Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Elodie Lafont"'
Publikováno v:
Cell Death and Disease, Vol 13, Iss 3, Pp 1-32 (2022)
Abstract Cell death plays a pivotal role in the maintenance of tissue homeostasis. Key players in the controlled induction of cell death are the Death Receptors (DR). CD95 is a prototypic DR activated by its cognate ligand CD95L triggering programmed
Externí odkaz:
https://doaj.org/article/a71a0b6b44c74e21befc821eb4e9df7f
Autor:
Peter Draber, Sebastian Kupka, Matthias Reichert, Helena Draberova, Elodie Lafont, Diego de Miguel, Lisanne Spilgies, Silvia Surinova, Lucia Taraborrelli, Torsten Hartwig, Eva Rieser, Luigi Martino, Katrin Rittinger, Henning Walczak
Publikováno v:
Cell Reports, Vol 13, Iss 10, Pp 2258-2272 (2015)
Ubiquitination and deubiquitination are crucial for assembly and disassembly of signaling complexes. LUBAC-generated linear (M1) ubiquitin is important for signaling via various immune receptors. We show here that the deubiquitinases CYLD and A20, bu
Externí odkaz:
https://doaj.org/article/6c17437bc05345f6a259e00153b83b21
Autor:
Elodie Lafont
Publikováno v:
Cancers, Vol 12, Iss 5, p 1113 (2020)
Throughout tumour progression, tumour cells are exposed to various intense cellular stress conditions owing to intrinsic and extrinsic cues, to which some cells are remarkably able to adapt. Death Receptor (DR) signalling and the Unfolded Protein Res
Externí odkaz:
https://doaj.org/article/09979fc4dd5f4702b6a204ee52cdb640
Autor:
Guillaume Poiroux, Marguerite Pitié, Raphaël Culerrier, Elodie Lafont, Bruno Ségui, Els J M Van Damme, Willy J Peumans, Jean Bernadou, Thierry Levade, Pierre Rougé, Annick Barre, Hervé Benoist
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23315 (2011)
Photochemotherapy is used both for solid tumors and in extracorporeal treatment of various hematologic disorders. Nevertheless, its development in oncology remains limited, because of the low selectivity of photosensitizers (PS) towards human tumor c
Externí odkaz:
https://doaj.org/article/a8620ab1c7fd4b5fb175c50679e15cb8
Autor:
Elodie Lafont, Delphine Milhas, Justin Teissié, Nicole Therville, Nathalie Andrieu-Abadie, Thierry Levade, Hervé Benoist, Bruno Ségui
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13638 (2010)
BACKGROUND: Upon CD95/Fas ligation, the initiator caspase-8 is known to activate effector caspases leading to apoptosis. In the presence of zVAD-fmk, a broad-spectrum caspase inhibitor, Fas engagement can also trigger an alternative, non-apoptotic ca
Externí odkaz:
https://doaj.org/article/ea9c17dbfb6f4e78befe4634b7dda3bf
Autor:
Elodie Lafont, Tony Avril
Publikováno v:
FEBS Journal
FEBS Journal, 2023, ⟨10.1111/febs.16774⟩
FEBS Journal, 2023, ⟨10.1111/febs.16774⟩
International audience; The endoplasmic reticulum (ER) is the organelle where the production and shaping of most secreted and transmembrane proteins happens. ER function is finely regulated to prevent accumulation of misfolded proteins generating ER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fa2c2948acc53d11e71fed6b294cc02
https://hal.science/hal-04062149
https://hal.science/hal-04062149
Autor:
Diana Pelizzari-Raymundo, Raphael Pineau, Alexandra Papaioannou, Xingchen Zhou, Sophie Martin, Tony Avril, Matthieu Le Gallo, Eric Chevet, Elodie Lafont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0eb6de596e5724ef57ae8b060893217a
https://doi.org/10.15252/rc.2023949760
https://doi.org/10.15252/rc.2023949760
Publikováno v:
Biochimica et Biophysica Acta-Molecular Cell Research
Biochimica et Biophysica Acta-Molecular Cell Research, 2021, 1868 (6), pp.119001. ⟨10.1016/j.bbamcr.2021.119001⟩
Biochimica et Biophysica Acta-Molecular Cell Research, Elsevier, 2021, 1868 (6), pp.119001. ⟨10.1016/j.bbamcr.2021.119001⟩
Biochimica et Biophysica Acta-Molecular Cell Research, 2021, 1868 (6), pp.119001. ⟨10.1016/j.bbamcr.2021.119001⟩
Biochimica et Biophysica Acta-Molecular Cell Research, Elsevier, 2021, 1868 (6), pp.119001. ⟨10.1016/j.bbamcr.2021.119001⟩
International audience; Endoplasmic Reticulum (ER) stress signaling is an adaptive mechanism triggered when protein folding demand overcomes the folding capacity of this compartment, thereby leading to the accumulation of improperly folded proteins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c686ff856b15ccf0d8d573cd2969990
https://hal.science/hal-03194479
https://hal.science/hal-03194479
Autor:
Andreas Linkermann, Stephen Henderson, Helena Draberova, Katarzyna Wojdyla, Diego de Miguel, Avigayil Chalk, Elodie Lafont, Anne von Mässenhausen, Sebastian Kupka, Eva Rieser, Amandeep Bhamra, Matthias Reichert, Henning Walczak, Silvia Surinova, Peter Draber
Publikováno v:
Nature cell biology
The linear-ubiquitin chain assembly complex (LUBAC) modulates signalling via various immune receptors. In tumour necrosis factor (TNF) signalling, linear (also known as M1) ubiquitin enables full gene activation and prevents cell death. However, the