Combating lead and cadmium exposure with an orally administered chitosan-based chelating polymer

Autor: Jordyn Ann Howard, Halyna Kuznietsova, Natalia Dziubenko, Axel Aigle, Marco Natuzzi, Eloise Thomas, Vladimir Lysenko, Laurent David, Thomas Brichart, François Lux, Olivier Tillement

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)

Abstract Heavy metals present a threat to human health, even at minimal concentrations within the body. One source of exposure is due to the consumption of low-level contaminated foodstuff and water. Lead and cadmium have been shown to be absorbed by

Externí odkaz: https://doaj.org/article/b69cb96046ed4b189a0f251c00c544ea

3-Bromopyruvate-mediated MCT1-dependent metabolic perturbation sensitizes triple negative breast cancer cells to ionizing radiation

Autor: John Walsby-Tickle, Sarah Able, Joshua Owen, Abirami Lakshminarayanan, Katherine A. Vallis, Robert Carlisle, Eloise Thomas, Irini Skaripa-Koukelli, David Hauton, James S. O. McCullagh

Publikováno v: Cancer & Metabolism
Cancer & Metabolism, 2021, 9 (1), ⟨10.1186/s40170-021-00273-6⟩
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-17 (2021)

Background Triple negative breast cancer (TNBC) poses a serious clinical challenge as it is an aggressive form of the disease that lacks estrogen receptor, progesterone receptor, and ERBB2 (formerly HER2) gene amplification, which limits the treatmen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7de81ff163c079d823c356652877b842
https://hal.archives-ouvertes.fr/hal-03379071

Impact of Amblyopia on Visual Attention and Visual Search in Children

Autor: Eloise Thomas, Alex A. Black, Ann L. Webber, Silvie Hoang, Joanne M. Wood

Publikováno v: Investigative Ophthalmology & Visual Science

Purpose: The purpose of this study was to compare binocular visual attention, visual processing speeds, and visuo-cognitive search ability in children with and without amblyopia and investigate the association of visual acuity and binocular function

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c146ca95b2233b380d3944af2b0bd7
http://europepmc.org/articles/PMC8054626

68Ga-radiolabeled AGuIX nanoparticles as dual-modality imaging agents for PET/MRI-guided radiation therapy

Autor: Penelope Bouziotis, Anastasios Gaitanis, Eloise Thomas, Stavros Xanthopoulos, François Lux, Charles Truillet, Lia A. Moulopoulos, Dimitris Stellas, Vassilis Koutoulidis, Charalampos Tsoukalas, Theodoros Tsotakos, Maria Paravatou-Petsotas, Olivier Tillement, Constantinos Anagnostopoulos

Publikováno v: Nanomedicine
Nanomedicine, Future Medicine, 2017, 12 (13), pp.1561-1574. ⟨10.2217/nnm-2017-0032⟩

Aim: The aim of this study was to develop a dual-modality positron emission tomography/magnetic resonance (PET/MR) imaging probe by radiolabeling gadolinium-containing AGuIX derivatives with the positron-emitter Gallium-68 (68Ga). Materials & methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::571847380ae0a794d348321b916fcf91
https://doi.org/10.2217/nnm-2017-0032

AGuIX® from bench to bedside-Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine

Autor: Camille Verry, Awatef Allouch, Carolyn J. Anderson, Olivier Tillement, Cyrus Chargari, Nathalie Mignet, Benoit Larrat, Marc Janier, Jacqueline Sidi-Boumedine, Kevin M. Prise, Peter Fries, Bich-Thuy Doan, Erika Porcel, Fabien Rossetti, Jacques Balosso, Marie-Caline Abadjian, Dominique Ardail, Frédéric Boschetti, Yannick Crémillieux, Alexandre Detappe, Claire Rodriguez-Lafrasse, Ross Berbeco, Marie-Thérèse Aloy, Sébastien Mériaux, Vu Long Tran, Emmanuel L. Barbier, Sandrine Lacombe, Sandrine Dufort, Matteo Martini, Andreas Müller, Eric Deutsch, Karl T. Butterworth, Emmanuelle Canet-Soulas, Géraldine Le Duc, Franck Denat, Goran Angelovski, Guillaume Bort, Céline Frochot, Jean-Luc Perfettini, Eloise Thomas, Stéphane Roux, Tristan Doussineau, Muriel Barberi-Heyob, Michael J. Evans, François Lux, Charles Truillet, Stephen J. McMahon, Penelope Bouziotis

Publikováno v: The British journal of radiology, vol 92, iss 1093
British Journal of Radiology
British Journal of Radiology, 2019, 92 (1093), pp.20180365. ⟨10.1259/bjr.20180365⟩
British Journal of Radiology, British Institute of Radiology, 2019, 92 (1093), pp.20180365. ⟨10.1259/bjr.20180365⟩
The British Journal of Radiology
Lux, F, Tran, V L, Thomas, E, Dufort, S, Rossetti, F, Martini, M, Truillet, C, Doussineau, T, Bort, G, Denat, F, Boschetti, F, Angelovski, G, Detappe, A, Crémillieux, Y, Mignet, N, Doan, B-T, Larrat, B, Meriaux, S, Barbier, E, Roux, S, Fries, P, Müller, A, Abadjian, M-C, Anderson, C, Canet-Soulas, E, Bouziotis, P, Barberi-Heyob, M, Frochot, C, Verry, C, Balosso, J, Evans, M, Sidi-Boumedine, J, Janier, M, Butterworth, K, McMahon, S, Prise, K, Aloy, M-T, Ardail, D, Rodriguez-Lafrasse, C, Porcel, E, Lacombe, S, Berbeco, R, Allouch, A, Perfettini, J-L, Chargari, C, Deutsch, E, Le Duc, G & Tillement, O 2019, ' AGuIX® from bench to bedside-Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine ', British Journal of Radiology, vol. 92, no. 1093, 20180365 . https://doi.org/10.1259/bjr.20180365

International audience; AGuIX® are sub-5 nm nanoparticles made of a polysiloxane matrix and gadolinium chelates. This nanoparticle has been recently accepted in clinical trials in association with radiotherapy. This review will summarize the princip

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94088f237edf5a1f9b2fb1fad5071931
https://escholarship.org/uc/item/39f7b441