Výsledky vyhledávání - "Elodie Henriet"

Akademický článek

Targeting TGF-β1/miR-21 Pathway in Keratinocytes Reveals Protective Effects of Silymarin on Imiquimod-Induced Psoriasis Mouse Model

Autor: Elodie Henriet, Florence Abdallah, Yoan Laurent, Cyril Guimpied, Emily Clement, Michel Simon, Chantal Pichon, Patrick Baril

Publikováno v: JID Innovations, Vol 3, Iss 3, Pp 100175- (2023)

Epidermal cells integrate multiple signals that activate the signaling pathways involved in skin homeostasis. TGF-β1 signaling pathway upregulates microRNA (miR)-21-5p in keratinocytes and is often deregulated in skin diseases. To identify the bioac

Externí odkaz: https://doaj.org/article/48f78fe2b7774cda97eb689eea411ea4

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Akademický článek

Morphology-guided transcriptomic analysis of human pancreatic cancer organoids reveals microenvironmental signals that enhance invasion

Publikováno v: The Journal of Clinical Investigation, Vol 133, Iss 8 (2023)

Pancreatic ductal adenocarcinoma (PDAC) frequently presents with metastasis, but the molecular programs in human PDAC cells that drive invasion are not well understood. Using an experimental pipeline enabling PDAC organoid isolation and collection ba

Externí odkaz: https://doaj.org/article/877a49b959a144a8a641ca1dc42fec86

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Akademický článek

Purine Biosynthesis Pathways Are Required for Myogenesis in Xenopus laevis

Autor: Maëlle Duperray, Fanny Hardet, Elodie Henriet, Christelle Saint-Marc, Eric Boué-Grabot, Bertrand Daignan-Fornier, Karine Massé, Benoît Pinson

Publikováno v: Cells, Vol 12, Iss 19, p 2379 (2023)

Purines are required for fundamental biological processes and alterations in their metabolism lead to severe genetic diseases associated with developmental defects whose etiology remains unclear. Here, we studied the developmental requirements for pu

Externí odkaz: https://doaj.org/article/f76fcca561704dcd84739d4684061716

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Akademický článek

Combining laser capture microdissection and proteomics reveals an active translation machinery controlling invadosome formation

Autor: Zakaria Ezzoukhry, Elodie Henriet, Fabrice P. Cordelières, Jean-William Dupuy, Marlène Maître, Nathan Gay, Sylvaine Di-Tommaso, Luc Mercier, Jacky G. Goetz, Marion Peter, Frédéric Bard, Violaine Moreau, Anne-Aurélie Raymond, Frédéric Saltel

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)

Invadosomes degrade extracellular matrix and facilitate cell invasion but their molecular composition is not fully understood. Here, the authors combine laser capture and mass spectrometry to map the proteome of invadosomes, showing that they rely on

Externí odkaz: https://doaj.org/article/2c995818d6d044ceb85f3e411b0ea6e8

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Akademický článek

miR-21-3p/IL-22 Axes Are Major Drivers of Psoriasis Pathogenesis by Modulating Keratinocytes Proliferation-Survival Balance and Inflammatory Response

Autor: Florence Abdallah, Elodie Henriet, Amandine Suet, Ali Arar, Rudy Clemençon, Jean-Marc Malinge, Gaël Lecellier, Patrick Baril, Chantal Pichon

Publikováno v: Cells, Vol 10, Iss 10, p 2547 (2021)

Psoriasis is a chronic inflammatory skin disease that is mediated by complex crosstalk between immune cells and keratinocytes (KCs). Emerging studies have showed a specific psoriatic microRNAs signature, in which miR-21 is one of the most upregulated

Externí odkaz: https://doaj.org/article/31402c5e25124348af629a1fc76c61d3

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Supplementary Data from Tumor-Resident Stromal Cells Promote Breast Cancer Invasion through Regulation of the Basal Phenotype

Autor: Andrew J. Ewald, Gareth J. Thomas, Orit Katarina Sirka, Elodie Henriet, Christopher J. Hanley

Supplementary Materials and Methods. Figure S1. Weighted gene correlation network analysis of RNA-Sequencing from human invasive ductal breast cancer primary tumor samples.Figure S2: Physical interaction between stromal cells and invasive organoids.F

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0319f79db58113c12ed2728f890bb6
https://doi.org/10.1158/1541-7786.22525823

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Data from Tumor-Resident Stromal Cells Promote Breast Cancer Invasion through Regulation of the Basal Phenotype

Autor: Andrew J. Ewald, Gareth J. Thomas, Orit Katarina Sirka, Elodie Henriet, Christopher J. Hanley

Collective invasion can be led by breast cancer cells expressing basal epithelial markers, typified by keratin-14 (KRT14). We analyzed gene expression data from The Cancer Genome Atlas and demonstrated a significant correlation between a KRT14+ invas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30d7f15cdf23b158c4bb7224a9382bb2
https://doi.org/10.1158/1541-7786.c.6544919

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