Azaphilones Pigments from the Fungus Penicillium hirayamae

Autor: Coralie Pavesi, Victor Flon, Grégory Genta-Jouve, Elodie Pramil, Alexandre Escargueil, Adeel Nasir, Tristan Montier, Xavier Franck, Soizic Prado

Publikováno v: Colorants, Vol 2, Iss 1, Pp 31-41 (2023)

The use of fungal pigments as dyes is attractive for various industries. Fungal pigments arise a strong interest because they are suitable for large-scale industrial production and have none of the drawbacks of synthetic pigments. Their advantages ov

Externí odkaz: https://doaj.org/article/194771928d444422a5f4f907cb68e4ef

Distinction between 2′- and 3′-Phosphate Isomers of a Fluorescent NADPH Analogue Led to Strong Inhibition of Cancer Cells Migration

Autor: Raoul Manuel, Michelle de Souza Lima, Sébastien Dilly, Sylvain Daunay, Patricia Abbe, Elodie Pramil, Stéphanie Solier, Fabienne Guillaumond, Sarah-Simha Tubiana, Alexandre Escargueil, João Antonio Pêgas Henriques, Nathalie Ferrand, Irène Erdelmeier, Jean-Luc Boucher, Gildas Bertho, Israel Agranat, Stéphane Rocchi, Michèle Sabbah, Anny Slama Schwok

Publikováno v: Antioxidants, Vol 10, Iss 5, p 723 (2021)

Specific inhibition of NADPH oxidases (NOX) and NO-synthases (NOS), two enzymes associated with redox stress in tumor cells, has aroused great pharmacological interest. Here, we show how these enzymes distinguish between isomeric 2′- and 3′-phosp

Externí odkaz: https://doaj.org/article/84f91cba70544bcfae3bd010bb62d55a

Expression Pattern of Purinergic Signaling Components in Colorectal Cancer Cells and Differential Cellular Outcomes Induced by Extracellular ATP and Adenosine

Autor: Annette K. Larsen, Ammara Mohammad, Vincent Maréchal, Alexandre E. Escargueil, Laurent Jourdren, Chloé Borde, Virginie Puchois, Michèle Sabbah, Clémentine Dillard, Elodie Pramil

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 11472, p 11472 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences, MDPI, 2021, 22 (21), pp.11472. ⟨10.3390/ijms222111472⟩

International audience; The purine nucleotide adenosine triphosphate (ATP) is known for its fundamental role in cellular bioenergetics. However, in the last decades, different works have described emerging functions for ATP, such as that of a danger

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a97bae4cf2d62a140d0ec10074ea5a
https://pubmed.ncbi.nlm.nih.gov/34768902

The C-Terminal Acidic Tail Modulates the Anticancer Properties of HMGB1

Autor: Chloé Borde, Clémentine Dillard, Aurore L’Honoré, Frédérique Quignon, Marion Hamon, Christophe H. Marchand, Roberta Soares Faccion, Maurício G. S. Costa, Elodie Pramil, Annette K. Larsen, Michèle Sabbah, Stéphane D. Lemaire, Vincent Maréchal, Alexandre E. Escargueil

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 14; Pages: 7865

Energy metabolism reprogramming was recently listed as a hallmark of cancer. In this process, the switch from pyruvate kinase isoenzyme type M1 to pyruvate kinase isoenzyme type M2 (PKM2) is believed to play a crucial role. Interestingly, the activit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24356fa1e8dde548dbffd811add08d1f
https://doi.org/10.3390/ijms23147865

Targeting chronic lymphocytic leukemia with N-methylated thrombospondin-1–derived peptides overcomes drug resistance

Autor: Frederic Davi, Malina Xiao, Thomas Denèfle, Philippe Karoyan, Eva Lardé, Florence Nguyen-Khac, Santos A. Susin, Elise Chapiro, H. Merle-Beral, Damien Roos-Weil, Fariba Nemati, Karim Maloum, Didier Decaudin, Elodie Pramil, Magali Le Garff-Tavernier, Marika Sarfati, Linda Herbi Bastian

Publikováno v: Blood Advances
Blood Advances, The American Society of Hematology, 2019, 3 (20), pp.2920-2933. ⟨10.1182/bloodadvances.2019000350⟩

International audience; Chronic lymphocytic leukemia (CLL), the most common adulthood leukemia in Western countries, is a very heterogeneous disease characterized by a peripheral accumulation of abnormal CD5+ B lymphocytes in the immune system. Despi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b33894e614c98acd4fa590d0a8c9d7fd
https://europepmc.org/articles/PMC6849937/