Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Elodie Labit"'
Autor:
Matthieu Drouyer, Tak-Ho Chu, Elodie Labit, Florencia Haase, Renina Gale Navarro, Deborah Nazareth, Nicole Rosin, Jessica Merjane, Suzanne Scott, Marti Cabanes-Creus, Adrian Westhaus, Erhua Zhu, Rajiv Midha, Ian E. Alexander, Jeff Biernaskie, Samantha L. Ginn, Leszek Lisowski
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101234- (2024)
Gene therapies and associated technologies are transforming biomedical research and enabling novel therapeutic options for patients living with debilitating and incurable genetic disorders. The vector system based on recombinant adeno-associated vira
Externí odkaz:
https://doaj.org/article/25d01544733d4f349e805a8d768d1b0c
Autor:
Suchit Ahuja, Cynthia Adjekukor, Qing Li, Katrinka M Kocha, Nicole Rosin, Elodie Labit, Sarthak Sinha, Ankita Narang, Quan Long, Jeff Biernaskie, Peng Huang, Sarah J Childs
Publikováno v:
PLoS Biology, Vol 22, Iss 4, p e3002590 (2024)
Brain pericytes are one of the critical cell types that regulate endothelial barrier function and activity, thus ensuring adequate blood flow to the brain. The genetic pathways guiding undifferentiated cells into mature pericytes are not well underst
Externí odkaz:
https://doaj.org/article/f95a0821ffab4be49de28da144fa1730
Autor:
Ana Nikolic, Francesca Maule, Anna Bobyn, Katrina Ellestad, Seungil Paik, Sajid A. Marhon, Parinaz Mehdipour, Xueqing Lun, Huey-Miin Chen, Claire Mallard, Alexander J. Hay, Michael J. Johnston, Christopher J. Gafuik, Franz J. Zemp, Yaoqing Shen, Nicoletta Ninkovic, Katalin Osz, Elodie Labit, N. Daniel Berger, Duncan K. Brownsey, John J. Kelly, Jeff Biernaskie, Peter B. Dirks, Darren J. Derksen, Steven J. M. Jones, Donna L. Senger, Jennifer A. Chan, Douglas J. Mahoney, Daniel D. De Carvalho, Marco Gallo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Self-renewal is a crucial property of glioblastoma cells that is enabled by the choreographed functions of chromatin regulators and transcription factors. Identifying targetable epigenetic mechanisms of self-renewal could therefore represent
Externí odkaz:
https://doaj.org/article/028fa80da48448499589471060a20e19
Autor:
Roman J. Krawetz, Saleem Abubacker, Catherine Leonard, Anand O. Masson, Sophia Shah, Nadia Narendran, Pankaj Tailor, Suresh C. Regmi, Elodie Labit, Nicoletta Ninkovic, Jessica May Corpuz, Kenichi Ito, T. Michael Underhill, Paul T. Salo, Tannin A. Schmidt, Jeff A. Biernaskie
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-18 (2022)
Abstract The wound healing response is one of most primitive and conserved physiological responses in the animal kingdom, as restoring tissue integrity/homeostasis can be the difference between life and death. Wound healing in mammals is mediated by
Externí odkaz:
https://doaj.org/article/6cfd5dea43f0478bbcc1d17da0a3891f
Autor:
Lise Rabiller, Elodie Labit, Christophe Guissard, Silveric Gilardi, Bruno P. Guiard, Lionel Moulédous, Marine Silva, Gilles Mithieux, Luc Pénicaud, Anne Lorsignol, Louis Casteilla, Cécile Dromard
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-9 (2021)
Abstract Tissue repair after injury in adult mammals, usually results in scarring and loss of function in contrast to lower vertebrates such as the newt and zebrafish that regenerate. Understanding the regulatory processes that guide the outcome of t
Externí odkaz:
https://doaj.org/article/8033854e31854982939604c70d5220b7
Autor:
Lise Rabiller, Virginie Robert, Adèle Arlat, Elodie Labit, Marielle Ousset, Marie Salon, Agnès Coste, Léa Da Costa-Fernandes, Paul Monsarrat, Bruno Ségui, Mireille André, Christophe Guissard, Marie-Laure Renoud, Marine Silva, Gilles Mithieux, Isabelle Raymond-Letron, Luc Pénicaud, Anne Lorsignol, Louis Casteilla, Cécile Dromard Berthézène, Béatrice Cousin
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-12 (2021)
Abstract Tissue repair after lesion usually leads to scar healing and thus loss of function in adult mammals. In contrast, other adult vertebrates such as amphibians have the ability to regenerate and restore tissue homeostasis after lesion. Understa
Externí odkaz:
https://doaj.org/article/7ce0827820f24724903bce91e7add729
Autor:
Andrew Hagner, Wisoo Shin, Sarthak Sinha, Whitney Alpaugh, Matthew Workentine, Sepideh Abbasi, Waleed Rahmani, Natacha Agabalyan, Nilesh Sharma, Holly Sparks, Jessica Yoon, Elodie Labit, John Cobb, Ina Dobrinski, Jeff Biernaskie
Publikováno v:
iScience, Vol 23, Iss 4, Pp - (2020)
Summary: The adult hair follicle (HF) undergoes successive regeneration driven by resident epithelial stem cells and neighboring mesenchyme. Recent work described the existence of HF dermal stem cells (hfDSCs), but the genetic regulation of hfDSCs an
Externí odkaz:
https://doaj.org/article/ec45bef5dc8949899815688f09c6d64d
Autor:
Elodie Luche, Virginie Robert, Vincent Cuminetti, Celine Pomié, Quentin Sastourné-Arrey, Aurélie Waget, Emmanuelle Arnaud, Audrey Varin, Elodie Labit, Patrick Laharrague, Remy Burcelin, Louis Casteilla, Beatrice Cousin
Publikováno v:
eLife, Vol 6 (2017)
Activation and increased numbers of inflammatory macrophages, in adipose tissue (AT) are deleterious in metabolic diseases. Up to now, AT macrophages (ATM) accumulation was considered to be due to blood infiltration or local proliferation, although t
Externí odkaz:
https://doaj.org/article/a36efdf50ddf4a528c94d1e075a61494
Autor:
Rachel M. Kratofil, Hanjoo B. Shim, Raymond Shim, Woo Yong Lee, Elodie Labit, Sarthak Sinha, Catherine M. Keenan, Bas G. J. Surewaard, Ji Yeon Noh, Yuxiang Sun, Keith A. Sharkey, Matthias Mack, Jeff Biernaskie, Justin F. Deniset, Paul Kubes
Publikováno v:
Nature. 609:166-173
Autor:
Antoine Dufour, Raquel Farias, Leslie Cao, Mark R. Gillrie, Braedon McDonald, Bryan G. Yipp, Nicole L. Rosin, Angela P. Nguyen, Arzina Jaffer, Elodie Labit, Sarthak Sinha, Amy Bromley, Luiz Gustavo de Almeida, Jeff Biernaskie, Marvin J. Fritzler, Rohit Arora
Publikováno v:
Nature Reviews. Immunology
Nature Medicine
Nature Medicine
Although critical for host defense, innate immune cells are also pathologic drivers of acute respiratory distress syndrome (ARDS). Innate immune dynamics during Coronavirus Disease 2019 (COVID-19) ARDS, compared to ARDS from other respiratory pathoge