A Genetic Toolbox for the New Model Cyanobacterium Cyanothece PCC 7425: A Case Study for the Photosynthetic Production of Limonene

Autor: Célia Chenebault, Encarnación Diaz-Santos, Xavier Kammerscheit, Sigrid Görgen, Cristian Ilioaia, Simona Streckaite, Andrew Gall, Bruno Robert, Elodie Marcon, David-Alexandre Buisson, Karim Benzerara, Jean-François Sassi, Corinne Cassier-Chauvat, Franck Chauvat

Publikováno v: Frontiers in Microbiology, Vol 11 (2020)

Cyanobacteria, the largest phylum of prokaryotes, perform oxygenic photosynthesis and are regarded as the ancestors of the plant chloroplast and the purveyors of the oxygen and biomass that shaped the biosphere. Nowadays, cyanobacteria are attracting

Externí odkaz: https://doaj.org/article/34a2aaea21d846f9922813b84e831a91

High Therapeutic Efficacy of a New Survivin LSP-Cancer Vaccine Containing CD4+ and CD8+ T-Cell Epitopes

Autor: Fanny Onodi, Chahrazed Maherzi-Mechalikh, Alice Mougel, Nadine Ben Hamouda, Charlotte Taboas, Fabien Gueugnon, Thi Tran, Herve Nozach, Elodie Marcon, Alain Gey, Magali Terme, Ahmed Bouzidi, Bernard Maillere, Jérôme Kerzerho, Eric Tartour, Corinne Tanchot

Publikováno v: Frontiers in Oncology, Vol 8 (2018)

The efficacy of an antitumoral vaccine relies both on the choice of the antigen targeted and on its design. The tumor antigen survivin is an attractive target to develop therapeutic cancer vaccines because of its restricted over-expression and vital

Externí odkaz: https://doaj.org/article/43e160a05d214c13a00c49f6818b6840

Engineering of three-finger fold toxins creates ligands with original pharmacological profiles for muscarinic and adrenergic receptors.

Autor: Carole Fruchart-Gaillard, Gilles Mourier, Guillaume Blanchet, Laura Vera, Nicolas Gilles, Renée Ménez, Elodie Marcon, Enrico A Stura, Denis Servent

Publikováno v: PLoS ONE, Vol 7, Iss 6, p e39166 (2012)

Protein engineering approaches are often a combination of rational design and directed evolution using display technologies. Here, we test "loop grafting," a rational design method, on three-finger fold proteins. These small reticulated proteins have

Externí odkaz: https://doaj.org/article/9adc81d3dd3f489380a647abc957dc11

Dynamics of the localization of the plastid terminal oxidase PTOX inside the chloroplast

Autor: Elodie Marcon, Lucas Moyet, Susanne Bolte, Anja Krieger-Liszkay, Mélanie Jaunario, Marie-Thérèse Paternostre, Marcel Kuntz

Publikováno v: Journal of Experimental Botany
Journal of Experimental Botany, Oxford University Press (OUP), 2020, 71 (9), pp.2661-2669. ⟨10.1093/jxb/eraa074⟩
Journal of Experimental Botany, 2020, 71 (9), pp.2661-2669. ⟨10.1093/jxb/eraa074⟩

The plastid terminal oxidase (PTOX) is a plastohydroquinone:oxygen oxidoreductase that shares structural similarities with alternative oxidases (AOXs). Multiple roles have been attributed to PTOX, such as involvement in carotene desaturation, a safet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::365cfd2f897e59bea6ee35d410817f0e
https://hal.archives-ouvertes.fr/hal-02495692/document

Efficient Access to Deuterated and Tritiated Nucleobase Pharmaceuticals and Oligonucleotides using Hydrogen-Isotope Exchange

Autor: Alberto Palazzolo, Sophie Feuillastre, Viktor Pfeifer, Sébastien Garcia‐Argote, Donia Bouzouita, Simon Tricard, Céline Chollet, Elodie Marcon, David‐Alexandre Buisson, Sophie Cholet, François Fenaille, Guy Lippens, Bruno Chaudret, Grégory Pieters

Publikováno v: Angewandte Chemie International Edition
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2019, ⟨10.1002/anie.201813946⟩
Angewandte Chemie International Edition, 2019, 58 (15), pp.4891-4895. ⟨10.1002/anie.201813946⟩
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2019, 58 (15), pp.4891-4895. ⟨10.1002/anie.201813946⟩
Angewandte Chemie (International Edition) 15 (58), 4891-4895. (2019)
Angewandte Chemie (International Ed. in English)

International audience; A general approach for the efficient hydrogen-isotope exchange of nucleobase derivatives is described. Catalyzed by ruthenium nanoparticles, using mild reaction conditions, and involving either D2 or T2 as isotopic sources, th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e0f0a62f2cf46b56857c6f65baa08a
https://hal-cea.archives-ouvertes.fr/cea-02075752/document