Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Eloi R. Verrier"'
Autor:
Valerio Taverniti, Laura Meiss-Heydmann, Cloé Gadenne, Hannah Vanrusselt, Dieudonné Buh Kum, Fabio Giannone, Patrick Pessaux, Catherine Schuster, Thomas F. Baumert, Yannick Debing, Eloi R. Verrier
Publikováno v:
JHEP Reports, Vol 6, Iss 10, Pp 101134- (2024)
Background & Aims: Chronic HBV infection is the leading cause of liver disease and of hepatocellular carcinoma. The improvement of antiviral therapy remains an unmet medical need. Capsid assembly modulators (CAMs) target the HBV core antigen (HBc) an
Externí odkaz:
https://doaj.org/article/6a35f09c18f042008a06b7ebb33fb53d
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The study enrolled 284 patients with chronic hepatitis B virus infection. Participants included people with mild fibrotic lesions (32.5%), moderate to severe fibrotic lesions (27.5%), cirrhotic lesions (22%), hepatocellular carcinoma (HCC) i
Externí odkaz:
https://doaj.org/article/cab850d967bc4f398999ca44affecbe3
Autor:
Emilie Crouchet, Simonetta Bandiera, Naoto Fujiwara, Shen Li, Hussein El Saghire, Mirian Fernández-Vaquero, Tobias Riedl, Xiaochen Sun, Hadassa Hirschfield, Frank Jühling, Shijia Zhu, Natascha Roehlen, Clara Ponsolles, Laura Heydmann, Antonio Saviano, Tongqi Qian, Anu Venkatesh, Joachim Lupberger, Eloi R. Verrier, Mozhdeh Sojoodi, Marine A. Oudot, François H. T. Duong, Ricard Masia, Lan Wei, Christine Thumann, Sarah C. Durand, Victor González-Motos, Danijela Heide, Jenny Hetzer, Shigeki Nakagawa, Atsushi Ono, Won-Min Song, Takaaki Higashi, Roberto Sanchez, Rosa S. Kim, C. Billie Bian, Karun Kiani, Tom Croonenborghs, Aravind Subramanian, Raymond T. Chung, Beate K. Straub, Detlef Schuppan, Maliki Ankavay, Laurence Cocquerel, Evelyne Schaeffer, Nicolas Goossens, Anna P. Koh, Milind Mahajan, Venugopalan D. Nair, Ganesh Gunasekaran, Myron E. Schwartz, Nabeel Bardeesy, Alex K. Shalek, Orit Rozenblatt-Rosen, Aviv Regev, Emanuele Felli, Patrick Pessaux, Kenneth K. Tanabe, Mathias Heikenwälder, Catherine Schuster, Nathalie Pochet, Mirjam B. Zeisel, Bryan C. Fuchs, Yujin Hoshida, Thomas F. Baumert
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Drug and target discovery for advanced liver disease are hampered by a lack of suitable models for clinical translation. Here the authors present a human liver cell-based system modeling a clinical prognostic signature allowing to propose nizatidine
Externí odkaz:
https://doaj.org/article/454d7d31ae1e40b7812cd73b90a2e7e3
Autor:
Magda Rybicka, Anna Woziwodzka, Alicja Sznarkowska, Tomasz Romanowski, Piotr Stalke, Marcin Dręczewski, Eloi R. Verrier, Thomas F. Baumert, Krzysztof Piotr Bielawski
Publikováno v:
International Journal of Infectious Diseases, Vol 96, Iss , Pp 260-265 (2020)
Objectives: The outcomes of hepatitis B virus (HBV) infection vary substantially among affected individuals, providing evidence of the role of host genetic background in the susceptibility to HBV persistence and the dynamics of liver injury progressi
Externí odkaz:
https://doaj.org/article/1c66a0150547457aac1af0b0cd251b49
Autor:
Carla Eller, Laura Heydmann, Che C. Colpitts, Houssein El Saghire, Federica Piccioni, Frank Jühling, Karim Majzoub, Caroline Pons, Charlotte Bach, Julie Lucifora, Joachim Lupberger, Michael Nassal, Glenn S. Cowley, Naoto Fujiwara, Sen-Yung Hsieh, Yujin Hoshida, Emanuele Felli, Patrick Pessaux, Camille Sureau, Catherine Schuster, David E. Root, Eloi R. Verrier, Thomas F. Baumert
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Here the authors perform a gain-of-function screen and identify CDKN2C as a host factor for HBV replication, inducing cell cycle arrest and expression of HBV transcription enhancers. CDKN2C expression correlates with disease progression suggesting a
Externí odkaz:
https://doaj.org/article/0742f94d66504c4986045226266777a1
Autor:
Nadine Laguette, Christelle Langevin, David Olagnier, Vincenzo Torraca, Claire Vanpouille-Box, Eloi R. Verrier
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/365956f1bf124362b6863c0bd17b499e
Autor:
Eloi R. Verrier, Christelle Langevin
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Innate immune pathways are the first line of cellular defense against pathogen infections ranging from bacteria to Metazoa. These pathways are activated following the recognition of pathogen associated molecular patterns (PAMPs) by membrane and cytos
Externí odkaz:
https://doaj.org/article/3a3a6f91d5e6441ea1672b474b5c99f9
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2787 (2022)
Chronic viral hepatitis is a main cause of liver disease and hepatocellular carcinoma. There are striking similarities in the pathological impact of hepatitis B, C, and D, although these diseases are caused by very different viruses. Paired with the
Externí odkaz:
https://doaj.org/article/49ca1eef790f47e9bfe615d3ad41a570
Autor:
Valerio Taverniti, Gaëtan Ligat, Yannick Debing, Dieudonne Buh Kum, Thomas F. Baumert, Eloi R. Verrier
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 5, p 1349 (2022)
Despite a preventive vaccine being available, more than 250 million people suffer from chronic hepatitis B virus (HBV) infection, a major cause of liver disease and HCC. HBV infects human hepatocytes where it establishes its genome, the cccDNA with c
Externí odkaz:
https://doaj.org/article/625bd3214e0f4aedb8f37cb5d8df4edf
Autor:
Eloi R. Verrier, Carine Genet, Denis Laloë, Florence Jaffrezic, Andrea Rau, Diane Esquerre, Nicolas Dechamp, Céline Ciobotaru, Caroline Hervet, Francine Krieg, Luc Jouneau, Christophe Klopp, Edwige Quillet, Pierre Boudinot
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-15 (2018)
Abstract Background The viral hemorrhagic septicemia virus (VHSV) is a major threat for salmonid farming and for wild fish populations worldwide. Previous studies have highlighted the importance of innate factors regulated by a major quantitative tra
Externí odkaz:
https://doaj.org/article/bd66f02a107f4020b116b0d576eb583d