Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Elodie Bouaziz"'
Autor:
Karl Götze, Agathe Vrillon, Julien Dumurgier, Sandrine Indart, Marta Sanchez-Ortiz, Hela Slimi, Agathe Raynaud-Simon, Emmanuel Cognat, Matthieu Martinet, Henrik Zetterberg, Kaj Blennow, Claire Hourrègue, Elodie Bouaziz-Amar, Claire Paquet, Matthieu Lilamand
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract Background Analysis of selected research cohorts has highlighted an association between plasma neurofilament light (NfL) protein and cross-sectional cognitive impairment as well as longitudinal cognitive decline. However, the findings have y
Externí odkaz:
https://doaj.org/article/72b22a4a79ff4ee783c0c7dbfa0db7ee
Autor:
Louise Sindzingre, Elodie Bouaziz-Amar, François Mouton-Liger, Emmanuel Cognat, Julien Dumurgier, Agathe Vrillon, Claire Paquet, Matthieu Lilamand
Publikováno v:
The Journal of Nutrition, Health and Aging, Vol 28, Iss 3, Pp 100166- (2024)
Adiponectin is an adipokine playing a central role in the regulation of energy homeostasis, carbohydrate and lipid metabolism, as well as immunomodulation. The relationship between Alzheimer’s disease (AD) and body composition has highlighted the b
Externí odkaz:
https://doaj.org/article/283fc908e50745bc80613a95ba9c8b60
Autor:
Holger Hummerich, Helen Speedy, Tracy Campbell, Lee Darwent, Elizabeth Hill, Steven Collins, Christiane Stehmann, Gabor G Kovacs, Michael D Geschwind, Karl Frontzek, Herbert Budka, Ellen Gelpi, Adriano Aguzzi, Sven J van der Lee, Cornelia M van Duijn, Pawel P Liberski, Miguel Calero, Pascual Sanchez-Juan, Elodie Bouaziz-Amar, Jean-Louis Laplanche, Stéphane Haïk, Jean-Phillipe Brandel, Angela Mammana, Sabina Capellari, Anna Poleggi, Anna Ladogana, Maurizio Pocchiari, Saima Zafar, Stephanie Booth, Gerard H Jansen, Aušrinė Areškevičiūtė, Eva Løbner Lund, Katie Glisic, Piero Parchi, Peter Hermann, Inga Zerr, Brian S Appleby, Jiri Safar, Pierluigi Gambetti, John Collinge, Simon Mead
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0304528 (2024)
Human prion diseases are rare, transmissible and often rapidly progressive dementias. The most common type, sporadic Creutzfeldt-Jakob disease (sCJD), is highly variable in clinical duration and age at onset. Genetic determinants of late onset or slo
Externí odkaz:
https://doaj.org/article/a8105e366d44473aa02be9676f81d759
Autor:
Mélina Régy, Aline Dugravot, Séverine Sabia, Elodie Bouaziz-Amar, Claire Paquet, Bernard Hanseeuw, Archana Singh-Manoux, Julien Dumurgier
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract Background Alzheimer’s disease (AD) is the 5th leading cause of death in people 65 years and older. The ATN classification reflects a biological definition of AD pathology with markers of Aβ deposition (A), pathologic tau (T), and neurode
Externí odkaz:
https://doaj.org/article/7aa860f4a1e64498a732358a004133dc
Autor:
Agathe Vrillon, François Mouton-Liger, Matthieu Martinet, Emmanuel Cognat, Claire Hourregue, Julien Dumurgier, Elodie Bouaziz-Amar, Ann Brinkmalm, Kaj Blennow, Henrik Zetterberg, Jacques Hugon, Claire Paquet
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-11 (2022)
Abstract Background Synaptic dysfunction is an early core feature of Alzheimer’s disease (AD), closely associated with cognitive symptoms. Neuregulin 1 (NRG1) is a growth and differentiation factor with a key role in the development and maintenance
Externí odkaz:
https://doaj.org/article/041e8a55706645c0bccada9c89ee30db
Autor:
Karl Götze, Agathe Vrillon, Elodie Bouaziz-Amar, François Mouton-Liger, Jacques Hugon, Matthieu Martinet, Julien Dumurgier, Emmanuel Cognat, Henrik Zetterberg, Kaj Blennow, Claire Hourrègue, Claire Paquet, Matthieu Lilamand
Publikováno v:
Neurobiology of Disease, Vol 176, Iss , Pp 105937- (2023)
Objective: To explore the accuracy of plasma neurofilament light chain (NfL) as a biomarker for diagnosis and staging of cognitive impairment, in a large cohort with of previously diagnosed patients in clinical practice. Methods: Retrospective, cross
Externí odkaz:
https://doaj.org/article/9cd361e53791475ba1a459004f177c11
Autor:
Annika Öhrfelt, Julien Dumurgier, Henrik Zetterberg, Agathe Vrillon, Nicholas J. Ashton, Hlin Kvartsberg, Elodie Bouaziz-Amar, Jacques Hugon, Claire Paquet, Kaj Blennow
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2020)
Abstract Background Neurogranin (Ng) is a neuron-specific and postsynaptic protein that is abundantly expressed in the brain, particularly in the dendritic spine of the hippocampus and cerebral cortex. The enzymatic cleavage of Ng produces fragments
Externí odkaz:
https://doaj.org/article/2e267cb39ee344b68223549681635402
Autor:
Sylvain Lehmann, Julien Dumurgier, Xavier Ayrignac, Cecilia Marelli, Daniel Alcolea, Juan Fortea Ormaechea, Eric Thouvenot, Constance Delaby, Christophe Hirtz, Jérôme Vialaret, Nelly Ginestet, Elodie Bouaziz-Amar, Jean-Louis Laplanche, Pierre Labauge, Claire Paquet, Alberto Lleo, Audrey Gabelle, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-12 (2020)
Abstract Background Amyloid pathology, which is one of the characteristics of Alzheimer’s disease (AD), results from altered metabolism of the beta-amyloid (Aβ) peptide in terms of synthesis, clearance, or aggregation. A decrease in cerebrospinal
Externí odkaz:
https://doaj.org/article/aca109942c8141949ef7cdc389b65448
Autor:
François Mouton-Liger, Julien Dumurgier, Emmanuel Cognat, Claire Hourregue, Henrik Zetterberg, Hugo Vanderstichele, Eugeen Vanmechelen, Elodie Bouaziz-Amar, Kaj Blennow, Jacques Hugon, Claire Paquet
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-10 (2020)
Abstract Background The presynaptic protein neuregulin1 (NRG1) is cleaved by beta-site APP cleaving enzyme 1 (BACE1) in a similar way as amyloid precursor protein (APP) NRG1 can activate post-synaptic receptor tyrosine-protein kinase erbB4 (ErbB4) an
Externí odkaz:
https://doaj.org/article/8684adc4a477497daf12a79dafe645b7
Autor:
Hélène Pouclet‐Courtemanche, Tri‐Bao Nguyen, Emilie Skrobala, Claire Boutoleau‐Bretonnière, Florence Pasquier, Elodie Bouaziz‐Amar, Edith Bigot‐Corbel, Susanna Schraen, Julien Dumurgier, Claire Paquet, Thibaud Lebouvier
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 161-169 (2019)
Abstract Introduction Patients with positive tauopathy but negative Aβ42 (A−T+) in the cerebrospinal fluid (CSF) represent a diagnostic challenge. The Aβ42/40 ratio supersedes Aβ42 and reintegrates “false” A−T+ patients into the Alzheimer'
Externí odkaz:
https://doaj.org/article/b451a21342644f32b03913fd70713b37