Výsledky vyhledávání - "Elodie Muzotte"

Akademický článek

Downregulation of Glutamine Synthetase, not glutaminolysis, is responsible for glutamine addiction in Notch1‐driven acute lymphoblastic leukemia

Publikováno v: Molecular Oncology, Vol 15, Iss 5, Pp 1412-1431 (2021)

The cellular receptor Notch1 is a central regulator of T‐cell development, and as a consequence, Notch1 pathway appears upregulated in > 65% of the cases of T‐cell acute lymphoblastic leukemia (T‐ALL). However, strategies targeting Notch1 signa

Externí odkaz: https://doaj.org/article/35c04b323d3d4645a1349eaea077bcd1

Zobrazit plný text záznamu

ESDR528 - Energy metabolism rewiring following acute UVB irradiation is largely dependent on nuclear DNA damage

Autor: Hamid-Reza Rezvani, Nsrein Ali, Laure Favot-Laforge, Elodie Muzotte, Lea Dousset, Walid Mahfouf, Pauline Michon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::27518db29d36c05cfc81882d6a341c50
https://doi.org/10.26226/m.62fa00a636681b001ad7e07e

Zobrazit plný text záznamu

Downregulation of Glutamine Synthetase, not glutaminolysis, is responsible for glutamine addiction in Notch1‐driven acute lymphoblastic leukemia

Publikováno v: Molecular Oncology
Molecular Oncology, Elsevier, 2021, 15 (5), pp.1412-1431. ⟨10.1002/1878-0261.12877⟩
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Molecular Oncology, Elsevier, 2021, 15, pp.1412-1431. ⟨10.1002/1878-0261.12877⟩
Digital.CSIC. Repositorio Institucional del CSIC
Molecular Oncology, Vol 15, Iss 5, Pp 1412-1431 (2021)

During glutamine sufficiency, both Notch‐positive and Notch‐negative T‐ALL cells promote glutamine catabolism, leading to mammalian target of rapamycin complex 1 (mTORC1) activation and cell growth and proliferation. However, during glutamine s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274dd93100a7d24ada66a7c0aca2aad0
https://hal-cnrs.archives-ouvertes.fr/hal-03401225

Zobrazit plný text záznamu

UVB-induced DHODH upregulation, which is driven by STAT3, is a promising target for chemoprevention and combination therapy of photocarcinogenesis

Autor: Mohsen Hosseini, Léa Dousset, Pauline Michon, Walid Mahfouf, Elodie Muzotte, Vanessa Bergeron, Doriane Bortolotto, Rodrigue Rossignol, François Moisan, Alain Taieb, Anne-Karine Bouzier-Sore, Hamid R. Rezvani

Publikováno v: Oncogenesis
Oncogenesis, Nature Publishing Group: Open Access Journals-Option C, 2019, 8 (10), ⟨10.1038/s41389-019-0161-z⟩
Oncogenesis, Vol 8, Iss 10, Pp 1-15 (2019)

The leading cause of cutaneous squamous cell carcinomas (cSCCs) is exposure to ultraviolet radiation (UV). Unlike most other cancers, the incidence rates of cSCCs are still on the rise and the treatment options currently available are limited. We hav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::452cb5191714eca3e0f2c515f93f5b29
https://hal.archives-ouvertes.fr/hal-02348219

Zobrazit plný text záznamu

Raising HDL with CETP inhibitor torcetrapib improves glucose homeostasis in dyslipidemic and insulin resistant hamsters

Autor: Clément Costard, Sylvie Sordello, Thierry Sulpice, Bénédicte Prunet-Marcassus, Quentin Thieblemont, François Briand, Elodie Muzotte

Publikováno v: Atherosclerosis. 233:359-362

We investigated whether raising HDL-cholesterol levels with cholesteryl ester transfer protein (CETP) inhibition improves glucose homeostasis in dyslipidemic and insulin resistant hamsters. Compared with vehicle, torcetrapib 30 mg/kg/day (TOR) admini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e9f30cf09200eff7f3ddf6de2bb2d1
https://doi.org/10.1016/j.atherosclerosis.2014.01.028

Zobrazit plný text záznamu

High-Fat and Fructose Intake Induces Insulin Resistance, Dyslipidemia, and Liver Steatosis and Alters In Vivo Macrophage-to-Feces Reverse Cholesterol Transport in Hamsters

Autor: Quentin Thieblemont, Thierry Sulpice, Elodie Muzotte, François Briand

Publikováno v: The Journal of Nutrition. 142:704-709

Reverse cholesterol transport (RCT) promotes the egress of cholesterol from peripheral tissues to the liver for biliary and fecal excretion. Although not demonstrated in vivo, RCT is thought to be impaired in patients with metabolic syndrome, in whic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::360f8d7c5509b11bff74d680d36e7fb6
https://doi.org/10.3945/jn.111.153197

Zobrazit plný text záznamu

Anacetrapib and dalcetrapib differentially alters HDL metabolism and macrophage-to-feces reverse cholesterol transport at similar levels of CETP inhibition in hamsters

Autor: Thierry Sulpice, Noémie Burr, Douglas G. Johns, Quentin Thieblemont, Isabelle Urbain, Elodie Muzotte, François Briand

Publikováno v: European journal of pharmacology. 740

Cholesteryl ester transfer protein (CETP) inhibitors dalcetrapib and anacetrapib differentially alter LDL- and HDL-cholesterol levels, which might be related to the potency of each drug to inhibit CETP activity. We evaluated the effects of both drugs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b341573b1c83dfec8dc4eac98cd97f2
https://pubmed.ncbi.nlm.nih.gov/25008069

Zobrazit plný text záznamu

Upregulating reverse cholesterol transport with cholesteryl ester transfer protein inhibition requires combination with the LDL-lowering drug berberine in dyslipidemic hamsters

Autor: Thierry Sulpice, François Briand, Elodie Muzotte, Quentin Thieblemont

Publikováno v: Arteriosclerosis, thrombosis, and vascular biology. 33(1)

Objective— This study aimed to investigate whether cholesteryl ester transfer protein inhibition promotes in vivo reverse cholesterol transport in dyslipidemic hamsters. Methods and Results— In vivo reverse cholesterol transport was measured afte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f2bf2de5f038a4e1d66d7938230e61d
https://pubmed.ncbi.nlm.nih.gov/23139291

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání