Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Elodie Modave"'
Autor:
Lindsay S. Cooley, Justine Rudewicz, Wilfried Souleyreau, Andrea Emanuelli, Arturo Alvarez-Arenas, Kim Clarke, Francesco Falciani, Maeva Dufies, Diether Lambrechts, Elodie Modave, Domitille Chalopin-Fillot, Raphael Pineau, Damien Ambrosetti, Jean-Christophe Bernhard, Alain Ravaud, Sylvie Négrier, Jean-Marc Ferrero, Gilles Pagès, Sebastien Benzekry, Macha Nikolski, Andreas Bikfalvi
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-21 (2021)
Abstract Background Renal Cell Carcinoma (RCC) is difficult to treat with 5-year survival rate of 10% in metastatic patients. Main reasons of therapy failure are lack of validated biomarkers and scarce knowledge of the biological processes occurring
Externí odkaz:
https://doaj.org/article/cee420b826cb4bfbb98850145497e573
Autor:
Che-Jui Lee, Elodie Modave, Bram Boeckx, Bernd Kasper, Steinar Aamdal, Michael G. Leahy, Piotr Rutkowski, Sebastian Bauer, Maria Debiec-Rychter, Raf Sciot, Diether Lambrechts, Agnieszka Wozniak, Patrick Schöffski
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5689 (2022)
Alveolar soft part sarcoma (ASPS) is a rare subtype of soft tissue sarcoma characterized by an unbalanced translocation, resulting in ASPSCR1-TFE3 fusion that transcriptionally upregulates MET expression. The European Organization for Research and Tr
Externí odkaz:
https://doaj.org/article/51327262e6074023b7fafe99638db58e
Autor:
Che-Jui Lee, Elodie Modave, Bram Boeckx, Silvia Stacchiotti, Piotr Rutkowski, Jean-Yves Blay, Maria Debiec-Rychter, Raf Sciot, Diether Lambrechts, Agnieszka Wozniak, Patrick Schöffski
Publikováno v:
Cancers, Vol 13, Iss 23, p 6057 (2021)
Clear cell sarcoma (CCSA) is characterized by a chromosomal translocation leading to EWSR1 rearrangement, resulting in aberrant transcription of multiple genes, including MET. The EORTC 90101 phase II trial evaluated the MET inhibitor crizotinib in C
Externí odkaz:
https://doaj.org/article/7426688c45f4429c86b97ba8ff8fca92
Autor:
David S. L. Ramsey, Candida Barclay, Catriona D. Campbell, Elise Dewar, Anna J. MacDonald, Elodie Modave, Sumaiya Quasim, Stephen D. Sarre
Publikováno v:
Ecology and Evolution, Vol 8, Iss 1, Pp 732-743 (2018)
Abstract The ability to detect the incursion of an invasive species or destroy the last individuals during an eradication program are some of the most difficult aspects of invasive species management. The presence of foxes in Tasmania is a contentiou
Externí odkaz:
https://doaj.org/article/e2e07cad86354d6a9d438a759a7a0002
Autor:
Agnieszka Wozniak, Diether Lambrechts, Judith V.M.G. Bovée, Raf Sciot, Maria Debiec-Rychter, Jean-Yves Blay, Hans Gelderblom, Jozef Sufliarsky, Bram Boeckx, Tom van Wezel, Elodie Modave, Patrick Schöffski, Che-Jui Lee
Significant focal CNAs detected in IMFT. Significance was determined by q value < 0.25.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fa1c5e4a974ca65f150ff4d8384dfcd
https://doi.org/10.1158/1078-0432.22483463
https://doi.org/10.1158/1078-0432.22483463
Autor:
Agnieszka Wozniak, Diether Lambrechts, Judith V.M.G. Bovée, Raf Sciot, Maria Debiec-Rychter, Jean-Yves Blay, Hans Gelderblom, Jozef Sufliarsky, Bram Boeckx, Tom van Wezel, Elodie Modave, Patrick Schöffski, Che-Jui Lee
The IMFT case with ETV6-NTRK Fusion (SeqID88), presenting characteristic morphology on H&E staining (A), with split ETV6 signal by FISH shown with arrows (B), TRK immunopositivity with pan-TRK antibody (C). On (D) a schematic presentation of the ETV6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::258bc354c39cacdb598eb25853eb044e
https://doi.org/10.1158/1078-0432.22483466.v1
https://doi.org/10.1158/1078-0432.22483466.v1
Autor:
Patrick Schöffski, Bruce A. Littlefield, Diether Lambrechts, Amy Weaver, Elodie Modave, Bram Boeckx, Agnieszka Wozniak
Example of CNA profiles obtained in LMS. Copy-number plots: x-axis represents the position on the full genome (chromosome numbers are indicated). Red dots represent normalized read count for bins of 50Kb (log R value). Y-values around 0 represent cop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b898f8f66da61f4d38b033139c02234
https://doi.org/10.1158/1078-0432.22478406
https://doi.org/10.1158/1078-0432.22478406
Autor:
Patrick Schöffski, Bruce A. Littlefield, Diether Lambrechts, Amy Weaver, Elodie Modave, Bram Boeckx, Agnieszka Wozniak
Significant focal events detected in leiomyosarcoma from EISAI 309 trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a9b1a7f0e20c26a362795cceafb33f
https://doi.org/10.1158/1078-0432.22478403.v1
https://doi.org/10.1158/1078-0432.22478403.v1
Autor:
Annette T. Byrne, Jochen H.M. Prehn, Livio Trusolino, Claudio Isella, Andrea Bertotti, Diether Lambrechts, Enzo Medico, Rodrigo Dienstmann, Josep Tabernero, Guillem Argilés, Patrick Dicker, Matthias P.A. Ebert, Johannes Betge, Luise Halang, Bram Boeckx, Elodie Modave, Evy Vanderheyden, Manuela Salvucci, Eugenia R. Zanella, Francesco Sassi, Andreas U. Lindner, Niraj Khemka, Giorgia Migliardi, Alice C. O'Farrell, Adam Lafferty
Purpose:Regorafenib (REG) is approved for the treatment of metastatic colorectal cancer, but has modest survival benefit and associated toxicities. Robust predictive/early response biomarkers to aid patient stratification are outstanding. We have exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b03cb7f23937564cd04f0a66b41f08cc
https://doi.org/10.1158/1078-0432.c.6530519
https://doi.org/10.1158/1078-0432.c.6530519
Autor:
Agnieszka Wozniak, Diether Lambrechts, Judith V.M.G. Bovée, Raf Sciot, Maria Debiec-Rychter, Jean-Yves Blay, Hans Gelderblom, Jozef Sufliarsky, Bram Boeckx, Tom van Wezel, Elodie Modave, Patrick Schöffski, Che-Jui Lee
Purpose:The European Organization for Research and Treatment of Cancer (EORTC) clinical phase II trial 90101 “CREATE” showed high antitumor activity of crizotinib, an inhibitor of anaplastic lymphoma kinase (ALK)/ROS1, in patients with advanced i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890b60e6a3b9e4683c0f4c6f039dfe0c
https://doi.org/10.1158/1078-0432.c.6531155
https://doi.org/10.1158/1078-0432.c.6531155