating Health Risks to Reopen a Clinical Research Laboratory During the COVID-19 Pandemic: A Framework (Preprint)

Autor: Eloise M Walker, Alice E Jasper, Lauren Davis, Kay Por Yip, Aduragbemi A Faniyi, Michael J Hughes, Helena A Crisford, Daniella A Spittle, Elizabeth Sapey, Kylie B R Belchamber, Aaron Scott

BACKGROUND The COVID-19 pandemic has led to many countries implementing lockdown procedures, resulting in the suspension of laboratory research. With lockdown measures now easing in some areas, many laboratories are preparing to reopen. This is parti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1a3a4d4cbea700760563f1e96b25617b
https://doi.org/10.2196/preprints.22570

Zobrazit plný text záznamu

Rapid implementation and validation of a cold-chain free SARS-CoV-2 diagnostic testing workflow to support surge capacity

Autor: Andrew Ellis, Alex G. Richter, Oliver J Pickles, Eloise M Walker, Gabriella L. Morley, Craig Webster, Kasun Wanigasooriya, Andrew D Beggs, Celina Whalley, Andrew Bosworth, Dee E McLoughlin, Danai Papakonstantinou, Charlie Poxon, Agnieszka E. Zielinska, Tim Plant, I. Michael Kidd, Erin L. Aldera

Publikováno v: Journal of Clinical Virology

Background In January 2020 reports of unidentified severe respiratory illness were described in Wuhan, China. A rapid expansion in cases affecting most countries around the globe led to major changes in the way people live their daily lives. In the U

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d1adabd63d038a04a27a64b8247e24
http://europepmc.org/articles/PMC7244439

Zobrazit plný text záznamu

Global genetic diversity of var2csa in Plasmodium falciparum with implications for malaria in pregnancy and vaccine development

Autor: Martin L. Hibberd, Jamille Gregório Dombrowski, Fady R. Mohareb, Susana Campino, Ernest Diez Benavente, Taane G. Clark, Cally Roper, Damilola R. Oresegun, David A. Baker, Claudio Romero Farias Marinho, Rodrigo Medeiros de Souza, Paola Florez de Sessions, Colin J. Sutherland, Eloise M. Walker

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scientific Reports

Malaria infection during pregnancy, caused by the sequestering of Plasmodium falciparum parasites in the placenta, leads to high infant mortality and maternal morbidity. The parasite-placenta adherence mechanism is mediated by the VAR2CSA protein, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b65356796101c0d9318d7f4fbb34813
http://link.springer.com/article/10.1038/s41598-018-33767-3

Zobrazit plný text záznamu