Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Elodie Percy"'
Autor:
Elodie Percy, Alex Agrotis, Garry L. Jennings, Elizabeth A. Woodcock, Xiao-Jun Du, Xiao-Ming Gao, Anthony M. Dart, Dominic J. Autelitano
Publikováno v:
Endocrinology. 144:4097-4105
Sex differences in cardiomyopathic phenotype and the role of gonadal status were studied in mice with cardiac overexpression of beta(2)-adrenergic receptors (ARs) over 6-15 months (mo) of age. Survival to 15 mo was 96% in wild-type mice but was poore
Publikováno v:
Journal of the Neurological Sciences. 198:43-50
This study aimed to investigate the cardiac response to sympathetic stimulation and norepinephrine exposure following subarachnoid hemorrhage (SAH). Cardiac functional response was assessed 3 days following an injection of 300 microl of homologous bl
Publikováno v:
British Journal of Pharmacology. 128:774-780
We examined the existence of catecholamine metabolizing enzymes (catechol-O-methyltransferase, COMT, and monoamine oxidase, MAO) in CHO cells transfected with norepinephrine (NE) transporter (NET) cDNA. NET activity was studied by incubating cells wi
Publikováno v:
European journal of heart failure. 5(2)
Transgenic (TG) mice with cardiac specific 200-fold overexpression of beta(2)-adrenoceptors (beta(2)-AR) have a facilitated development of heart failure following thoracic aortic constriction (TAC). We have studied the alterations of intracellular Ca
Autor:
Chrishan S. Samuel, Anthony M. Dart, Elodie Percy, Rodney J. Dilley, Meryl J. Fullerton, Xiao-Jun Du, Xiao-Ming Gao
Publikováno v:
Journal of cardiovascular pharmacology. 40(4)
This paper addresses whether the enhanced left ventricular (LV) contractility and heart rate, seen in transgenic mice overexpressing beta -adrenergic receptor in the heart, might raise the incidence of LV rupture after myocardial infarct. Transgenic
Autor:
Desmond J. Sheridan, Dominic J. Autelitano, Elizabeth A. Woodcock, Elodie Percy, Xiao-Jun Du, Bing Hui Wang
Publikováno v:
Cardiovascular research. 47(1)
Objective: The α-myosin heavy chain (α-MHC) promoter is frequently used to direct cardiac specific transgene expression. We studied whether transgene expression controlled by this promoter was altered under conditions of cardiac hypertrophy and fai
Publikováno v:
Journal of the autonomic nervous system. 79(2-3)
Transgenic (TG) mice overexpressing beta(2)-adrenoceptors (AR) in the heart have enhanced beta-adrenergic activity. Since the degree of beta-adrenergic activation influences the negative chronotropic control of heart rate (HR), we studied the inhibit
Publikováno v:
Heart, Lung and Circulation. 12:A78
Publikováno v:
Journal of Molecular and Cellular Cardiology. 33:A38
Publikováno v:
Journal of Molecular and Cellular Cardiology. 33:A37